2-DIMETHYLAMINO-4,5,6,7-TETRABROMO-1H-BENZIMIDAZOLE
- Product Name
- 2-DIMETHYLAMINO-4,5,6,7-TETRABROMO-1H-BENZIMIDAZOLE
- Chemical Name
- 2-DIMETHYLAMINO-4,5,6,7-TETRABROMO-1H-BENZIMIDAZOLE
- Synonyms
- DMAT;CK2 INHIBITOR II;CASEIN KINASE II INHIBITOR II;2-DIMETHYLAMINO-4,5,6,7-TETRABROMO-1H-BENZIMIDAZOLE
- CBNumber
- CB8797429
- Molecular Formula
- C9H7Br4N3
- Formula Weight
- 476.78798
- MOL File
- Mol file
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2-DIMETHYLAMINO-4,5,6,7-TETRABROMO-1H-BENZIMIDAZOLE Chemical Properties,Usage,Production
Biological Activity
High affinity, cell-permeable inhibitor of casein kinase 2 (CK2) (K i = 40 nM; IC 50 = 0.13 μ M). Displays no activity at CK1 at concentrations up to 200 μ M. Also inhibits Pim kinase (IC 50 values are 0.097, 0.148 and 1.6 μ M for Pim-3, Pim-1 and Pim-2 kinase respectively), and protein kinase D1 (IC 50 = 0.18 μ M). Derivative of TBB (4,5,6,7-Tetrabromobenzotriazole).
2-DIMETHYLAMINO-4,5,6,7-TETRABROMO-1H-BENZIMIDAZOLE Preparation Products And Raw materials
Raw materials
Preparation Products
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