ChemicalBook > CAS DataBase List > 1,6-Naphthyridine-6(5H)-carboxamide, N-[2-(4-fluorophenoxy)-5-pyrimidinyl]-5-(4-fluorophenyl)-7,8-dihydro-, (5S)-
1,6-Naphthyridine-6(5H)-carboxamide, N-[2-(4-fluorophenoxy)-5-pyrimidinyl]-5-(4-fluorophenyl)-7,8-dihydro-, (5S)-
- Product Name
- 1,6-Naphthyridine-6(5H)-carboxamide, N-[2-(4-fluorophenoxy)-5-pyrimidinyl]-5-(4-fluorophenyl)-7,8-dihydro-, (5S)-
- CAS No.
- 2471967-92-5
- Chemical Name
- 1,6-Naphthyridine-6(5H)-carboxamide, N-[2-(4-fluorophenoxy)-5-pyrimidinyl]-5-(4-fluorophenyl)-7,8-dihydro-, (5S)-
- Synonyms
- BAY-899;(5S)-N-[2-(4-fluorophenoxy)pyrimidin-5-yl]-5-(4-fluorophenyl)-5,6,7,8-tetrahydro-1,6-naphthyridine-6-carboxamide;1,6-Naphthyridine-6(5H)-carboxamide, N-[2-(4-fluorophenoxy)-5-pyrimidinyl]-5-(4-fluorophenyl)-7,8-dihydro-, (5S)-
- CBNumber
- CB88186364
- Molecular Formula
- C25H19F2N5O2
- Formula Weight
- 459.45
- MOL File
- 2471967-92-5.mol
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1,6-Naphthyridine-6(5H)-carboxamide, N-[2-(4-fluorophenoxy)-5-pyrimidinyl]-5-(4-fluorophenyl)-7,8-dihydro-, (5S)- Property
- Density
- 1.397±0.06 g/cm3(Predicted)
- storage temp.
- Store at -20°C
- solubility
- DMSO: 1mg/mL, clear
- form
- Solid
- pka
- 12.52±0.40(Predicted)
- color
- White to off-white
- optical activity
- [α]/D 165 to 195°, c =1 in chloroform-d
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N-Bromosuccinimide Price
Sigma-Aldrich
- Product number
- SML2890
- Product name
- BAY-899
- Purity
- ≥98% (HPLC)
- Packaging
- 5MG
- Price
- $117
- Updated
- 2024/03/01
Sigma-Aldrich
- Product number
- SML2890
- Product name
- BAY-899
- Purity
- ≥98% (HPLC)
- Packaging
- 25MG
- Price
- $468
- Updated
- 2024/03/01
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1,6-Naphthyridine-6(5H)-carboxamide, N-[2-(4-fluorophenoxy)-5-pyrimidinyl]-5-(4-fluorophenyl)-7,8-dihydro-, (5S)- Chemical Properties,Usage,Production
Biological Activity
BAY-899 is an orally available, potent and selective antagonist of the human luteinizing hormone receptor (hLH-R) th at reduces sex hormone levels in several animal models. BAY-899 likely binds to a putative rhodopsin-like binding cavity located within the 7-transmembrane region of the hLH-receptor.
1,6-Naphthyridine-6(5H)-carboxamide, N-[2-(4-fluorophenoxy)-5-pyrimidinyl]-5-(4-fluorophenyl)-7,8-dihydro-, (5S)- Preparation Products And Raw materials
Raw materials
Preparation Products
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1,6-Naphthyridine-6(5H)-carboxamide, N-[2-(4-fluorophenoxy)-5-pyrimidinyl]-5-(4-fluorophenyl)-7,8-dihydro-, (5S)- Suppliers
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