4-HYDROXY-3-METHOXY-2-NITROBENZALDEHYDE
- Product Name
- 4-HYDROXY-3-METHOXY-2-NITROBENZALDEHYDE
- CAS No.
- 2450-26-2
- Chemical Name
- 4-HYDROXY-3-METHOXY-2-NITROBENZALDEHYDE
- Synonyms
- NSC 95689;AKOS B028869;2-Nitrovanillin;Entacapone Impurity 28;Entacapone Impurity 67;LABOTEST-BB LT00159049;4-Hydroxy-2-Nitro-M-anisaldehyde;4-Hydroxy-3-methoxy-2-nitrobenzaL;4-HYDROXY-3-METHOXY-2-NITROBENZALDEHYDE;Benzaldehyde, 4-hydroxy-3-methoxy-2-nitro-
- CBNumber
- CB8744221
- Molecular Formula
- C8H7NO5
- Formula Weight
- 197.14
- MOL File
- Mol file
4-HYDROXY-3-METHOXY-2-NITROBENZALDEHYDE Property
- Melting point:
- 137-138 °C
- Boiling point:
- 387.8±42.0 °C(Predicted)
- Density
- 1.456±0.06 g/cm3(Predicted)
- storage temp.
- under inert gas (nitrogen or Argon) at 2-8°C
- form
- powder
- pka
- 7.40±0.25(Predicted)
- color
- Yellow
Safety
- HS Code
- 2913000090
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- H939925
- Product name
- 4-Hydroxy-3-methoxy-2-nitrobenzaldehyde
- Packaging
- 1g
- Price
- $130
- Updated
- 2021/12/16
- Product number
- OR55157
- Product name
- 4-Hydroxy-3-methoxy-2-nitrobenzaldehyde
- Packaging
- 5g
- Price
- $335
- Updated
- 2021/12/16
- Product number
- 4H54-1-HF
- Product name
- 4-Hydroxy-3-methoxy-2-nitrobenzaldehyde
- Packaging
- 5G
- Price
- $370
- Updated
- 2021/12/16
- Product number
- 114402
- Product name
- 4-Hydroxy-3-methoxy-2-nitrobenzaldehyde
- Purity
- 97%
- Packaging
- 1g
- Price
- $623
- Updated
- 2021/12/16
- Product number
- OR55157
- Product name
- 4-Hydroxy-3-methoxy-2-nitrobenzaldehyde
- Packaging
- 25g
- Price
- $1094
- Updated
- 2021/12/16
4-HYDROXY-3-METHOXY-2-NITROBENZALDEHYDE Chemical Properties,Usage,Production
Uses
4-hydroxy-3-methoxy-2-nitrobenzaldehyde is used in preparation of o-nitrolignin monomers as readily degradable lignin-generation agents for plants and degradation of lignin under UV irradiation.
Synthesis
2698-69-3
2450-26-2
Step 2: Preparation of 4-hydroxy-3-methoxy-2-nitrobenzaldehyde; A mixture of 4-formyl-2-methoxy-3-nitrophenyl acetate (438 g, 1.8 mol) and potassium carbonate (506 g, 3.7 mol) in methanol (4000 mL) was stirred for 16 hours at room temperature. Upon completion of the reaction, the reaction mixture was concentrated under reduced pressure to give a viscous oily substance. The oily substance was dissolved in water, acidified to pH<7 with 2N hydrochloric acid solution and subsequently extracted with ethyl acetate (EtOAc). The organic layer was washed with saturated brine, dried over anhydrous magnesium sulfate (MgSO4) and filtered. The filtrate was concentrated to 1/3 of the original volume under reduced pressure, a solid was precipitated, filtered and dried over air to afford the target product 4-hydroxy-3-methoxy-2-nitrobenzaldehyde (317 g, 88% yield). The product was characterized by 1H NMR (DMSO-d6): δ 9.69 (s, 1H), 7.68 (d, 1H), 7.19 (d, 1H), 3.82 (s, 3H).
References
[1] Journal of Heterocyclic Chemistry, 2015, vol. 52, # 5, p. 1406 - 1410
[2] Patent: WO2004/29055, 2004, A1. Location in patent: Page 51
[3] Journal of Chemical Research, Miniprint, 1990, # 12, p. 2831 - 2867
[4] Patent: WO2016/71380, 2016, A1. Location in patent: Page/Page column 43
[5] Patent: WO2008/70150, 2008, A1. Location in patent: Page/Page column 65-66
4-HYDROXY-3-METHOXY-2-NITROBENZALDEHYDE Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from 4-HYDROXY-3-METHOXY-2-NITROBENZALDEHYDE manufacturers
- Product
- 4-HYDROXY-3-METHOXY-2-NITROBENZALDEHYDE 2450-26-2
- Price
- US $1.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 200kg
- Release date
- 2020-01-09