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5-BROMO-2-METHOXY-ISONICOTINIC ACID METHYL ESTER

Product Name
5-BROMO-2-METHOXY-ISONICOTINIC ACID METHYL ESTER
CAS No.
886365-25-9
Chemical Name
5-BROMO-2-METHOXY-ISONICOTINIC ACID METHYL ESTER
Synonyms
Methyl 5-bromo-2-methoxyisonicotinate;Methyl 2-methoxy-5-bromopyridine-4-carboxylate;Methyl 5-bromo-2-methoxypyridine-4-carboxylate;5-BROMO-2-METHOXY-ISONICOTINIC ACID METHYL ESTER;4-Pyridinecarboxylic acid, 5-bromo-2-methoxy-, methyl ester
CBNumber
CB8802815
Molecular Formula
C8H8BrNO3
Formula Weight
246.06
MOL File
Mol file
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5-BROMO-2-METHOXY-ISONICOTINIC ACID METHYL ESTER Property

Boiling point:
276.4±35.0 °C(Predicted)
Density 
1.530±0.06 g/cm3(Predicted)
storage temp. 
Sealed in dry,Room Temperature
pka
-1.09±0.18(Predicted)
Appearance
White to light yellow Solid
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Safety

HS Code 
2933399990
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Precautionary statements

P260Do not breathe dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P312Call a POISON CENTER or doctor/physician if you feel unwell.

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N-Bromosuccinimide Price

Matrix Scientific
Product number
101380
Product name
Methyl 5-bromo-2-methoxypyridine-4-carboxylate
Purity
>97%
Packaging
500mg
Price
$258
Updated
2021/12/16
SynQuest Laboratories
Product number
4H58-9-63
Product name
Methyl 5-bromo-2-methoxyisonicotinate
Packaging
1g
Price
$384
Updated
2021/12/16
Matrix Scientific
Product number
101380
Product name
Methyl 5-bromo-2-methoxypyridine-4-carboxylate
Purity
>97%
Packaging
1g
Price
$418
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
HCH0354021
Product name
5-BROMO-2-METHOXY-ISONICOTINIC ACID METHYL ESTER
Purity
95.00%
Packaging
5MG
Price
$505.51
Updated
2021/12/16
Ambeed
Product number
A163937
Product name
Methyl5-bromo-2-methoxyisonicotinate
Purity
97%
Packaging
100mg
Price
$53
Updated
2021/12/16
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5-BROMO-2-METHOXY-ISONICOTINIC ACID METHYL ESTER Chemical Properties,Usage,Production

Synthesis

67-56-1

936011-17-5

886365-25-9

To a methanolic (100 mL) solution of 5-bromo-2-methoxypyridine-4-carbaldehyde (23.5 g, 108.8 mmol) was sequentially added a methanolic (75 mL) solution of iodine (35.9 mg, 141.4 mmol). A methanol (75 mL) solution of potassium hydroxide (15.9 g, 282.8 mmol) was added at 0 °C. The reaction mixture was stirred at 0 °C for 1 h. The reaction was subsequently quenched with saturated aqueous sodium bisulfite solution. The reaction mixture was diluted with dichloromethane (400 mL). The organic phase was separated, washed sequentially with water (150 mL) and brine (150 mL), dried over anhydrous sodium sulfate and concentrated in vacuum. The residue was purified by fast column chromatography (eluent: petroleum ether/ethyl acetate = 20:1, v/v) to afford methyl 5-bromo-2-methoxypyridine-4-carboxylate (14.9 g) as a light yellow solid.

References

[1] Patent: WO2018/83136, 2018, A1. Location in patent: Page/Page column 38

5-BROMO-2-METHOXY-ISONICOTINIC ACID METHYL ESTER Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from 5-BROMO-2-METHOXY-ISONICOTINIC ACID METHYL ESTER manufacturers

Career Henan Chemical Co
Product
5-BROMO-2-METHOXY-ISONICOTINIC ACID METHYL ESTER 886365-25-9
Price
US $1.00/g
Min. Order
1g
Purity
98%
Supply Ability
100KG
Release date
2020-01-12

886365-25-9, 5-BROMO-2-METHOXY-ISONICOTINIC ACID METHYL ESTERRelated Search:


  • 5-BROMO-2-METHOXY-ISONICOTINIC ACID METHYL ESTER
  • Methyl 5-bromo-2-methoxypyridine-4-carboxylate
  • Methyl 5-bromo-2-methoxyisonicotinate
  • Methyl 2-methoxy-5-bromopyridine-4-carboxylate
  • 4-Pyridinecarboxylic acid, 5-bromo-2-methoxy-, methyl ester
  • 886365-25-9