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GSK-3484862

Product Name
GSK-3484862
CAS No.
2170136-65-7
Chemical Name
GSK-3484862
Synonyms
GSK-3484862;GSK-3484862 (GSKMI-714);GSK-3484862, 10 mM in DMSO;Benzeneacetamide, α-[[3,5-dicyano-6-(dimethylamino)-4-ethyl-2-pyridinyl]thio]-, (αR)-;inhibit,methyltransferase1,5-Azacytidine,Inhibitor,hypomethylation,Dnmt1,therapies,GSK3484862,DNA MTases,DNA,GSK-3484862,epigenetic,DNA Methyltransferase,DNMTs,GSK 3484862
CBNumber
CB88054418
Molecular Formula
C19H19N5OS
Formula Weight
365.45
MOL File
2170136-65-7.mol
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GSK-3484862 Property

Boiling point:
620.5±55.0 °C(Predicted)
Density 
1.30±0.1 g/cm3(Predicted)
solubility 
DMSO:20.83(Max Conc. mg/mL);57.0(Max Conc. mM)
pka
14.62±0.50(Predicted)
form 
Solid
color 
Light yellow to yellow
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

ChemScene
Product number
CS-0109599
Product name
GSK-3484862
Purity
99.94%
Packaging
10mg
Price
$250
Updated
2021/12/16
ChemScene
Product number
CS-0109599
Product name
GSK-3484862
Purity
99.94%
Packaging
50mg
Price
$650
Updated
2021/12/16
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GSK-3484862 Chemical Properties,Usage,Production

Description

GSK-3484862 is a non-covalent inhibitor for Dnmt1. GSK-3484862 induces DNA hypomethylation to against cancer.

in vitro

In total, methylation mapping supports the conclusion that GSK-3484862 treatment produces a drop in DNA methylation consistent with selective and near complete inhibition of DNMT1._x000D_ _x000D_ Reference: Epigenetics Chromatin. 2021 Dec 15;14(1):56. https://pubmed.ncbi.nlm.nih.gov/34906184/

target

GSK-3484862 is a non-covalent inhibitor for DNA methyltransferase (Dnmt1). GSK-3484862 induces DNA hypomethylation to against cancer.

GSK-3484862 Preparation Products And Raw materials

Raw materials

Preparation Products

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GSK-3484862 Suppliers

Chengdu PEIP Pharmaceutical Technology Co., LTD.
Tel
028-61715638 18011352545
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QQ:1242335375
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1242335275@qq.com
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China
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369
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Shanghai EFE Biological Technology Co., Ltd.
Tel
021-65675885 18964387627
Fax
021-65675885
Email
info@efebio.com
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China
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9804
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58
Shanghai TuZhi Chemical Co., Ltd.
Tel
19542790274 19542790274
Fax
QQ1456295541
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2119559397@qq.com
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China
ProdList
845
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50
Shanghai SuperLan Chemcial Technique Centre
Tel
021-2022843681 15618226720
Fax
+86-21-51601218
Email
lucy@atkchemical.com
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China
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9987
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Chuzhou KeMail Chemical Technology Co., Ltd
Tel
0550-5196001 15000891977
Fax
0550-5196001
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wj520wjxby@126.com
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China
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Chengdu Peter-like Biotechnology Co., Ltd.
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028-81700200 18108052721
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China
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ChemeGen(Shanghai) Biotechnology Co.,Ltd.
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18818260767
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QQ 3610331285
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sales@chemegen.com
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InvivoChem
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13549236410
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sales@invivochem.cn
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China
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Beijing Biocreative Technology Co., Ltd.
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15522676233
Email
3007606172@qq.com
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China
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TargetMol Chemicals Inc.
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4008200310
Email
marketing@tsbiochem.com
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China
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Nantong QuanYi Biotechnology Co., Ltd
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0513-66337626 18051384581
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sales@chemhifuture.com
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China
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Shanghai?Medlife?Pharm-Tech?Co.,?Ltd
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021-59167510 18117107507
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Nanjing Shizhou Biology Technology Co.,Ltd
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025-85560043 15850508050
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025-85563444
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RD International Technology Co., Limited
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Jiangsu Aikon Biopharmaceutical R&D Co.,Ltd
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Email
sangon@qq.com
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CHINA
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Neobioscience Co., Ltd.
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info@neobioscience.com
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CHINA
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6681
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Absin Bioscience Inc.
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chenjw@absin.cn
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CHINA
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Proteintech China
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Proteintech-CN@ptglab.com
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2170136-65-7, GSK-3484862Related Search:


  • GSK-3484862
  • inhibit,methyltransferase1,5-Azacytidine,Inhibitor,hypomethylation,Dnmt1,therapies,GSK3484862,DNA MTases,DNA,GSK-3484862,epigenetic,DNA Methyltransferase,DNMTs,GSK 3484862
  • Benzeneacetamide, α-[[3,5-dicyano-6-(dimethylamino)-4-ethyl-2-pyridinyl]thio]-, (αR)-
  • GSK-3484862 (GSKMI-714)
  • GSK-3484862, 10 mM in DMSO
  • 2170136-65-7