ChemicalBook > CAS DataBase List > Boc-C1-PEG3-C4-OH
Boc-C1-PEG3-C4-OH
- Product Name
- Boc-C1-PEG3-C4-OH
- CAS No.
- 2376724-97-7
- Chemical Name
- Boc-C1-PEG3-C4-OH
- Synonyms
- Boc-C1-PEG3-C4-OH;Acetic acid, 2-[2-[2-[(6-hydroxyhexyl)oxy]ethoxy]ethoxy]-, 1,1-dimethylethyl ester
- CBNumber
- CB88054685
- Molecular Formula
- C16H32O6
- Formula Weight
- 320.42
- MOL File
- 2376724-97-7.mol
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Boc-C1-PEG3-C4-OH Property
- Boiling point:
- 409.3±35.0 °C(Predicted)
- Density
- 1.024±0.06 g/cm3(Predicted)
- solubility
- Soluble in DMSO
- form
- Liquid
- pka
- 15.18±0.10(Predicted)
- color
- Colorless to light yellow
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Boc-C1-PEG3-C4-OH Chemical Properties,Usage,Production
Biological Activity
Boc-C1-PEG3-C4-OH is a PROTAC linker, which refers to the Alkyl/ether composition. Boc-C1-PEG3-C4-OH can be used in the synthesis of a series of PROTACs. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References
[1]. Tovell H, et al. Design and Characterization of SGK3-PROTAC1, an Isoform Specific SGK3 Kinase PROTAC Degrader. ACS Chem Biol. 2019 Sep 20;14(9):2024-2034.
Boc-C1-PEG3-C4-OH Preparation Products And Raw materials
Raw materials
Preparation Products
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