4-(TRIFLUOROMETHYL)PIPERIDINE
- Product Name
- 4-(TRIFLUOROMETHYL)PIPERIDINE
- CAS No.
- 657-36-3
- Chemical Name
- 4-(TRIFLUOROMETHYL)PIPERIDINE
- Synonyms
- 4-TrifluorMethylpiperidine;4-(TRIFLUOROMETHYL)PIPERIDINE;4-TrifluoroMethylpiperidine HCI;Piperidine, 4-(trifluoromethyl)-;4-(Trifluoromethyl)piperidine 97%
- CBNumber
- CB8670405
- Molecular Formula
- C6H10F3N
- Formula Weight
- 153.15
- MOL File
- 657-36-3.mol
4-(TRIFLUOROMETHYL)PIPERIDINE Property
- Melting point:
- 152-154°C
- Boiling point:
- 126-129°C
- Density
- 1.129±0.06 g/cm3(Predicted)
- refractive index
- 1.3910 to 1.3950
- storage temp.
- 2-8°C(protect from light)
- form
- Liquid
- pka
- 9.62±0.10(Predicted)
- color
- Colorless
- InChI
- InChI=1S/C6H10F3N/c7-6(8,9)5-1-3-10-4-2-5/h5,10H,1-4H2
- InChIKey
- RDRQUUWCJTYHCT-UHFFFAOYSA-N
- SMILES
- N1CCC(C(F)(F)F)CC1
Safety
- Hazard Codes
- N
- Risk Statements
- 36/37/38-50
- Safety Statements
- 26-36/37/39-61
- RIDADR
- 2735
- HazardClass
- 8
- PackingGroup
- Ⅲ
- HS Code
- 2933399990
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P405Store locked up.
N-Bromosuccinimide Price
- Product number
- T3081
- Product name
- 4-(Trifluoromethyl)piperidine
- Purity
- >97.0%(GC)(T)
- Packaging
- 1g
- Price
- $103
- Updated
- 2025/07/31
- Product number
- T3081
- Product name
- 4-(Trifluoromethyl)piperidine
- Purity
- >97.0%(GC)(T)
- Packaging
- 5g
- Price
- $309
- Updated
- 2025/07/31
- Product number
- T895548
- Product name
- 4-(Trifluoromethyl)piperidine
- Packaging
- 100mg
- Price
- $75
- Updated
- 2021/12/16
- Product number
- PC49502
- Product name
- 4-(Trifluoromethyl)piperidine
- Purity
- 97%
- Packaging
- 1g
- Price
- $61
- Updated
- 2021/12/16
- Product number
- PC49502
- Product name
- 4-(Trifluoromethyl)piperidine
- Purity
- 97%
- Packaging
- 5g
- Price
- $124
- Updated
- 2021/12/16
4-(TRIFLUOROMETHYL)PIPERIDINE Chemical Properties,Usage,Production
Uses
4-(Trifluoromethyl)piperidine is used in the preparation of retinoid-related orphan receptor inhibitors.
Synthesis
3796-24-5
657-36-3
GENERAL STEPS: An autoclave (Par 477) equipped with PID temperature control and kinetic measurement storage and a HEL 24 Cat reactor for substrate range testing were used as the reactor for the hydrogenation reaction. In standard experiments, the autoclave was placed in a glove box and the desired Rh NPs (1.25 or 0.625 mol%; catalyst concentration was calculated based on the total number of metallic Rh atoms on the NP surface) and the substrate (concentration of 0.124 M in THF) were added. Subsequently, molecular hydrogen was passed until the set pressure was reached and the reaction was stirred at the selected temperature for the desired time. Upon completion of the reaction, the autoclave was depressurized and the solution was filtered through silica gel for subsequent GC analysis. The conversion and selectivity of each reaction product was determined by GC-FID on an Agilent Technologies 7890A spectrometer using undecane as an internal standard on an HP-5 column (30 m × 0.25 mm × 0.25 μm).The TOF (conversion frequency) was defined as the number of moles of product generated per mole of Rh per hour on the NP surface.
References
[1] Journal of Catalysis, 2017, vol. 354, p. 113 - 127
4-(TRIFLUOROMETHYL)PIPERIDINE Preparation Products And Raw materials
Raw materials
Preparation Products
4-(TRIFLUOROMETHYL)PIPERIDINE Suppliers
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View Lastest Price from 4-(TRIFLUOROMETHYL)PIPERIDINE manufacturers
- Product
- 4-(TRIFLUOROMETHYL)PIPERIDINE 657-36-3
- Price
- US $0.00-0.00/KG
- Min. Order
- 1KG
- Purity
- 98.0%
- Supply Ability
- 10000KGS
- Release date
- 2025-07-07
- Product
- 4-Trifluoromethyl-piperidine 657-36-3
- Price
- US $3.00-9.00/KG
- Min. Order
- 0.1KG
- Purity
- 99%
- Supply Ability
- g-kg-tons, free sample is available
- Release date
- 2025-06-27
- Product
- 4-(Trifluoromethyl)piperidine 657-36-3
- Price
- US $0.00-0.00/kg
- Min. Order
- 1kg
- Purity
- 98%
- Supply Ability
- 1Ton
- Release date
- 2022-10-09