FURIN INHIBITOR II

Product Name: FURIN INHIBITOR II
CAS No.: 673202-67-0
Chemical Name: FURIN INHIBITOR II
Synonyms: H-(D)RRRRRR-NH2;HEXA-D-ARGININE;FURIN INHIBITOR II;Hexa-D-arginine aMide;Hexa-D-arginine,RRRRRR;Furin Inhibitor II, >98%;Furin Inhibitor II(Hexa-D-arginine);H-D-ARG-D-ARG-D-ARG-D-ARG-D-ARG-D-ARG-NH2;D-Argininamide,D-arginyl-D-arginyl-D-arginyl-D-arginyl-D-arginyl-;D-Argininamide, D-arginyl-D-arginyl-D-arginyl-D-arginyl-D-arginyl- (9CI)
CBNumber: CB8719126
Molecular Formula: C36H75N25O6
Formula Weight: 954.14
MOL File: 673202-67-0.mol

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FURIN INHIBITOR II Property

Density: 1.59±0.1 g/cm3(Predicted)
storage temp.: Keep in dark place,Sealed in dry,Store in freezer, under -20°C
solubility: H2O : 50 mg/mL (52.40 mM; Need ultrasonic)DMSO : 5 mg/mL (5.24 mM; Need ultrasonic)
form: lyophilized
pka: 13.24±0.46(Predicted)
Water Solubility: Soluble to 2 mg/ml in water

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Safety

WGK Germany: 3

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

Precautionary statements

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P337+P313IF eye irritation persists: Get medical advice/attention.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: SCP0148
Product name: Furin Inhibitor II
Packaging: 5MG
Price: $268
Updated: 2023/06/20

Tocris

Product number: 4711
Product name: Hexa-D-arginine
Packaging: 1
Price: $124
Updated: 2021/12/16

Usbiological

Product number: 145676
Product name: Hexa-D-arginine
Packaging: 1mg
Price: $375
Updated: 2021/12/16

TRC

Product number: H951018
Product name: Hexa-D-arginine
Packaging: 1mg
Price: $115
Updated: 2021/12/16

ApexBio Technology

Product number: B5692
Product name: (R)-2-amino-5-((diaminomethylene)amino)-N-((6R,9R,12R,15R,18R)-1,1,23,23-tetraamino-6-carbamoyl-9,12,15-tris(3-((diaminomethylene)amino)propyl)-8,11,14,17-tetraoxo-2,7,10,13,16,22-hexaazatricosa-1,22-dien-18-yl)pentanamide
Packaging: 10mg
Price: $1020
Updated: 2021/12/16

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FURIN INHIBITOR II Chemical Properties,Usage,Production

Uses

Furin Inhibitor II has been used as a furin inhibitor:

to study its effects on transforming growth factor β1 (TGF-β1) induced glial cell line-derived neurotrophic factor (GDNF) production in non-tumorigenic immortalized human granulosa cell line (SVOG).
to study its effect on cleavage of (Pro) renin receptor (PRR) induced by bovine serum albumin (BSA) in human kidney 2 (HK-2) cells.
in furin cleavage assay.

General Description

Furin is a calcium-dependent serine endoproteinase and belongs to the subtilisin-like proprotein/prohormone convertase (PC) family. It is distributed ubiquitously and has a rhythmic movement between the trans-Golgi network, cell surface and the endosomes.

Biochem/physiol Actions

Furin plays a role in processing several pro-proteins such as, bone morphogenetic protein?4 (BMP-4), insulin receptor and Notch1 receptor. It also processes human immune deficiency virus 1 (HIV-1) glycoprotein gp160, several metalloproteases?and pro-β-nerve growth (pro-β-NGF) factor. Furin is also involved in cleaving transforming growth factor β1 (TGF-β1).

storage

Store at -20°C

FURIN INHIBITOR II Preparation Products And Raw materials

Raw materials

Preparation Products

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FURIN INHIBITOR II Suppliers

China 58 United Kingdom 2 United States 10 Global 70

Shanghai Hanhong Scientific Co.,Ltd.

Tel
Country: China
ProdList: 42982
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Chemsky (shanghai) International Co.,Ltd

Tel: 021-50135380
Email: shchemsky@sina.com
Country: China
ProdList: 15421
Advantage: 60

MedChemexpress LLC

Tel: 021-58955995
Fax: 609-228-5909
Email: sales@medchemexpress.cn
Country: United States
ProdList: 4863
Advantage: 58

Wuxi Zhongkun Biochemical Technology Co., Ltd.

Tel: 0510-85629785 18013409632
Fax: 051085625359
Email: sales@reading-chemicals.com
Country: China
ProdList: 15185
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Sigma-Aldrich

Tel: 021-61415566 800-8193336
Email: orderCN@merckgroup.com
Country: China
ProdList: 51471
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Creative Peptides

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Email: info@creative-peptides.com
Country: United States
ProdList: 6084
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Nanjing Leon Biological Technology Co., Ltd.

Tel: 17705183659
Fax: 84523390
Email: sales@njleonbiotech.com
Country: China
ProdList: 5503
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Nanjing Peptide Biotech Ltd.

Tel: 025-58361106-805 13082558573
Fax: 025-58361106-806
Email: liugang@njpeptide.com
Country: China
ProdList: 9961
Advantage: 55

Hangzhou Peptidego Biotech Co.,Ltd.

Tel: 0571-87213919
Fax: 0571-87213919
Email: eric@peptidego.com
Country: China
ProdList: 6347
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Nanjing Meihao Pharmaceutical Technology Co., Ltd.

Tel: meitaochem@126.com
Email: meitaochem@126.com
Country: China
ProdList: 19105
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View Lastest Price from FURIN INHIBITOR II manufacturers

Career Henan Chemical Co

Product: FURIN INHIBITOR II 673202-67-0
Price: US $7.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 100kg
Release date: 2020-02-18

673202-67-0, FURIN INHIBITOR IIRelated Search:

H-GLU-LEU-ASP-[(2R,4S,5S)-5-AMINO-4-HYDROXY-2,7-DIMETHYL-OCTANOYL]-VAL-GLU-PHE-GLY-GLY-D-ARG-D-ARG-D-ARG-D-ARG-D-ARG-D-ARG-D-ARG-D-ARG-D-ARG-OH FURIN INHIBITOR II C(NPYS)RRRRRRRRR-NH2

HEXA-D-ARGININE

H-(D)RRRRRR-NH2

FURIN INHIBITOR II

H-D-ARG-D-ARG-D-ARG-D-ARG-D-ARG-D-ARG-NH2

Hexa-D-arginine aMide

D-ArgininamideD-arginyl-D-arginyl-D-arginyl-D-arginyl-D-arginyl-D-alanine

Furin Inhibitor II, >98%

Hexa-D-arginine,RRRRRR

D-Argininamide, D-arginyl-D-arginyl-D-arginyl-D-arginyl-D-arginyl- (9CI)

D-Argininamide,D-arginyl-D-arginyl-D-arginyl-D-arginyl-D-arginyl-

inhibit,furin,Furin Inhibitor II,TNF-α,PACE4,noncytotoxic,PC1,anthrax,PEA,HexaDarginine,Hexa D arginine,exotoxins,Inhibitor

Furin Inhibitor II(Hexa-D-arginine)

673202-67-0

C36H75N25O6