MCA-ARG-PRO-PRO-GLY-PHE-SER-ALA-PHE-LYS(DNP)-OH

Product Name: MCA-ARG-PRO-PRO-GLY-PHE-SER-ALA-PHE-LYS(DNP)-OH
CAS No.: 323577-36-2
Chemical Name: MCA-ARG-PRO-PRO-GLY-PHE-SER-ALA-PHE-LYS(DNP)-OH
Synonyms: MCA-(ALA7,LYS(DNP)9)-BRADYKININ;MCA-ARG-PRO-PRO-GLY-PHE-SER-ALA-PHE-LYS(DNP)-OH;Mca-(Ala7,Lys(Dnp)9)-Bradykinin trifluoroacetate salt;7-Methoxycoumarin-4-acetyl [Ala7-(2,4-Dinitrophenyl)Lys9]-Bradykinin;Matrix metalloproteinases MMP FRET Substrate V, bradykinin Mca- (Ala?, Lys(Dnp)?;(7-methoxycoumarin-4-yl)acetyl-Arg-Pro-Pro-Gly-Phe-Ser-Ala-Phe-Lys-(2,4-dinitrophenyl);N2-[2-(7-Methoxy-2-oxo-2H-1-benzopyran-4-yl)acetyl]-L-arginyl-L-prolyl-L-prolylglycyl-L-phenylalanyl-L-seryl-L-alanyl-L-phenylalanyl-N6-(2,4-dinitrophenyl)-L-lysine;L-Lysine, N2-[2-(7-methoxy-2-oxo-2H-1-benzopyran-4-yl)acetyl]-L-arginyl-L-prolyl-L-prolylglycyl-L-phenylalanyl-L-seryl-L-alanyl-L-phenylalanyl-N6-(2,4-dinitrophenyl)-
CBNumber: CB8693396
Molecular Formula: C66H81N15O19
Formula Weight: 1388.44
MOL File: 323577-36-2.mol

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MCA-ARG-PRO-PRO-GLY-PHE-SER-ALA-PHE-LYS(DNP)-OH Property

Density: 1.48±0.1 g/cm3(Predicted)
storage temp.: -15°C
pka: 3.38±0.10(Predicted)
form: Solid
color: Light yellow to yellow
Appearance: White or Off-white Lyophilized Powder

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

American Custom Chemicals Corporation

Product number: PEP0009406
Product name: MCA-ARG-PRO-PRO-GLY-PHE-SER-ALA-PHE-LYS(DNP)-OH
Purity: 95.00%
Packaging: 5MG
Price: $501.9
Updated: 2021/12/16

Chem-Impex

Product number: 32995
Product name: Mca-(Ala7,Lys(Dnp)9)-Bradykinintrifluoroacetatesalt
Packaging: 1MG
Price: $523
Updated: 2021/12/16

Chem-Impex

Product number: 32995
Product name: Mca-(Ala7,Lys(Dnp)9)-Bradykinintrifluoroacetatesalt
Packaging: 5MG
Price: $2088.49
Updated: 2021/12/16

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MCA-ARG-PRO-PRO-GLY-PHE-SER-ALA-PHE-LYS(DNP)-OH Chemical Properties,Usage,Production

Description

Mca-(Ala7,Lys(Dnp)9)-Bradykinin is a very sensitive internally quenched fluorescent substrate for endothelin-converting enzyme-1 (ECE-1), a membrane-bound zinc metallopeptidase related to neprilysin in amino acid sequence. It is used as a substrate for insulin-degrading enzymes (IDE) and ACE2.

Uses

Mca-(ala7,lys(dnp)9)-bradykinin is a sensitive fluorogenic substrate for ECE-1 (endothelin-converting enzyme-1). The incorporation of a (7-methoxycoumarin-4-yl)acetyl (Mca) fluorescent group and a 2,4-dinitrophenyl (Dnp) quenching group has resulted in a large fluorescence increase upon substrate cleavage[1].

References

[1] Johnson GD, et al. Development of an internally quenched fluorescent substrate selective for endothelin-converting enzyme-1. Anal Biochem. 2000 Nov 1;286(1):112-8. DOI:10.1006/abio.2000.4772

Sequene

Mca-RPPGFSAFK(Dnp)

MCA-ARG-PRO-PRO-GLY-PHE-SER-ALA-PHE-LYS(DNP)-OH Preparation Products And Raw materials

Raw materials

Preparation Products

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MCA-ARG-PRO-PRO-GLY-PHE-SER-ALA-PHE-LYS(DNP)-OH Suppliers

China 41 United States 5 Global 46

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323577-36-2, MCA-ARG-PRO-PRO-GLY-PHE-SER-ALA-PHE-LYS(DNP)-OHRelated Search:

MCA-(ALA7,LYS(DNP)9)-BRADYKININ

MCA-ARG-PRO-PRO-GLY-PHE-SER-ALA-PHE-LYS(DNP)-OH

L-Lysine, N2-[2-(7-methoxy-2-oxo-2H-1-benzopyran-4-yl)acetyl]-L-arginyl-L-prolyl-L-prolylglycyl-L-phenylalanyl-L-seryl-L-alanyl-L-phenylalanyl-N6-(2,4-dinitrophenyl)-

N2-[2-(7-Methoxy-2-oxo-2H-1-benzopyran-4-yl)acetyl]-L-arginyl-L-prolyl-L-prolylglycyl-L-phenylalanyl-L-seryl-L-alanyl-L-phenylalanyl-N6-(2,4-dinitrophenyl)-L-lysine

(7-methoxycoumarin-4-yl)acetyl-Arg-Pro-Pro-Gly-Phe-Ser-Ala-Phe-Lys-(2,4-dinitrophenyl)

7-Methoxycoumarin-4-acetyl [Ala7-(2,4-Dinitrophenyl)Lys9]-Bradykinin

Matrix metalloproteinases MMP FRET Substrate V, bradykinin Mca- (Ala?, Lys(Dnp)?

Mca-(Ala7,Lys(Dnp)9)-Bradykinin trifluoroacetate salt

323577-36-2