ChemicalBook > CAS DataBase List > SMARt-420
SMARt-420
- Product Name
- SMARt-420
- CAS No.
- 1616242-21-7
- Chemical Name
- SMARt-420
- Synonyms
- BDM41420;SMARt-420;SMARt-420 (BDM41420);SMARt-420 >=98% (HPLC);1-Butanone, 4,4,4-trifluoro-1-(3-phenyl-1-oxa-2,8-diazaspiro[4.5]dec-2-en-8-yl)-
- CBNumber
- CB85867378
- Molecular Formula
- C17H19F3N2O2
- Formula Weight
- 340.34
- MOL File
- 1616242-21-7.mol
More
Less
SMARt-420 Property
- Boiling point:
- 444.5±55.0 °C(Predicted)
- Density
- 1.31±0.1 g/cm3(Predicted)
- storage temp.
- 2-8°C
- solubility
- DMSO: 2mg/mL, clear
- pka
- 1.29±0.40(Predicted)
- form
- powder
- color
- white to beige
More
Less
SMARt-420 Chemical Properties,Usage,Production
Biological Activity
SMARt-420 (Small Molecule Aborting Resistance) activates an alternative bioactivation pathway of the tuberculosis antibiotic pro-drug ethionamide. Ethionamide bioactivation is normally catalyzed by monooxygenase EthA, but mutations in the enzyme have allowed many strains to become resistant. SMARt-420 activates a previously unknown pathway, reversing ethionamide-acquired resistance and clearing ethionamide-resistant infection in mice in addition to increasing the sensitivity of bacteria to ethionamide.
SMARt-420 Preparation Products And Raw materials
Raw materials
Preparation Products
More
Less
SMARt-420 Suppliers
- Tel
- 021-65675885 18964387627
- Fax
- 021-65675885
- info@efebio.com
- Country
- China
- ProdList
- 9804
- Advantage
- 58
- Tel
- 86-571-88216897,88216896 13588875226
- Fax
- 86-571-88216895
- sales@hzclap.com
- Country
- CHINA
- ProdList
- 6312
- Advantage
- 58
- Tel
- 021-58432009 400-005-6266
- Fax
- 021-58436166
- marketing1@energy-chemical.com
- Country
- China
- ProdList
- 44807
- Advantage
- 58
- Tel
- 0519-85524369
- 3477467573@qq.com
- Country
- China
- ProdList
- 8617
- Advantage
- 58
- Tel
- 025-85560043 15850508050
- Fax
- 025-85563444
- cindy.huang@synzest.com
- Country
- China
- ProdList
- 12000
- Advantage
- 58