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PROPARGYLALDEHYDE DIETHYL ACETAL

Uses
Product Name
PROPARGYLALDEHYDE DIETHYL ACETAL
CAS No.
10160-87-9
Chemical Name
PROPARGYLALDEHYDE DIETHYL ACETAL
Synonyms
3,3-Diethoxyprop-1-yne;3,3-DIETHOXY-1-PROPYNE;3,3-DIETHOXYPROPYNE;3,3-dimethoxyprop-1-yne;PROPIOLALDEHYDE DIETHYL ACETAL;1-Propyne, 3,3-diethoxy-;3,3-Diethoxy-1-propyne~Propargylaldehyde diethyl acetal;NSC 45019;(C2H5O)2CHC≡CH;TIMTEC-BB SBB008980
CBNumber
CB8724715
Molecular Formula
C7H12O2
Formula Weight
128.17
MOL File
10160-87-9.mol
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PROPARGYLALDEHYDE DIETHYL ACETAL Property

Boiling point:
138-139.5 °C(lit.)
Density 
0.894 g/mL at 25 °C(lit.)
refractive index 
n20/D 1.412(lit.)
Flash point:
90 °F
storage temp. 
2-8°C
solubility 
Chloroform, Methanol (Slightly)
form 
Liquid
Specific Gravity
0.894
color 
Clear light yellow
Water Solubility 
Slightly soluble in water.
BRN 
1701566
Stability:
Light Sensitive, Volatile
InChI
InChI=1S/C7H12O2/c1-4-7(8-5-2)9-6-3/h1,7H,5-6H2,2-3H3
InChIKey
RGUXEWWHSQGVRZ-UHFFFAOYSA-N
SMILES
C#CC(OCC)OCC
CAS DataBase Reference
10160-87-9(CAS DataBase Reference)
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Safety

Hazard Codes 
Xi
Risk Statements 
10-36/37/38
Safety Statements 
16-26-36
RIDADR 
UN 1993 3/PG 3
WGK Germany 
3
21
HazardClass 
3
PackingGroup 
III
HS Code 
29110000
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H226Flammable liquid and vapour

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P210Keep away from heat/sparks/open flames/hot surfaces. — No smoking.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
303607
Product name
3,3-Diethoxy-1-propyne
Purity
97%
Packaging
1g
Price
$64.8
Updated
2023/06/20
Sigma-Aldrich
Product number
303607
Product name
3,3-Diethoxy-1-propyne
Purity
97%
Packaging
5g
Price
$217
Updated
2023/06/20
TCI Chemical
Product number
P1173
Product name
Propargylaldehyde Diethyl Acetal
Purity
>97.0%(GC)
Packaging
5mL
Price
$106
Updated
2025/07/31
TCI Chemical
Product number
P1173
Product name
Propargylaldehyde Diethyl Acetal
Purity
>97.0%(GC)
Packaging
25mL
Price
$351
Updated
2025/07/31
TRC
Product number
P757800
Product name
Propargylaldehyde Diethyl Acetal
Packaging
1g
Price
$45
Updated
2021/12/16
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PROPARGYLALDEHYDE DIETHYL ACETAL Chemical Properties,Usage,Production

Uses

Propargylaldehyde diethyl acetal is a useful reactant for the synthesis of alkenylsilanes via radical stereoselective hydrosilylation of alkynes with the help of Eosin Y and thiols as catalysts.

Chemical Properties

Clear light yellow liquid

Uses

Propargylaldehyde diethyl acetal is a useful reactant for the synthesis of alkenylsilanes via radical stereoselective hydrosilylation of alkynes with the help of Eosin Y and thiols as catalysts.

Synthesis Reference(s)

