CBP-IN-1

Product Name: CBP-IN-1
CAS No.: 2222941-37-7
Chemical Name: CBP-IN-1
Synonyms: CCS-1477;CCS147;CCS1477;CBP-IN-1;Inobrodib;CBP inhibitor 1;CBP-IN-1 (CCS1477);CCS-1477(CBP-IN-1);CCS-1477 (CCS1477);Inobrodib (CCS1477)
CBNumber: CB85419700
Molecular Formula: C30H32F2N4O3
Formula Weight: 534.6
MOL File: 2222941-37-7.mol

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CBP-IN-1 Property

Boiling point:: 761.0±60.0 °C(Predicted)
Density: 1.37±0.1 g/cm3(Predicted)
storage temp.: Store at -20°C
solubility: Ethanol:100.0(Max Conc. mg/mL);187.06(Max Conc. mM)
form: A solid
pka: 4.40±0.10(Predicted)
color: White to off-white
InChIKey: SKDNDJWEBPQKCS-CLHVYKLBSA-N
SMILES: N1(C2=CC=C(F)C(F)=C2)[C@H](C2N([C@@H]3CC[C@@H](OC)CC3)C3=CC=C(C4=C(C)ON=C4C)C=C3N=2)CCCC1=O

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P312Call a POISON CENTER or doctor/physician if you feel unwell.

P362Take off contaminated clothing and wash before reuse.

P403+P233Store in a well-ventilated place. Keep container tightly closed.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

ChemScene

Product number: CS-0091862
Product name: CBP/p300-IN-4
Purity: 99.83%
Packaging: 5mg
Price: $230
Updated: 2021/12/16

ChemScene

Product number: CS-0091862
Product name: CBP/p300-IN-4
Purity: 99.83%
Packaging: 50mg
Price: $1200
Updated: 2021/12/16

DC Chemicals

Product number: DC31451
Product name: CCS-1477
Packaging: 100mg
Price: $700
Updated: 2021/12/16

DC Chemicals

Product number: DC31451
Product name: CCS-1477
Packaging: 250mg
Price: $1300
Updated: 2021/12/16

DC Chemicals

Product number: DC31451
Product name: CCS-1477
Packaging: 1g
Price: $2600
Updated: 2021/12/16

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CBP-IN-1 Chemical Properties,Usage,Production

Uses

(6S)-1-(3,4-Difluorophenyl)-6-[5-(3,5-dimethyl-4-isoxazolyl)-1-(trans-4-methoxycyclohexyl)-1H-benzimidazol-2-yl]-2-piperidinone is used for the treatment of genetic disease related to the expression of c9orf72 (brain expressed, associated with NEDD4)

in vivo

Inobrodib (10-30 mg/kg; oral gavage; 10 or 20 mg/kg daily (QD) or 30 mg/kg every other day (QOD) for 28 days) suppresses growth of a 22Rv1 mouse xenograft model with associated reduction in AR signaling^[1].
? Inobrodib (20 mg/kg; oral gavage; daily for 8 days) decreases AR and AR-V7 signaling and inhibits growth in a patient- derived model of lethal prostate cancer (NOD/SCID gamma (NSG) male castrated mice)^[1].

Animal Model:	Noncastrated male athymic nude mice^[1]
Dosage:	10-30 mg/kg
Administration:	Oral gavage; at 10 or 20 mg/kg daily (QD) or at 30 mg/kg every other day (QOD) for 28 days
Result:	Affected tumor growth at 10 mg/kg daily, 20 mg/kg daily, and 30 mg/kg every other day.

CBP-IN-1 Preparation Products And Raw materials

Raw materials

Preparation Products

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CBP-IN-1 Suppliers

China 63 United States 7 Global 70

Nantong Hi-Future Biotechnology Co., Ltd

Tel: 18051384581
Email: sales@chemhifuture.com
Country: China
ProdList: 2998
Advantage: 58

Nanjing Chemlin Chemical Co., Ltd

Tel: 025-83697070
Fax: +86-25-83453306
Email: info@chemlin.com.cn
Country: China
ProdList: 16077
Advantage: 64

Sichuan Wei Keqi Biological Technology Co., Ltd.

Tel: 028-81700200 18116577057
Fax: 028-81705658
Email: 3003855609@qq.com
Country: China
ProdList: 7778
Advantage: 56

Shanghai XingMo Biotechnology Co., Ltd.

Tel: +86 13524779951; 13524779951
Fax: QQ: 2075692521
Email: 2075692521@qq.com
Country: China
ProdList: 301
Advantage: 55

Shanghai Lollane Biological Technology Co.,Ltd.

Tel: 021-52996696，15000506266 15000506266
Fax: +86-21-52996696
Country: China
ProdList: 4768
Advantage: 55

Shanghai EFE Biological Technology Co., Ltd.

Tel: 021-65675885 18964387627
Fax: 021-65675885
Email: info@efebio.com
Country: China
ProdList: 9803
Advantage: 58

Shanghai YuanYe Biotechnology Co., Ltd.

Tel: 021-61312847; 18021002903
Fax: QQ:3008007432
Email: 3008007409@qq.com
Country: China
ProdList: 71826
Advantage: 60

ShangHai Biochempartner Co.,Ltd

Tel: 177-54423994 17754423994
Fax: QQ:2853530913
Email: 2853530910@QQ.com
Country: China
ProdList: 8000
Advantage: 62

Amadis Chemical Company Limited

Tel: 571-89925085
Fax: 0086-571-89925065
Email: sales@amadischem.com
Country: China
ProdList: 131957
Advantage: 58

Chuzhou KeMail Chemical Technology Co., Ltd

Tel: 0550-5196001 15000891977
Fax: 0550-5196001
Email: wj520wjxby@126.com
Country: China
ProdList: 1944
Advantage: 55

2222941-37-7, CBP-IN-1Related Search:

CBP-IN-1

CCS1477

CCS-1477

CBP inhibitor 1

2-Piperidinone, 1-(3,4-difluorophenyl)-6-[5-(3,5-dimethyl-4-isoxazolyl)-1-(trans-4-methoxycyclohexyl)-1H-benzimidazol-2-yl]-, (6S)-

CCS-1477(CBP-IN-1)

CCS147

CBP-IN-1 (CCS1477)

(6S)-1 -(3,4-difluorophenyl)-6-{5-(3,5-dimethyl-1,2-oxazol-4-yl)-1 -[(1 r,4S)-4-methoxycyclohexyl]-1 H-benzimidazo!-2-yl)piperidin-2-one

Inobrodib

Inobrodib (CCS1477)

oral,inhibit,cancer,Epigenetic Reader Domain,nude,mice,CCS-1477,CCS1477,bromodomain,prostate,Inobrodib,Inhibitor,CCS 1477,proliferation,histones

CCS-1477 (CCS1477)

(S)-1-(3,4-difluorophenyl)-6-(5-(3,5-dimethylisoxazol-4-yl)-1-((1r,4S)-4-methoxycyclohexyl)-1H-benzo[d]imidazol-2-yl)piperidin-2-one

(S)-1-(3,4-Difluorophenyl)-6-(5-(3,5-dimethylisoxazol-4-yl)-1-(trans-4-methoxycyclohexyl)-1H-benzo[d]imidazol-2-yl)piperidin-2-one

Inobrodib, 10 mM in DMSO

Inobrodib (CCS-1477, CBP-IN-1)

(S)-1-(3,4-Difluorophenyl)-6-[5-(3,5-dimethyl-4-isoxazolyl)-1-(trans-4-methoxycyclohexyl)-2-benzimidazolyl]piperidin-2-one

2222941-37-7

C30H32F2N4O3