FURIN INHIBITOR II
- Product Name
- FURIN INHIBITOR II
- CAS No.
- 673202-67-0
- Chemical Name
- FURIN INHIBITOR II
- Synonyms
- H-(D)RRRRRR-NH2;HEXA-D-ARGININE;FURIN INHIBITOR II;Hexa-D-arginine aMide;Hexa-D-arginine,RRRRRR;Furin Inhibitor II, >98%;Furin Inhibitor II(Hexa-D-arginine);H-D-ARG-D-ARG-D-ARG-D-ARG-D-ARG-D-ARG-NH2;D-Argininamide,D-arginyl-D-arginyl-D-arginyl-D-arginyl-D-arginyl-;D-Argininamide, D-arginyl-D-arginyl-D-arginyl-D-arginyl-D-arginyl- (9CI)
- CBNumber
- CB8719126
- Molecular Formula
- C36H75N25O6
- Formula Weight
- 954.14
- MOL File
- 673202-67-0.mol
FURIN INHIBITOR II Property
- Density
- 1.59±0.1 g/cm3(Predicted)
- storage temp.
- Keep in dark place,Sealed in dry,Store in freezer, under -20°C
- solubility
- H2O : 50 mg/mL (52.40 mM; Need ultrasonic)DMSO : 5 mg/mL (5.24 mM; Need ultrasonic)
- form
- lyophilized
- pka
- 13.24±0.46(Predicted)
- color
- White to off-white
- Water Solubility
- Soluble to 2 mg/ml in water
Safety
- WGK Germany
- 3
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
- Precautionary statements
-
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P332+P313IF SKIN irritation occurs: Get medical advice/attention.
P337+P313IF eye irritation persists: Get medical advice/attention.
N-Bromosuccinimide Price
- Product number
- SCP0148
- Product name
- Furin Inhibitor II
- Packaging
- 5MG
- Price
- $268
- Updated
- 2023/06/20
- Product number
- 4711
- Product name
- Hexa-D-arginine
- Packaging
- 1
- Price
- $124
- Updated
- 2021/12/16
- Product number
- 145676
- Product name
- Hexa-D-arginine
- Packaging
- 1mg
- Price
- $375
- Updated
- 2021/12/16
- Product number
- H951018
- Product name
- Hexa-D-arginine
- Packaging
- 1mg
- Price
- $115
- Updated
- 2021/12/16
- Product number
- B5692
- Product name
- (R)-2-amino-5-((diaminomethylene)amino)-N-((6R,9R,12R,15R,18R)-1,1,23,23-tetraamino-6-carbamoyl-9,12,15-tris(3-((diaminomethylene)amino)propyl)-8,11,14,17-tetraoxo-2,7,10,13,16,22-hexaazatricosa-1,22-dien-18-yl)pentanamide
- Packaging
- 10mg
- Price
- $1020
- Updated
- 2021/12/16
FURIN INHIBITOR II Chemical Properties,Usage,Production
Uses
Furin Inhibitor II has been used as a furin inhibitor:
- to study its effects on transforming growth factor β1 (TGF-β1) induced glial cell line-derived neurotrophic factor (GDNF) production in non-tumorigenic immortalized human granulosa cell line (SVOG).
- to study its effect on cleavage of (Pro) renin receptor (PRR) induced by bovine serum albumin (BSA) in human kidney 2 (HK-2) cells.
- in furin cleavage assay.
General Description
Furin is a calcium-dependent serine endoproteinase and belongs to the subtilisin-like proprotein/prohormone convertase (PC) family. It is distributed ubiquitously and has a rhythmic movement between the trans-Golgi network, cell surface and the endosomes.
Biochem/physiol Actions
Furin plays a role in processing several pro-proteins such as, bone morphogenetic protein?4 (BMP-4), insulin receptor and Notch1 receptor. It also processes human immune deficiency virus 1 (HIV-1) glycoprotein gp160, several metalloproteases?and pro-β-nerve growth (pro-β-NGF) factor. Furin is also involved in cleaving transforming growth factor β1 (TGF-β1).
storage
Store at -20°C
FURIN INHIBITOR II Preparation Products And Raw materials
Raw materials
Preparation Products
FURIN INHIBITOR II Suppliers
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View Lastest Price from FURIN INHIBITOR II manufacturers
- Product
- FURIN INHIBITOR II 673202-67-0
- Price
- US $7.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 100kg
- Release date
- 2020-02-18