Hepcidin-20 (human)

Product Name: Hepcidin-20 (human)
CAS No.: 342790-23-2
Chemical Name: Hepcidin-20 (human)
Synonyms: Hepcidin-20 (human);L-Threonine, L-isoleucyl-L-cysteinyl-L-isoleucyl-L-phenylalanyl-L-cysteinyl-L-cysteinylglycyl-L-cysteinyl-L-cysteinyl-L-histidyl-L-arginyl-L-seryl-L-lysyl-L-cysteinylglycyl-L-methionyl-L-cysteinyl-L-cysteinyl-L-lysyl-, cyclic (2→8),(5→18),(6→17),(9→14)-tetrakis(disulfide)
CBNumber: CB88055394
Molecular Formula: C85H135N27O23S9
Formula Weight: 2191.75
MOL File: 342790-23-2.mol

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Hepcidin-20 (human) Property

Density: 1.60±0.1 g/cm3(Predicted)
pka: 3.21±0.10(Predicted)
Sequence: H-Ile-Cys-Ile-Phe-Cys-Cys-Gly-Cys-Cys-His-Arg-Ser-Lys-Cys-Gly-Met-Cys-Cys-Lys-Thr-OH(Disulfide bonds, air oxidized)

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Hazard and Precautionary Statements (GHS)

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Hepcidin-20 (human) Chemical Properties,Usage,Production

Uses

Hepcidin-20 (human) is a histidine-containing, cysteine-rich, β-sheet structured peptide. Hepcidin-20 (human) shows antifungal activity. Hepcidin-20 (human) inhibits biofilm formation and bacterial cell metabolism of polysaccharide intercellular adhesin (PIA)-positive and PIA-negative strains[1][2][3].

References

[1] Maisetta G, et al. pH-dependent disruption of Escherichia coli ATCC 25922 and model membranes by the human antimicrobial peptides hepcidin 20 and 25. FEBS J. 2013 Jun;280(12):2842-54. DOI:10.1111/febs.12288
[2] Del Gaudio G, et al. Antifungal Activity of the Noncytotoxic Human Peptide Hepcidin 20 against Fluconazole-Resistant Candida glabrata in Human Vaginal Fluid. Antimicrob Agents Chemother. 2013 Sep;57(9):4314-4321. DOI:10.1128/AAC.00904-13
[3] Brancatisano FL, et al. Inhibitory effect of the human liver-derived antimicrobial peptide hepcidin 20 on biofilms of polysaccharide intercellular adhesin (PIA)-positive and PIA-negative strains of Staphylococcus epidermidis. Biofouling. 2014;30(4):435-46. DOI:10.1080/08927014.2014.888062

Hepcidin-20 (human) Preparation Products And Raw materials

Raw materials

Preparation Products

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Hepcidin-20 (human) Suppliers

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342790-23-2, Hepcidin-20 (human)Related Search:

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Hepcidin-20 (human)

L-Threonine, L-isoleucyl-L-cysteinyl-L-isoleucyl-L-phenylalanyl-L-cysteinyl-L-cysteinylglycyl-L-cysteinyl-L-cysteinyl-L-histidyl-L-arginyl-L-seryl-L-lysyl-L-cysteinylglycyl-L-methionyl-L-cysteinyl-L-cysteinyl-L-lysyl-, cyclic (2→8),(5→18),(6→17),(9→14)-tetrakis(disulfide)

342790-23-2