3-(2,2,3,3-TETRAFLUOROPROPOXY)-1,2-EPOXYPROPANE
- Product Name
- 3-(2,2,3,3-TETRAFLUOROPROPOXY)-1,2-EPOXYPROPANE
- CAS No.
- 19932-26-4
- Chemical Name
- 3-(2,2,3,3-TETRAFLUOROPROPOXY)-1,2-EPOXYPROPANE
- Synonyms
- DAIKIN E-5244;GLYCIDYL 2,2,3,3-TETRAFLUOROPROPYL ETHER;2-(4,4,5,5-TETRAFLUORO-2-OXAPENTYL)OXIRANE;3-(2,2,3,3-Tetrafluoropropoxy)-1,2-propene;[(2,2,3,3-tetrafluoropropoxy)methyl]oxirane;3-(2,2,2,3-TETRAFLUOROPROPOXY)-1,2-PROPENOXIDE;3-(2,2,3,3-TETRAFLUOROPROPOXY)-1,2-PROPENOXIDE;3-(2,2,3,3-TETRAFLUOROPROPOXY)-1,2-EPOXYPROPANE;[[(2,2,3,3-Tetrafluoropropyl)oxy]methyl]oxirane;Oxirane,2-[(2,2,3,3-tetrafluoropropoxy)Methyl]-
- CBNumber
- CB8764333
- Molecular Formula
- C6H8F4O2
- Formula Weight
- 188.12
- MOL File
- 19932-26-4.mol
3-(2,2,3,3-TETRAFLUOROPROPOXY)-1,2-EPOXYPROPANE Property
- Boiling point:
- 50 °C/4 mmHg (lit.)
- Density
- 1.327 g/mL at 25 °C (lit.)
- refractive index
- n20/D 1.366(lit.)
- Flash point:
- 175 °F
- form
- liquid
- color
- Clear, colourless
- InChI
- InChI=1S/C6H8F4O2/c7-5(8)6(9,10)3-11-1-4-2-12-4/h4-5H,1-3H2
- InChIKey
- DATKALAKXGFGPI-UHFFFAOYSA-N
- SMILES
- O1CC1COCC(F)(F)C(F)F
- CAS DataBase Reference
- 19932-26-4(CAS DataBase Reference)
- EPA Substance Registry System
- ((2,2,3,3-Tetrafluoropropoxy)methyl)oxirane (19932-26-4)
Safety
- Hazard Codes
- Xi,F,Xn
- Risk Statements
- 36/37/38-22
- Safety Statements
- 26-36/37/39
- RIDADR
- NA 1993 / PGIII
- WGK Germany
- 3
- Hazard Note
- Irritant
- TSCA
- TSCA listed
- HazardClass
- IRRITANT, FLAMMABLE
- HS Code
- 2932990090
- Storage Class
- 10 - Combustible liquids
- Hazard Classifications
- Acute Tox. 4 Oral
N-Bromosuccinimide Price
- Product number
- 474150
- Product name
- Glycidyl 2,2,3,3-tetrafluoropropyl ether
- Purity
- 97%
- Packaging
- 25ml
- Price
- $342
- Updated
- 2025/07/31
- Product number
- T310728
- Product name
- 3-(2,2,3,3-Tetrafluoropropoxy)-1,2-epoxypropane
- Packaging
- 100mg
- Price
- $60
- Updated
- 2021/12/16
- Product number
- 6711AD
- Product name
- 2-((2,2,3,3-Tetrafluoropropoxy)methyl)oxirane
- Packaging
- 1g
- Price
- $63
- Updated
- 2021/12/16
- Product number
- PC6867H
- Product name
- 3-(2,2,3,3-Tetrafluoropropoxy)-1,2-propenoxide
- Purity
- 97%
- Packaging
- 25g
- Price
- $65
- Updated
- 2021/12/16
- Product number
- 6711AD
- Product name
- 2-((2,2,3,3-Tetrafluoropropoxy)methyl)oxirane
- Packaging
- 5g
- Price
- $85
- Updated
- 2021/12/16
3-(2,2,3,3-TETRAFLUOROPROPOXY)-1,2-EPOXYPROPANE Chemical Properties,Usage,Production
Uses
Glycidyl 2,2,3,3-tetrafluoropropyl ether is used as pharmaceutical intermediate.
Synthesis
In a vessel with a separator, a dropping funnel and a stirring device, 200 g (2.16 mol) of 1,2-epichlorohydrin (1,2-epichlorohydrin:tetrafluoropropanol is 4.8:1) and 60 mL of cyclohexane were added, and stirred and heated at 350 raps/min until the cyclohexane refluxed. Then, 65 g of 40% aqueous potassium hydroxide and 60 g (0.45 mol) of tetrafluoropropanol were added dropwise to the reaction system, and the water was removed while the reaction was going on, and the reaction was completed when the aqueous potassium hydroxide and the tetrafluoropropanol were finished, and the reaction ended when there was no water out of the reaction. After cooling, filtering to remove potassium chloride, the mother liquor was heated to 65 ?? at atmospheric pressure to remove cyclohexane in the reaction solution, when cyclohexane was not distilled, the temperature was lowered to 30 ??, and then converted to reduced-pressure distillation, and pressure was adjusted so that the temperature of the distillation system was controlled at 65 ??, to recover the excess of 1,2-epichlorohydrin, and then, the fractions of 120-130 ??/250-300 Pa were collected, and the crude 3-(2,2,3,3) 3,3,3-tetrafluoropropoxy)-1,2-propene oxide was distilled under reduced pressure, and the fraction at 125-127 ??C/250-300 Pa was collected to obtain 70.5 g of 3-(2,2,3,3-tetrafluoropropoxy)-1,2-propene oxide, with a yield of 83.5% in terms of tetrafluoropropanol.
3-(2,2,3,3-TETRAFLUOROPROPOXY)-1,2-EPOXYPROPANE Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from 3-(2,2,3,3-TETRAFLUOROPROPOXY)-1,2-EPOXYPROPANE manufacturers
- Product
- 3-(2,2,3,3-tetrafluoropropoxy)-1,2-epoxypropane 19932-26-4
- Price
- US $2.20-8.80/kg
- Min. Order
- 1kg
- Purity
- 99%
- Supply Ability
- 100kg
- Release date
- 2025-06-24
- Product
- 3-(2,2,3,3-TETRAFLUOROPROPOXY)-1,2-EPOXYPROPANE 19932-26-4
- Price
- US $0.00-0.00/KG
- Min. Order
- 1KG
- Purity
- 98%
- Supply Ability
- 1Ton
- Release date
- 2022-10-08
- Product
- 5-FLUORO-6-METHOXY-PYRIDIN-3-YLAMINE3-(2,2,3,3-TETRAFLUOROPROPOXY)-1,2-EPOXYPROPANE 19932-26-4
- Price
- US $1.00/KG
- Min. Order
- 1KG
- Purity
- 98%-99.9%
- Supply Ability
- 200kg
- Release date
- 2020-01-12