SALOR-INT L225193-1EA
- Product Name
- SALOR-INT L225193-1EA
- CAS No.
- 400863-77-6
- Chemical Name
- SALOR-INT L225193-1EA
- Synonyms
- SALOR-INT L225193-1EA;3-AMINO-N-(5-PHENYL-1,3,4-THIADIAZOL-2-YL)-6,7,8,9-TETRAHYDRO-5H-CYCLOHEPTA[B]THIENO[3,2-E]PYRIDINE-2-CARBOXAMIDE;5H-Cyclohepta[b]thieno[3,2-e]pyridine-2-carboxamide, 3-amino-6,7,8,9-tetrahydro-N-(5-phenyl-1,3,4-thiadiazol-2-yl)-;3-amino-6,7,8,9-tetrahydro-5H-1-thia-10-azacyclohepta[f]indene-2-carboxylic acid (5-phenyl-[1,3,4]thiadiazol-2-yl)amide
- CBNumber
- CB8674498
- Molecular Formula
- C21H19N5OS2
- Formula Weight
- 421.54
- MOL File
- 400863-77-6.mol
SALOR-INT L225193-1EA Property
- Density
- 1.437±0.06 g/cm3(Predicted)
- pka
- 5.09±0.50(Predicted)
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P321Specific treatment (see … on this label).
P332+P313IF SKIN irritation occurs: Get medical advice/attention.
P362Take off contaminated clothing and wash before reuse.
N-Bromosuccinimide Price
- Product number
- CHM0307262
- Product name
- 3-AMINO-N-(5-PHENYL-1,3,4-THIADIAZOL-2-YL)-6,7,8,9-TETRAHYDRO-5H-CYCLOHEPTA[B]THIENO[3,2-E]PYRIDINE-2-CARBOXAMIDE
- Purity
- 95.00%
- Packaging
- 5MG
- Price
- $496.25
- Updated
- 2021/12/16
SALOR-INT L225193-1EA Chemical Properties,Usage,Production
Description
ST-148 is a potent Dengue virus capsid inhibitor. ST-148-enhanced capsid protein self-interaction perturbs assembly and disassembly of DV nucleocapsids, probably by inducing structural rigidity.
Uses
ST-148 is a novel small molecule compound that has potent inhibitory effects against all four dengue virus serotypes. In the nonlethal AG129 mouse dengue virus infection model, ST-148 significantly reduced viremia and viral load in vital organs and tended to reduce plasma cytokine levels. Compound resistance was associated with the dengue virus capsid (C) gene, and the direct interaction of ST-148 with the C protein was presumed to be achieved through the protein's built-in fluorescence change in the presence of the compound. Therefore, ST-148 appears to interact with the dengue virus C protein and inhibit one or more unique steps of the viral replication cycle.
References
[1] A Novel Inhibitor of Dengue Virus Replication That Targets the Capsid Protein
SALOR-INT L225193-1EA Preparation Products And Raw materials
Raw materials
Preparation Products
SALOR-INT L225193-1EA Suppliers
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