3,4-Dichlorobenzonitrile
- Product Name
- 3,4-Dichlorobenzonitrile
- CAS No.
- 6574-99-8
- Chemical Name
- 3,4-Dichlorobenzonitrile
- Synonyms
- BUTTPARK 87\02-72;3,4-Dichlorobenzonit;3,4-Dichlorbenzonitril;3,4-Dichlorobenzonitrle;3,4-DICHLOROBENZONITRILE;Benzonitrile, 3,4-dichloro-;3,4-Dichlorobenzonitrile>3,4-Dichlorobenzonitrile 97%;Cyhalofop-butyl intermediate;3,4-Dichlorobenzonitrile ,99%
- CBNumber
- CB8753494
- Molecular Formula
- C7H3Cl2N
- Formula Weight
- 172.01
- MOL File
- 6574-99-8.mol
3,4-Dichlorobenzonitrile Property
- Melting point:
- 74-78 °C (lit.)
- Boiling point:
- 129-130 °C(Press: 0.01 Torr)
- Density
- 1.40±0.1 g/cm3(Predicted)
- storage temp.
- Sealed in dry,Room Temperature
- Water Solubility
- Insoluble in water
- form
- Powder or Crystalline Powder
- color
- White to brown
- BRN
- 2326352
- InChI
- InChI=1S/C7H3Cl2N/c8-6-2-1-5(4-10)3-7(6)9/h1-3H
- InChIKey
- KUWBYWUSERRVQP-UHFFFAOYSA-N
- SMILES
- C(#N)C1=CC=C(Cl)C(Cl)=C1
- LogP
- 2.8 at 21.5℃
- CAS DataBase Reference
- 6574-99-8(CAS DataBase Reference)
- NIST Chemistry Reference
- 3,4-Dichlorobenzonitrile(6574-99-8)
Safety
- Hazard Codes
- Xn,T,Xi
- Risk Statements
- 20/21/22-36/37/38
- Safety Statements
- 26-36
- RIDADR
- 3276
- WGK Germany
- 2
- Hazard Note
- Irritant/Toxic
- TSCA
- N
- HazardClass
- 6.1
- PackingGroup
- III
- HS Code
- 29269090
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- 532177
- Product name
- 3,4-Dichlorobenzonitrile
- Purity
- 97%
- Packaging
- 5g
- Price
- $38.57
- Updated
- 2025/07/31
- Product number
- D3415
- Product name
- 3,4-Dichlorobenzonitrile
- Purity
- >98.0%(GC)
- Packaging
- 5g
- Price
- $22
- Updated
- 2025/07/31
- Product number
- D3415
- Product name
- 3,4-Dichlorobenzonitrile
- Purity
- >98.0%(GC)
- Packaging
- 25g
- Price
- $59
- Updated
- 2025/07/31
- Product number
- D436533
- Product name
- 3,4-Dichlorobenzonitrile
- Packaging
- 500mg
- Price
- $65
- Updated
- 2021/12/16
- Product number
- D436533
- Product name
- 3,4-Dichlorobenzonitrile
- Packaging
- 100mg
- Price
- $45
- Updated
- 2021/12/16
3,4-Dichlorobenzonitrile Chemical Properties,Usage,Production
Chemical Properties
White solid
Uses
3,4-Dichlorobenzonitrilemay be used in the preparation of:
- 3,4-difluorobenzonitrile
- 3-chloro-4-fluorobenzonitrile
- 5-chloromethyl-3-( 3,4-dichlorophenyl)isoxazole
- N-[3-(2-pyridyl)isoquinolin-1-yl]-3,4-dichlorobenzamidine
General Description
3,4-Dichlorobenzonitrile (3,4-DCBN) is an aromatic nitrile that can be prepared from 3,4-dichlorobenzamide.
Flammability and Explosibility
Not classified
Synthesis
6287-38-3
6574-99-8
GENERAL STEPS: 3,4-Dichlorobenzaldehyde (1.0 mmol, 1.0 eq.) was dissolved in 4 mL of aqueous solution containing acetic acid (1.0 mmol, 1.0 eq.) in a 10 mL round-bottomed flask at 0°C. The reaction was carried out at 50°C with stirring for 6 hours or monitored by thin-layer chromatography (TLC) until the reaction was complete. The reaction mixture was stirred at 50 °C for 6 h or monitored by thin layer chromatography (TLC) until the reaction was complete. Upon completion of the reaction, the reaction was quenched with 10% aqueous NaHCO3 (1 mL) and subsequently extracted with ethyl acetate (3 x 10 mL). The organic phases were combined, dried with anhydrous Na2SO4, filtered and concentrated by rotary evaporator to give the crude product 3,4-dichlorobenzonitrile. The product was characterized directly unless further purification by automated silica gel fast chromatography was required to remove trace impurities (three embodiments).
Toxics Screening Level
The initial threshold screening level (ITSL) for 3,4-dichlorobenzonitrile is 2 μg/m3 based on an annual averaging time.
References
[1] Synthetic Communications, 2000, vol. 30, # 17, p. 3109 - 3114
[2] Journal of Chemical Research - Part S, 2001, # 5, p. 190 - 191
[3] Tetrahedron Letters, 2016, vol. 57, # 34, p. 3844 - 3847
[4] Bioorganic and Medicinal Chemistry, 2004, vol. 12, # 11, p. 2815 - 2824
[5] Synthetic Communications, 2002, vol. 32, # 23, p. 3621 - 3624
3,4-Dichlorobenzonitrile Preparation Products And Raw materials
Raw materials
Preparation Products
3,4-Dichlorobenzonitrile Suppliers
- Tel
- 800-4238616
- Fax
- +1-888-520-1075 / +1-503-283-1987
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- Americas
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View Lastest Price from 3,4-Dichlorobenzonitrile manufacturers
- Product
- 3,4-Dichlorobenzonitrile 6574-99-8
- Price
- US $60.00/KG
- Min. Order
- 1KG
- Purity
- 99.9%
- Supply Ability
- 100000kg
- Release date
- 2024-08-13
- Product
- 3,4-Dichlorobenzonitrile 6574-99-8
- Price
- US $15.00-10.00/KG
- Min. Order
- 1KG
- Purity
- 99%+ HPLC
- Supply Ability
- Monthly supply of 1 ton
- Release date
- 2021-07-10
- Product
- 3,4-Dichlorobenzonitrile 6574-99-8
- Price
- US $15.00-10.00/KG
- Min. Order
- 1KG
- Purity
- 99%+ HPLC
- Supply Ability
- Monthly supply of 1 ton
- Release date
- 2021-07-09