ChemicalBook > CAS DataBase List > Glycinamide, glycylglycyl-L-phenylalanyl-N-[(carboxymethoxy)methyl]-
Glycinamide, glycylglycyl-L-phenylalanyl-N-[(carboxymethoxy)methyl]-
- Product Name
- Glycinamide, glycylglycyl-L-phenylalanyl-N-[(carboxymethoxy)methyl]-
- CAS No.
- 1599440-20-6
- Chemical Name
- Glycinamide, glycylglycyl-L-phenylalanyl-N-[(carboxymethoxy)methyl]-
- Synonyms
- GGFG-Acid;H-GGFG-Glycolic acid;Gly-Gly-Phe-Gly-NH-CH2-O-CH2COOH;Gly-Gly-L-Phe-N-[(carboxymethoxy)methyl]Glycinamide;Glycinamide, glycylglycyl-L-phenylalanyl-N-[(carboxymethoxy)methyl]-;(S)-16-amino-10-benzyl-6,9,12,15-tetraoxo-3-oxa-5,8,11,14-tetraazahexadecanoic acid;(S)-16-amino-10-benzyl-6,9,12,15-tetraoxo-3-oxa-5,8,11,14-tetraazahexadecan-1-oic acid;(S)-13-Amino-5-(2-amino-2-oxoethyl)-7-benzyl-6,9,12-trioxo-3-oxa-5,8,11-triaza-1-tridecanoic Acid
- CBNumber
- CB88218654
- Molecular Formula
- C18H25N5O7
- Formula Weight
- 423.42
- MOL File
- 1599440-20-6.mol
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Glycinamide, glycylglycyl-L-phenylalanyl-N-[(carboxymethoxy)methyl]- Property
- Boiling point:
- 971.9±65.0 °C(Predicted)
- Density
- 1.339±0.06 g/cm3(Predicted)
- pka
- 3.20±0.10(Predicted)
- form
- Solid
- color
- White to off-white
- InChIKey
- XGFHCMGJKUDBRZ-ZDUSSCGKSA-N
- SMILES
- C(N)(=O)CN(C(=O)[C@H](CC1=CC=CC=C1)NC(=O)CNC(=O)CN)COCC(O)=O
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Glycinamide, glycylglycyl-L-phenylalanyl-N-[(carboxymethoxy)methyl]- Chemical Properties,Usage,Production
Uses
Gly-Gly-Phe-Gly-NH-CH2-O-CH2COOH is an ADC Linker that can be used to synthesize Drug-Linker Conjugates for ADC. Especially for the synthesis of Deruxtecan (HY-13631E), a toxic drug-linker conjugate[1].
References
[1] Masuda,et al. Preparation of antibody-drug conjugates for cancer therapy. World Intellectual Property Organization, WO2014057687 A1. 2014-04-17.
Glycinamide, glycylglycyl-L-phenylalanyl-N-[(carboxymethoxy)methyl]- Preparation Products And Raw materials
Raw materials
Preparation Products
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Glycinamide, glycylglycyl-L-phenylalanyl-N-[(carboxymethoxy)methyl]- Suppliers
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View Lastest Price from Glycinamide, glycylglycyl-L-phenylalanyl-N-[(carboxymethoxy)methyl]- manufacturers
Huida Pharmaceutical Technology (Shanghai) Co., Ltd.
- Product
- Glycinamide, glycylglycyl-L-phenylalanyl-N-[(carboxymethoxy)methyl]- 1599440-20-6
- Price
- US $0.00-0.00/kg
- Min. Order
- 0.1kg
- Purity
- 98%
- Supply Ability
- 1000kg
- Release date
- 2023-02-28