Description Structure Properties Regulation of synthesis and release Discovery Biological functions
ChemicalBook > CAS DataBase List > CORAZONIN

CORAZONIN

Description Structure Properties Regulation of synthesis and release Discovery Biological functions
Product Name
CORAZONIN
CAS No.
122929-08-2
Chemical Name
CORAZONIN
Synonyms
CORAZONIN;PYR-TFQYSRGWTN-NH2;CORAZONIN,CORAZONI;CORAZONIN USP/EP/BP;Corazonin, ≥97% (HPLC);Corazonin (Bombyx mori);Black-inducing neuropeptide;Corazonin (Neobellieria bullata);CORAZONIN (PERIPLANETA AMERICANA);PYR-THR-PHE-GLN-TYR-SER-ARG-GLY-TRP-THR-ASN-NH2
CBNumber
CB8738433
Molecular Formula
C62H84N18O18
Formula Weight
1369.44
MOL File
122929-08-2.mol
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CORAZONIN Property

Density 
1.56±0.1 g/cm3(Predicted)
storage temp. 
−20°C
pka
9.82±0.15(Predicted)
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Safety

WGK Germany 
3
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Usbiological
Product number
C7900-60
Product name
Corazonin
Packaging
5mg
Price
$257
Updated
2021/12/16
Biosynth Carbosynth
Product number
FC110272
Product name
Corazonin Pyr-Thr-Phe-Gln-Tyr-Ser-Arg-Gly-Trp-Thr-Asn-NH2
Packaging
1mg
Price
$131
Updated
2021/12/16
Biosynth Carbosynth
Product number
FC110272
Product name
Corazonin Pyr-Thr-Phe-Gln-Tyr-Ser-Arg-Gly-Trp-Thr-Asn-NH2
Packaging
2mg
Price
$228
Updated
2021/12/16
Biosynth Carbosynth
Product number
FC110272
Product name
Corazonin Pyr-Thr-Phe-Gln-Tyr-Ser-Arg-Gly-Trp-Thr-Asn-NH2
Packaging
5mg
Price
$456
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
PEP0001152
Product name
CORAZONIN
Purity
95.00%
Packaging
1MG
Price
$606.62
Updated
2021/12/16
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CORAZONIN Chemical Properties,Usage,Production

Description

A highly conserved neuropeptide produced by the central nervous system in insects, crustaceans, and ticks, CRZ has been implicated in controlling different species- and stage-specific functions.

Structure

Corazonin is a very conserved N-terminally blocked undecapeptide amidated at the C-terminus. The aa sequence is conserved in all examined arthropods (insects, crustaceans, and ticks). Corazonin is distantly related to the vertebrate gonadotropinreleasing hormone (GnRH) and the GnRH-like peptide from mollusks.

Properties

Corazonin:Mr 1350–1370; soluble in water, physiological saline, and 50%–70% methanol or ethanol.

Regulation of synthesis and release

Corazonin expression appears to be constitutive. In locusts, external environmental conditions such as high population density and low temperature seem to elicit corazonin secretion from the CC.In D. melanogaster, corazonin is centrally released from the abdominal interneurons during mating.

Discovery

Corazonin was isolated as a cardioactive peptide from the corpora cardiaca (CC) of the cockroach Periplaneta americana, and subsequently identified in many arthropods. This neuropeptide controls cuticle melanization in locusts and crayfish, initiation of the ecdysis sequence in moths, and modulation of stress responses and male reproduction in flies.

Biological functions

Corazonin stimulates the heartbeat in P. americana and Rhodnius prolixus in vitro, but is inactive in vivo and in other insects.Corazonin controls eye pigment migration, melanization of the cuticle, and a shift to the gregarious phase in locusts.In the crustacean Procambarus clarkii, it regulates chromatophore migration in the integument.

CORAZONIN Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from CORAZONIN manufacturers

Career Henan Chemical Co
Product
CORAZONIN 122929-08-2
Price
US $1.00/g
Min. Order
1g
Purity
≥98%
Supply Ability
g/kg/Ton
Release date
2020-03-05

122929-08-2, CORAZONINRelated Search:


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