3,10-Dioxa-5,8-diazaundecanoic acid, 11-(9H-fluoren-9-yl)-6,9-dioxo-

Product Name: 3,10-Dioxa-5,8-diazaundecanoic acid, 11-(9H-fluoren-9-yl)-6,9-dioxo-
CAS No.: 1599440-08-0
Chemical Name: 3,10-Dioxa-5,8-diazaundecanoic acid, 11-(9H-fluoren-9-yl)-6,9-dioxo-
Synonyms: 1-(9H-Fluoren-9-yl)-3,6-dioxo-2,9-dioxa-4,7-diazaundecan-11-oic acid;Fmoc-Gly-AMOA-OH;Fmoc-Gly-NH-CH2-O-CH2COOH;N-(Fmoc-glycyl)-2-(aminomethoxy)acetic acid;2-[[2-(Fmoc-amino)acetamido]methoxy]acetic Acid;2-((2-(Fmoc-amino)acetylamino)methoxy)acetic acid;1- (9H fluoren-9 yl) -3,6-dioxo-2,9-dioxa-4,7-diaza-decane-11 acid;11-(9H-Fluoren-9-yl)-6,9-dioxo-3,10-dioxa-5,8-diazaundecanoic acid;3,10-Dioxa-5,8-diazaundecanoic acid, 11-(9H-fluoren-9-yl)-6,9-dioxo-;2-[[[2-(9H-fluoren-9-ylmethoxycarbonylamino)acetyl]amino]methoxy]acetic acid
CBNumber: CB88105611
Molecular Formula: C20H20N2O6
Formula Weight: 384.38
MOL File: 1599440-08-0.mol

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3,10-Dioxa-5,8-diazaundecanoic acid, 11-(9H-fluoren-9-yl)-6,9-dioxo- Property

Boiling point:: 721.6±55.0 °C(Predicted)
Density: 1.336±0.06 g/cm3(Predicted)
pka: 3.21±0.10(Predicted)
form: Solid
color: White to off-white
InChI: InChI=1S/C20H20N2O6/c23-18(22-12-27-11-19(24)25)9-21-20(26)28-10-17-15-7-3-1-5-13(15)14-6-2-4-8-16(14)17/h1-8,17H,9-12H2,(H,21,26)(H,22,23)(H,24,25)
InChIKey: LIBCNUNKCWYZAX-UHFFFAOYSA-N
SMILES: C(O)(=O)COCNC(=O)CNC(=O)OCC1C2=C(C=CC=C2)C2=C1C=CC=C2

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P337+P313IF eye irritation persists: Get medical advice/attention.

P501Dispose of contents/container to..…

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3,10-Dioxa-5,8-diazaundecanoic acid, 11-(9H-fluoren-9-yl)-6,9-dioxo- Chemical Properties,Usage,Production

Uses

Fmoc-Gly-NH-CH2-O-CH2COOH is an ADC linker. Fmoc-Gly-NH-CH2-O-CH2COOH can be used for synthesis of ADCs[1].

References

[1] Tsuda Toshifumi, et al. Novel cyclic dinucleotide derivative and its antibody-drug conjugate having STING agonist activity. Patent. WO2020050406.

3,10-Dioxa-5,8-diazaundecanoic acid, 11-(9H-fluoren-9-yl)-6,9-dioxo- Preparation Products And Raw materials

Raw materials

Preparation Products

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3,10-Dioxa-5,8-diazaundecanoic acid, 11-(9H-fluoren-9-yl)-6,9-dioxo- Suppliers

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1599440-08-0, 3,10-Dioxa-5,8-diazaundecanoic acid, 11-(9H-fluoren-9-yl)-6,9-dioxo-Related Search:

3,10-Dioxa-5,8-diazaundecanoic acid, 11-(9H-fluoren-9-yl)-6,9-dioxo-

1-(9H-Fluoren-9-yl)-3,6-dioxo-2,9-dioxa-4,7-diazaundecan-11-oic acid

11-(9H-Fluoren-9-yl)-6,9-dioxo-3,10-dioxa-5,8-diazaundecanoic acid

Fmoc-Gly-AMOA-OH

Fmoc-Gly-NH-CH2-O-CH2COOH

N-(Fmoc-glycyl)-2-(aminomethoxy)acetic acid

2-[[[2-(9H-fluoren-9-ylmethoxycarbonylamino)acetyl]amino]methoxy]acetic acid

1- (9H fluoren-9 yl) -3,6-dioxo-2,9-dioxa-4,7-diaza-decane-11 acid

2-[(2-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)acetamido)methoxy]acetic acid

2-[[2-(Fmoc-amino)acetamido]methoxy]acetic Acid

2-((2-(Fmoc-amino)acetylamino)methoxy)acetic acid

1599440-08-0

ADC