IMIDAZOLE-D4

IMIDAZOLE-D4 Property

Melting point:

89-91 °C(lit.)

Boiling point:

256 °C(lit.)

Flash point:

145℃

form 

powder

pka

6.953(at 25℃)

CAS Number Unlabeled

288-32-4

Safety

Hazard Codes 

C,T

Risk Statements 

22-34-61

Safety Statements 

22-26-36/37/39-45-53

RIDADR 

UN 3259 8/PG 2

WGK Germany 

3

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Danger

Hazard statements

H302Harmful if swallowed

H314Causes severe skin burns and eye damage

Precautionary statements

P260Do not breathe dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P303+P361+P353IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

IMIDAZOLE-D4 Chemical Properties,Usage,Production

Uses

Imidazole-d₄ may be used in the synthesis of 1-ethylimidazole-d₈ by reacting with ethyl iodide-d₅ and 1-butylimidazole-d₁₂ by reacting with butyl iodide-d₉. These compounds form the precursors for the preparation of perdeuterated cellulose solvents, 1-ethyl-3-methylimidazolium acetate (EMIM-OAc-d₁₄) and 1-butyl-3-methylimidazolium acetate (BMIM-OAc-d₁₈).

Uses

Imidazole-d4 is a labelled imidazole, a versatile heterocycle used in the preparation of various biologically active compounds such as the amino acid histidine and is present in many antifungal medication. It is also used extensively as a corrosion inhibitor on transition metals such as copper.

General Description

Imidazole-d₄ is a deuterated NMR solvent useful in NMR-based research and analyses. Far-infrared spectrum of imidazole-d₄ in the range of 300-33-cm^-1 has been investigated.