Tetrahedron Letters, 17, p. 4723, 1976 DOI: 10.1016/S0040-4039(00)93007-7

Synthesis

5221-17-0

64-17-5

10160-87-9

General procedure for the synthesis of 3,3-diethoxyprop-1-yne from 2,3-dibromopropanal and ethanol: (2) Addition of sodium hydroxide to the anhydrous ethanol solution obtained in step (1). This was done by dissolving 155 kg of sodium hydroxide in 470 kg of anhydrous ethanol to prepare an anhydrous ethanol solution of sodium hydroxide, and refluxing the reaction mixture at 82 °C for 10 min. Upon completion of the reaction, separation and purification operations were carried out to obtain propargyl acetal diethyl acetal. First, the isolation and purification was carried out at 20 °C to remove solid impurities by centrifugation, followed by soaking in 80 kg of ethanol in a filter for 10 min, after which it was dried. The filtrate was transferred to a distillation flask and first distilled at atmospheric pressure until the temperature reached 100°C and the fractions were collected. Subsequently, decompression distillation was started, gradually increasing the vacuum to -0.09 MPa and maintaining the bottom temperature at 100 °C until the heating was stopped. Next, atmospheric distillation was carried out by setting the reflux ratio to 4:1, using a 600 mm packed column and controlling the bottom temperature at 120 °C. After distillation, the organic phases were combined and stirred with 10 kg of sodium hydroxide for 1 h, followed by filtration. The filtrate was added to the distillation unit and distilled under a vacuum of -0.097 MPa using a 600 mm distillation column with a set reflux ratio of 4:1. When the bottom temperature reached 50°C and the fraction temperature reached 42°C, the qualified product was collected. Finally, 60kg of qualified products with content >98% and moisture <0.1% were obtained.

References

[1] Patent: CN106749127, 2017, A. Location in patent: Paragraph 0057; 0061-0064; 0081; 0089-0094; 0115; 0119-0122

PROPARGYLALDEHYDE DIETHYL ACETAL Preparation Products And Raw materials

Raw materials

Preparation Products

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PROPARGYLALDEHYDE DIETHYL ACETAL Suppliers

Cool Pharm, Ltd
Tel
021-60455363 18019463053
Fax
50966098
Email
sales@coolpharm.com
Country
China
ProdList
12346
Advantage
58
Taizhou Jiecheng Chemical Co., Ltd.
Tel
15868606025
Email
2598306141@qq.com
Country
China
ProdList
96
Advantage
55
Henan Aosman Biotechnology Co., LTD
Tel
0371-0371-61318675 17719817155
Fax
0371-61318675
Email
sales@xlinebio.com
Country
China
ProdList
2857
Advantage
58
Ningbo Zhenlei Chemical Co.,ltd.
Tel
0576-0576-88203603 15867601896
Fax
+0576-88203603
Email
julie.xiang@zhenleichem.com
Country
China
ProdList
122
Advantage
58
Henan Chongyi Biomedicine Co., Ltd
Tel
13566934155 18257818007;
Fax
QQ1571202295
Email
779340002@qq.com
Country
China
ProdList
41
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58
J & K SCIENTIFIC LTD.
Tel
18210857532; 18210857532
Fax
86-10-82849933
Email
jkinfo@jkchemical.com
Country
China
ProdList
96815
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76
Meryer (Shanghai) Chemical Technology Co., Ltd.
Tel
4006356688 18621169109
Fax
86-21-61259102
Email
market03@meryer.com
Country
China
ProdList
40228
Advantage
62
Beijing Donghualituo Techonlogy Development Co.,Ltd.
Tel
010-88425576
Fax
(+86)-10-88425546
Email
sales@dhltchem.com
Country
China
ProdList
793
Advantage
59
Alfa Aesar
Tel
400-6106006
Fax
021-67582001/03/05
Email
saleschina@alfa-asia.com
Country
China
ProdList
30123
Advantage
84
TCI (Shanghai) Development Co., Ltd.
Tel
021-67121386
Fax
021-67121385
Email
Sales-CN@TCIchemicals.com
Country
China
ProdList
24529
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81
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View Lastest Price from PROPARGYLALDEHYDE DIETHYL ACETAL manufacturers

Zhuozhou Wenxi import and Export Co., Ltd
Product
PROPARGYLALDEHYDE DIETHYL ACETAL 10160-87-9
Price
US $15.00-10.00/KG
Min. Order
1KG
Purity
99%+ HPLC
Supply Ability
Monthly supply of 1 ton
Release date
2021-07-10
Zhuozhou Wenxi import and Export Co., Ltd
Product
PROPARGYLALDEHYDE DIETHYL ACETAL 10160-87-9
Price
US $15.00-10.00/KG
Min. Order
1KG
Purity
99%+ HPLC
Supply Ability
Monthly supply of 1 ton
Release date
2021-07-08
Longyan Tianhua Biological Technology Co., Ltd
Product
PROPARGYLALDEHYDE DIETHYL ACETAL 10160-87-9
Price
US $20.00/KG
Min. Order
1KG
Purity
99
Supply Ability
999
Release date
2020-10-27

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