TETRAHYDROCORTISOL Property

Melting point:

−108 °C(lit.)

Boiling point:

65-67 °C(lit.)

Density 

0.889 g/mL at 25 °C(lit.)

vapor density 

2.5 (vs air)

vapor pressure 

114 mm Hg ( 15 °C)

refractive index 

n20/D 1.407(lit.)

Flash point:

1 °F

storage temp. 

2-8°C

solubility 

Chloroform (Very Slightly, Heated, Sonicated), DMSO (Slightly), Methanol (Slightly)

form 

Solid

pka

12.48±0.70(Predicted)

color 

<10(APHA)

Stability:

Hygroscopic

Safety

Hazard Codes 

Xi,Xn

Risk Statements 

36/37-40

Safety Statements 

26-36-36/37

RIDADR 

UN 2056 3/PG 2

WGK Germany 

1

RTECS 

LU5950000

F 

3-10-23

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Danger

Hazard statements

H225Highly Flammable liquid and vapour

H370Causes damage to organs

Precautionary statements

P210Keep away from heat/sparks/open flames/hot surfaces. — No smoking.

P280Wear protective gloves/protective clothing/eye protection/face protection.

TETRAHYDROCORTISOL Chemical Properties,Usage,Production

Uses

Tetrahydrocortisol is excreted in large amounts in premenopausal patients with early breast cancer. Tetrahydrocortisol has been found to be produced by lymphocytes in both normal and cancer bearing patients however, the concentration of Tetrahydrocortisol has increased in patients with cancer.

Definition

ChEBI: Tetrahydrocortisol is a 3alpha-hydroxy steroid, an 11beta-hydroxy steroid, a 17alpha-hydroxy steroid, a 21-hydroxy steroid, a 20-oxo steroid, a glucocorticoid, a primary alpha-hydroxy ketone and a tertiary alpha-hydroxy ketone. It derives from a hydride of a 5beta-pregnane.