2-METHYL-1-BUTANOL Property

Melting point:

-70 °C

Boiling point:

130 °C mm Hg(lit.)

Density 

0.815 g/mL at 25 °C(lit.)

vapor density 

3 (vs air)

vapor pressure 

3 mm Hg ( 20 °C)

refractive index 

n20/D 1.410±0.002(lit.)

Flash point:

110 °F(lit.)

CAS DataBase Reference

34713-94-5(CAS DataBase Reference)

Safety

Hazard Codes 

Xn

Risk Statements 

10-20-37-66

Safety Statements 

46

RIDADR 

UN 1105 3/PG 3

WGK Germany 

1

RTECS 

EL5250000

Toxicity

frog,LDLo,parenteral,2448mg/kg (2448mg/kg),PERIPHERAL NERVE AND SENSATION: SPASTIC PARALYSIS WITH OR WITHOUT SENSORY CHANGEBEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY),Archives Internationales de Pharmacodynamie et de Therapie. Vol. 50, Pg. 296, 1935.

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Danger

Hazard statements

H226Flammable liquid and vapour

H315Causes skin irritation

H318Causes serious eye damage

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P310Immediately call a POISON CENTER or doctor/physician.

P321Specific treatment (see … on this label).

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P362Take off contaminated clothing and wash before reuse.

2-METHYL-1-BUTANOL Chemical Properties,Usage,Production

Definition

ChEBI: 2-methylbutan-1-ol is a primary alcohol that is isopentane substituted by a hydroxy group at position 1. It has a role as a Saccharomyces cerevisiae metabolite. It is an alkyl alcohol and a primary alcohol. It derives from a hydride of an isopentane.

Purification Methods

Reflux the butanol with CaO, distil, reflux with magnesium and again fractionally distil it. A small sample of highly purified material is obtained by fractional crystallisation after conversion into a suitable ester such as the trinitrophthalate or the 3-nitrophthalate. The latter is converted to the cinchonine salt in acetone and recrystallised from CHCl3 by adding pentane. The salt is saponified, extracted with ether, and fractionally distilled. [Terry et al. J Chem Eng Data 5 403 1960, Beilstein 1 IV 1666.]