SR 3677 dihydrochloride

Product Name: SR 3677 dihydrochloride
CAS No.: 1781628-88-3
Chemical Name: SR 3677 dihydrochloride
CBNumber: CB88202846
Molecular Formula: C22H25ClN4O4
Formula Weight: 444.92
MOL File: 1781628-88-3.mol

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SR 3677 dihydrochloride Property

storage temp.: Store at -20°C
solubility: Soluble in DMSO

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Hazard and Precautionary Statements (GHS)

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SR 3677 dihydrochloride Chemical Properties,Usage,Production

Uses

SR-3677 dihydrochloride (compound 5) is a potent and selective ROCK-I and ROCK-II inhibitor with an IC50 values of 56 nM and 3 nM[1].

IC 50

ROCK-I: 56 nM (IC₅₀); ROCK-II: 3 nM (IC₅₀)

storage

Desiccate at RT

References

[1] Feng Y, et al. Discovery of substituted 4-(pyrazol-4-yl)-phenylbenzodioxane-2-carboxamides as potent and highly selective Rho kinase (ROCK-II) inhibitors. J Med Chem. 2008 Nov 13;51(21):6642-5. DOI:10.1021/jm800986w

SR 3677 dihydrochloride Preparation Products And Raw materials

Raw materials

Preparation Products

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SR 3677 dihydrochloride Suppliers

China 7 United States 1 Global 8

TargetMol Chemicals Inc.

Tel: +1-781-999-5354; +17819995354
Email: marketing@targetmol.com
Country: United States
ProdList: 32435
Advantage: 58

1781628-88-3, SR 3677 dihydrochlorideRelated Search:

SR-95531 N-[2-[2-(Dimethylamino)ethoxy]-4-(1H-pyrazol-4-yl)phenyl]-2,3-dihydro-1,4-benzodioxin-2-carboxamide

1781628-88-3