TYR-GLY-SER-LEU-PRO-GLN-LYS-SER-GLN-ARG-SER-GLN-ASP-GLU-ASN

ChemicalBook > CAS DataBase List > TYR-GLY-SER-LEU-PRO-GLN-LYS-SER-GLN-ARG-SER-GLN-ASP-GLU-ASN

TYR-GLY-SER-LEU-PRO-GLN-LYS-SER-GLN-ARG-SER-GLN-ASP-GLU-ASN

Product Name: TYR-GLY-SER-LEU-PRO-GLN-LYS-SER-GLN-ARG-SER-GLN-ASP-GLU-ASN
CAS No.: 98474-59-0
Chemical Name: TYR-GLY-SER-LEU-PRO-GLN-LYS-SER-GLN-ARG-SER-GLN-ASP-GLU-ASN
Synonyms: des-Gly77;MYELIN BASIC PROTEIN, FRAGMENT 68-82;MYELIN BASIC PROTEIN (68-82), GUINEA PIG;(Des-Gly77,Des-His78)-MBP (68-84) (bovine);MYELIN BASIC PROTEIN MBP (68-82), GUINEA PIG;MYELIN BASIC PROTEIN FRAGMENT 68-82 GUINEA PIG;myelin basic protein guinea pig fragment 68-82;(Des-Gly77,Des-His78)-MBP (68-84) (guinea pig);MBP (68-82),Myelin Basic Protein (68-84), guinea pig;DES[GLY77,HIS78]-MYELIN BASIC PROTEIN, FRAGMENT 68-64
CBNumber: CB8721158
Molecular Formula: C71H113N23O28
Formula Weight: 1736.81
MOL File: 98474-59-0.mol

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TYR-GLY-SER-LEU-PRO-GLN-LYS-SER-GLN-ARG-SER-GLN-ASP-GLU-ASN Property

storage temp.: -20°C
solubility: insoluble in EtOH; ≥173.6 mg/mL in DMSO; ≥54.6 mg/mL in H2O
form: solid
color: White to off-white
biological source: guinea pig
Sequence: H-Tyr-Gly-Ser-Leu-Pro-Gln-Lys-Ser-Gln-Arg-Ser-Gln-Asp-Glu-Asn-OH

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Safety

WGK Germany: 3

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: M3755
Product name: Myelin Basic Protein Guinea Pig Fragment 68-82
Purity: ≥97% (HPLC)
Packaging: 1mg
Price: $493.8
Updated: 2024/03/01

Alfa Aesar

Product number: J66176
Product name: Des-[Gly77, His78] Myelin Basic Protein (68-84), bovine
Packaging: 1mg
Price: $109
Updated: 2021/12/16

ApexBio Technology

Product number: A1031
Product name: MyelinBasicProtein(68-82),guineapig
Packaging: 10mg
Price: $110
Updated: 2021/12/16

ApexBio Technology

Product number: A1031
Product name: MyelinBasicProtein(68-82),guineapig
Packaging: 25mg
Price: $154
Updated: 2021/12/16

ApexBio Technology

Product number: A1031
Product name: MyelinBasicProtein(68-82),guineapig
Packaging: 5mg
Price: $66
Updated: 2021/12/16

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TYR-GLY-SER-LEU-PRO-GLN-LYS-SER-GLN-ARG-SER-GLN-ASP-GLU-ASN Chemical Properties,Usage,Production

Uses

Myelin Basic Protein Guinea Pig Fragment 68-82 has been used for lymphocyte activation in human blood samples. It has also been used as a component of the incomplete Freundμs adjuvant for the induction of autoimmune encephalomyelitis in rats.

Biological Activity

myelin basic protein (68-82), guinea pig,(c71h113n23o28) is a peptide with the sequence tyr-gly-ser-leu-pro-gln-lys-ser-gln-arg-ser-gln-asp-glu-asn, mw= 1736.79. myelin basic protein (mbp) is a protein believed to be important in the process of myelination of nerves in the nervous system. knockout mice deficient in mbp showed decreased amounts of cns myelination and have developed a progressive disorder characterized by tremors, seizures, and early death. mbp research has centered on its role in demyelinating diseases, in particular, multiple sclerosis (ms). several studies have uncovered the role of antibodies against mbp in the pathogenesis of ms.] some studies have linked a genetic predisposition to ms to the mbp gene, though a majority have not. some recent work has shown that inoculating an animal with mbp to generate an immune response against it increases blood–brain barrier permeability.figure1 formula of myelin basic protein (68-82), guinea pigfigure2 structure of myelin basic protein

Biochem/physiol Actions

Myelin basic protein fragment that induces experimental allergic encephalomyelitis.

References

1. Sakamoto Y, Kitamura K, Yoshimura K, Nishijima T, Uyemura K (March 1987). "Complete amino acid sequence of POprotein in bovine peripheral nerve myelin". J. Biol. Chem. 262 (9): 4208–14.2. Deber CM, Reynolds SJ (April 1991). "Central nervous system myelin: structure, function, and pathology". Clin. Biochem. 24 (2): 113–34.3. Inouye H, Kirschner DA (January 1991). "Folding and function of the myelin proteins from primary sequence data". J. Neurosci. Res. 28 (1): 1–17.4. Berger T, Rubner P, Schautzer F, Egg R, Ulmer H, Mayringer I, Dilitz E, Deisenhammer F, Reindl M (July 2003). "Antimyelin antibodies as a predictor of clinically definite multiple sclerosis after a first demyelinating event". N. Engl. J. Med. 349 (2): 139–45.

