4-Bromo-3,5-dimethyl-benzonitrile
- Product Name
- 4-Bromo-3,5-dimethyl-benzonitrile
- CAS No.
- 75344-77-3
- Chemical Name
- 4-Bromo-3,5-dimethyl-benzonitrile
- Synonyms
- 5-DIMETHYL-BENZONITRILE;2-Bromo-5-cyano-m-xylene;3,5-Dimethyl-4-bromobenzonitrile;4-BROMO-3,5-DIMETHYL-BENZONITRILE;Benzonitrile,4-bromo-3,5-dimethyl-;4-Bromo-3,5-dimethylbenzonitrile 98%;4-BroMo-3,5-diMethylbenzonitrile, 97%+;4-Bromo-3,5-dimethyl-benzonitrile, CAS 75344-77-3;4-BROMO-3,5-DIMETHY4-BROMO-3,5-DIMETHYL-BENZONITRILEL-BENZONITRILE
- CBNumber
- CB8743996
- Molecular Formula
- C9H8BrN
- Formula Weight
- 210.07
- MOL File
- 75344-77-3.mol
4-Bromo-3,5-dimethyl-benzonitrile Property
- Melting point:
- 135-137℃
- Boiling point:
- 291℃
- Density
- 1.44
- Flash point:
- 130℃
- storage temp.
- Sealed in dry,Room Temperature
- Appearance
- White to off-white Solid
- InChI
- InChI=1S/C9H8BrN/c1-6-3-8(5-11)4-7(2)9(6)10/h3-4H,1-2H3
- InChIKey
- AVXHSMPHQGFXRG-UHFFFAOYSA-N
- SMILES
- C(#N)C1=CC(C)=C(Br)C(C)=C1
Safety
- HS Code
- 2926907090
N-Bromosuccinimide Price
- Product number
- B691578
- Product name
- 4-Bromo-3,5-dimethylbenzonitrile
- Packaging
- 100mg
- Price
- $45
- Updated
- 2021/12/16
- Product number
- B691578
- Product name
- 4-Bromo-3,5-dimethylbenzonitrile
- Packaging
- 500mg
- Price
- $65
- Updated
- 2021/12/16
- Product number
- 075040
- Product name
- 4-Bromo-3,5-dimethylbenzonitrile
- Purity
- 95+%
- Packaging
- 1g
- Price
- $100
- Updated
- 2021/12/16
- Product number
- FB31344
- Product name
- 4-Bromo-3,5-dimethylbenzonitrile
- Packaging
- 5G
- Price
- $100
- Updated
- 2021/12/16
- Product number
- 3737-9-04
- Product name
- 4-Bromo-3,5-dimethylbenzonitrile
- Packaging
- 5G
- Price
- $180
- Updated
- 2021/12/16
4-Bromo-3,5-dimethyl-benzonitrile Chemical Properties,Usage,Production
Synthesis
35510-00-0
75344-77-3
General procedure for the synthesis of 4-bromo-3,5-dimethylbenzonitrile from 2-bromo-5-(bromomethyl)-1,3-xylene: 2-bromo-5-(bromomethyl)-1,3-xylene (0.9 g, 3.24 mmol) was added to a 100 mL three-necked flask at room temperature. Ammonium hydroxide (4.41 g, 64.8 mmol) and iodine (0.8 g, 6.28 mmol) were added slowly under stirring. The reaction mixture was heated to 60 °C in acetonitrile (9 mL) under nitrogen protection and kept at this temperature for 4 hours. The progress of the reaction was monitored by TLC and the heating was stopped after confirming the complete reaction of the ingredients. The reaction mixture was cooled to room temperature (20-30 °C) and the solvent was removed by evaporation at 40 °C under reduced pressure. To the residue, 20 mL of ethyl acetate was added for liquid-liquid separation. The organic phase was washed sequentially with 10 mL of water and 10 mL of saturated aqueous sodium chloride. The organic phase was dried with anhydrous sodium sulfate and concentrated to give 0.7 g of 4-bromo-3,5-dimethylbenzonitrile crude as a light yellow waxy solid. The crude was recrystallized by 1 mL of isopropanol to give an off-white solid. Yield: 0.5 g, yield: 73.5%.
References
[1] Patent: CN107417571, 2017, A. Location in patent: Paragraph 0058-0062; 0072-0076; 0094-0098
4-Bromo-3,5-dimethyl-benzonitrile Preparation Products And Raw materials
Raw materials
Preparation Products
4-Bromo-3,5-dimethyl-benzonitrile Suppliers
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- Country
- United Kingdom
- ProdList
- 6005
- Advantage
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- United Kingdom
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- vernam@fluorochem.co.uk
- Country
- United Kingdom
- ProdList
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View Lastest Price from 4-Bromo-3,5-dimethyl-benzonitrile manufacturers
- Product
- 4-bromo-3,5-dimethyl-benzonitrile 75344-77-3
- Price
- US $1400.00/Kg
- Min. Order
- 1Kg
- Purity
- 98
- Supply Ability
- 500 Kg
- Release date
- 2024-04-19
- Product
- 4-BROMO-3,5-DIMETHYL-BENZONITRILE 75344-77-3
- Price
- US $1.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 200kg
- Release date
- 2019-12-31