3,4-Dimethylphenylboronic acid
- Product Name
- 3,4-Dimethylphenylboronic acid
- CAS No.
- 55499-43-9
- Chemical Name
- 3,4-Dimethylphenylboronic acid
- Synonyms
- AKOS BRN-0224;4-Borono-o-xylene;RARECHEM AH PB 0185;3,4-Dimethylphenylbo;3,4-Dimethylphenylboronicaci;3,4-diemthylphenylboronic acid;3,4-DIMETHYLPHENYLBORONIC ACID;3,4-DIMETHYLBENZENEBORONIC ACID;B-(3,4-DiMethylphenyl)boronic acid;3,4-Dimethylphenylboronic acid,97%
- CBNumber
- CB8668145
- Molecular Formula
- C8H11BO2
- Formula Weight
- 149.98
- MOL File
- 55499-43-9.mol
3,4-Dimethylphenylboronic acid Property
- Melting point:
- 220°C
- Boiling point:
- 304.9±52.0 °C(Predicted)
- Density
- 1.07±0.1 g/cm3(Predicted)
- storage temp.
- Keep in dark place,Sealed in dry,Room Temperature
- solubility
- soluble in Methanol
- form
- Powder
- pka
- 8.89±0.10(Predicted)
- color
- White to slightly beige
- BRN
- 2963858
- CAS DataBase Reference
- 55499-43-9(CAS DataBase Reference)
Safety
- Hazard Codes
- Xn,Xi
- Risk Statements
- 36/37/38-22-41-37/38
- Safety Statements
- 37/39-26-36/37-39
- HazardClass
- IRRITANT
- HS Code
- 29319090
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P405Store locked up.
N-Bromosuccinimide Price
- Product number
- D3110
- Product name
- 3,4-Dimethylphenylboronic Acid (contains varying amounts of Anhydride)
- Packaging
- 1g
- Price
- $58
- Updated
- 2025/07/31
- Product number
- D3110
- Product name
- 3,4-Dimethylphenylboronic Acid (contains varying amounts of Anhydride)
- Packaging
- 5g
- Price
- $212
- Updated
- 2025/07/31
- Product number
- D479928
- Product name
- 3,4-Dimethylphenylboronicacid
- Packaging
- 1g
- Price
- $55
- Updated
- 2021/12/16
- Product number
- AMTB1115
- Product name
- 3,4-Dimethylphenylboronicacid
- Packaging
- 25g
- Price
- $30
- Updated
- 2021/12/16
- Product number
- 6760-1-X1
- Product name
- 3,4-Dimethylbenzeneboronic acid
- Purity
- 98%
- Packaging
- 1g
- Price
- $49
- Updated
- 2021/12/16
3,4-Dimethylphenylboronic acid Chemical Properties,Usage,Production
Chemical Properties
Off-white Cryst
Uses
suzuki reaction
Synthesis
255837-23-1
55499-43-9
The general procedure for the synthesis of 3,4-dimethylphenylboronic acid from trifluoromethanesulfonic acid-3,4-dimethylphenyl ester is as follows: in a 50 mL round-bottomed flask (equipped with a side arm, condenser, and stirring bar) triphenylphosphine (0.131 g, 0.5 mmol, 20 mol%), p-iodoiodobenzene (0.585 g, 2.5 mmol), and triethylamine (1.78 mL, 12.5 mmol). The system was degassed by alternating vacuum and argon filling three times. Palladium dichloride (0.023 g, 0.13 mmol, 5 mol%) was added under positive argon atmosphere. After stirring at room temperature for 15 minutes, diisopropylaminoborane (5 mL, 1 M THF solution, 5 mmol) was added and again degassed by alternating vacuum and argon filling three times. The reaction mixture was heated to reflux and maintained at reflux for 12 hours. Upon completion of the reaction, it was cooled to 0 °C and methanol (6 mL, note: exothermic reaction accompanied by hydrogen release) was slowly added. Stirring was continued for 15 minutes, followed by concentration under reduced pressure to remove all solvent to give a black solid. The solid was dissolved in 3M sodium hydroxide solution (8 mL) and washed with hexane (3 x 10 mL). The aqueous phase was cooled to 0 °C (ice bath) and acidified with concentrated hydrochloric acid to pH ≤ 1, at which point 3,4-dimethylphenylboronic acid precipitated as a white solid. The aqueous phase was extracted with ether (3 x 10 mL), the organic phases were combined, dried with magnesium sulfate and filtered. Finally, the solvent was removed by concentration under reduced pressure to give the white solid product 3,4-dimethylphenylboronic acid.
References
[1] Tetrahedron, 2011, vol. 67, # 3, p. 576 - 583
3,4-Dimethylphenylboronic acid Preparation Products And Raw materials
Raw materials
Preparation Products
3,4-Dimethylphenylboronic acid Suppliers
- Tel
- 800-4238616
- Fax
- +1-888-520-1075 / +1-503-283-1987
- sales@tciamerica.com
- Country
- Americas
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- Advantage
- 75
View Lastest Price from 3,4-Dimethylphenylboronic acid manufacturers
- Product
- 3,4-Dimethylphenylboronic acid 55499-43-9
- Price
- US $34.00-1.20/kg
- Min. Order
- 1kg
- Purity
- 99%
- Supply Ability
- g-kg-tons, free sample is available
- Release date
- 2024-04-08
- Product
- 3,4-Dimethylphenylboronic acid 55499-43-9
- Price
- US $15.00-10.00/KG
- Min. Order
- 1KG
- Purity
- 99%+ HPLC
- Supply Ability
- Monthly supply of 1 ton
- Release date
- 2021-07-10
- Product
- 3,4-Dimethylphenylboronic acid 55499-43-9
- Price
- US $15.00-10.00/KG
- Min. Order
- 1KG
- Purity
- 99%+ HPLC
- Supply Ability
- Monthly supply of 1 ton
- Release date
- 2021-07-09