TYR-GLY-SER-LEU-PRO-GLN-LYS-SER-GLN-ARG-SER-GLN-ASP-GLU-ASN Preparation Products And Raw materials

Raw materials

Preparation Products

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TYR-GLY-SER-LEU-PRO-GLN-LYS-SER-GLN-ARG-SER-GLN-ASP-GLU-ASN Suppliers

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View Lastest Price from TYR-GLY-SER-LEU-PRO-GLN-LYS-SER-GLN-ARG-SER-GLN-ASP-GLU-ASN manufacturers

Career Henan Chemical Co

Product: TYR-GLY-SER-LEU-PRO-GLN-LYS-SER-GLN-ARG-SER-GLN-ASP-GLU-ASN 98474-59-0
Price: US $1.00/g
Min. Order: 1g
Purity: ≥98%
Supply Ability: g/kg/Ton
Release date: 2020-03-05

98474-59-0, TYR-GLY-SER-LEU-PRO-GLN-LYS-SER-GLN-ARG-SER-GLN-ASP-GLU-ASNRelated Search:

C-reactive protein Alkaline Peptone Water Inositol Basic protease H-GLY-GLU-GLY-OH GLYCYL-DL-ASPARAGINE H-GLY-ASN-OH H-GLU-ALA-OH DL-ALANYL-DL-ASPARAGINE TYR-GLY-SER-LEU-PRO-GLN-LYS-SER-GLN-ARG-SER-GLN-ASP-GLU-ASN 4,4-BIS(N,N-DIBUTYRIC ACID) H-ALA-ASN-OH N-Acetyl-L-asparagine

H-TYR-GLY-SER-LEU-PRO-GLN-LYS-ALA-GLN-ARG-PRO-GLN-ASP-GLU-ASN-OH

H-TYR-GLY-SER-LEU-PRO-GLN-LYS-SER-GLN-ARG-SER-GLN-ASP-GLU-ASN-OH

(DES-GLY77,DES-HIS78)-MYELIN BASIC PROTEIN (68-84) (BOVINE)

(DES-GLY77,DES-HIS78)-MYELIN BASIC PROTEIN (68-84) (GUINEA PIG)

DES-GLY77, DES-HIS78-MYELIN BASIC PROTEIN FRAGMENT 68-84 BOVINE

DES-[GLY77,HIS78] MYELIN BASIC PROTEIN (68-84), BOVINE

DES[GLY77,HIS78]-MYELIN BASIC PROTEIN, FRAGMENT 68-64

DES[GLY77, HIS78]-SER75,80-MYELIN BASIC PROTEIN BOVINE FRAGMENT 68-84

TYR-GLY-LEU-PRO-GLN-LYS-SER-GLN-ARG-SER-GLN-ASP-GLU-ASN

TYR-GLY-SER-LEU-PRO-GLN-LYS-ALA-GLN-ARG-PRO-GLN-ASP-GLU-ASN

TYR-GLY-SER-LEU-PRO-GLN-LYS-SER-GLN-ARG-SER-GLN-ASP-GLU-ASN

MYELIN BASIC PROTEIN, FRAGMENT 68-82

MYELIN BASIC PROTEIN FRAGMENT 68-82 GUINEA PIG

MYELIN BASIC PROTEIN (68-82), GUINEA PIG

des-gly77, des-his78-myelin basic protein bovine fragment 68-84

myelin basic protein guinea pig fragment 68-82

DES-GLY77, HIS78-MYELIN BASIC PROTEIN FRAGMENT 68-84 BOVINE

MYELIN BASIC PROTEIN MBP (68-82), GUINEA PIG

myelin, basic protein, fragment 68-84, des-Gly77, his78

des-Gly77

des-His78-Myelin Basic Protein Bovine fragment 68-84

(Des-Gly77,Des-His78)-Myelin Basic Protein (68-84) (guinea pig) (Des-Gly77,Des-His78)-MBP (68-84) (guinea pig)

(Des-Gly77,Des-His78)-MBP (68-84) (bovine)

(Des-Gly77,Des-His78)-MBP (68-84) (guinea pig)

L-Tyrosylglycyl-L-seryl-L-leucyl-L-prolyl-L-glutaminyl-L-lysyl-L-seryl-L-glutaminyl-L-arginyl-L-seryl-L-glutaminyl-L-alpha-aspartyl-L-alpha-glutamyl-L-asparagine

Myelin basic protein guinea pig fragment 68-82, ≥97% (HPLC)

(Des-Gly77,Des-His78)-Myelin Basic Protein (68-84) (guinea pig) H-Tyr-Gly-Ser-Leu-Pro-Gln-Lys-Ser-Gln-Arg-Ser-Gln-Asp-Glu-Asn-OH

TYR-GLY-SER-LEU-PRO-GLN-LYS-SER-GLN-ARG-SER-GLN-ASP-GLU-ASN USP/EP/BP

Myelin Basic Protein (MBP) (68-82), guinea pig,Inhibitor,inhibit,Myelin Basic Protein (MBP) (68 82), guinea pig,Myelin Basic Protein (MBP) (6882), guinea pig

MBP (68-82),Myelin Basic Protein (68-84), guinea pig

98474-59-0

C73H115N23O26

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