3-METHYLPYRAZINE-2-CARBOXYLIC ACID METHYL ESTER
- Product Name
- 3-METHYLPYRAZINE-2-CARBOXYLIC ACID METHYL ESTER
- CAS No.
- 41110-29-6
- Chemical Name
- 3-METHYLPYRAZINE-2-CARBOXYLIC ACID METHYL ESTER
- Synonyms
- Methyl 3-Methyl-2-pyrazinecarboxylate;METHYL 3-METHYLPYRAZINE-2-CARBOXYLATE;3-METHYLPYRAZINE-2-CARBOXYLIC ACID METHYL ESTER;2-Pyrazinecarboxylic acid, 3-methyl-, methyl ester;Pyrazinecarboxylic acid, 3-methyl-, methyl ester (9CI)
- CBNumber
- CB8831266
- Molecular Formula
- C7H8N2O2
- Formula Weight
- 152.15
- MOL File
- 41110-29-6.mol
3-METHYLPYRAZINE-2-CARBOXYLIC ACID METHYL ESTER Property
- Boiling point:
- 221.8±35.0 °C(Predicted)
- Density
- 1.169±0.06 g/cm3(Predicted)
- storage temp.
- 2-8°C
- pka
- -0?+-.0.10(Predicted)
- Appearance
- White to yellow Solid
- InChI
- InChI=1S/C7H8N2O2/c1-5-6(7(10)11-2)9-4-3-8-5/h3-4H,1-2H3
- InChIKey
- AUDOINDPGADJPY-UHFFFAOYSA-N
- SMILES
- C1(C(OC)=O)=NC=CN=C1C
Safety
- HS Code
- 2933998090
N-Bromosuccinimide Price
- Product number
- M219760
- Product name
- Methyl3-Methylpyrazine-2-carboxylate
- Packaging
- 100mg
- Price
- $60
- Updated
- 2021/12/16
- Product number
- Z4722
- Product name
- Methyl3-methylpyrazine-2-carboxylate
- Packaging
- 250mg
- Price
- $72
- Updated
- 2021/12/16
- Product number
- OR927273
- Product name
- Methyl3-methylpyrazine-2-carboxylate
- Purity
- 96%
- Packaging
- 250mg
- Price
- $115
- Updated
- 2021/12/16
- Product number
- OR927273
- Product name
- Methyl3-methylpyrazine-2-carboxylate
- Purity
- 96%
- Packaging
- 1g
- Price
- $190
- Updated
- 2021/12/16
- Product number
- OR927273
- Product name
- Methyl3-methylpyrazine-2-carboxylate
- Purity
- 96%
- Packaging
- 5g
- Price
- $410
- Updated
- 2021/12/16
3-METHYLPYRAZINE-2-CARBOXYLIC ACID METHYL ESTER Chemical Properties,Usage,Production
Synthesis
67-56-1
41110-28-5
41110-29-6
3-Methylpyrazine-2-carboxylic acid (19.95 g, 144 mmol) was suspended in methanol (500 mL) in a 2L round bottom flask. The suspension was cooled in an ice-water bath, followed by slow dropwise addition of concentrated sulfuric acid (27.3 mL, 506 mmol) over 5 min. The reaction mixture was heated to 80 °C and maintained at this temperature for 5 hours. Upon completion of the reaction, the solvent was removed by distillation under reduced pressure and the residue was dissolved in dichloromethane (750 mL). Excess acid was neutralized in small amounts with 5 M aqueous sodium hydroxide solution (200 mL). The aqueous layer was separated and extracted with dichloromethane (250 mL). All organic layers were combined, dried with anhydrous magnesium sulfate, filtered and concentrated to give methyl 3-methylpyrazine-2-carboxylate (16.15 g, 106 mmol, 73% yield). Mass spectral analysis showed m/z = 153 [M + H]+.
References
[1] Patent: US2014/213581, 2014, A1. Location in patent: Paragraph 0773; 0793
[2] Patent: WO2014/138484, 2014, A1. Location in patent: Page/Page column 147; 148
[3] Patent: WO2016/22724, 2016, A1. Location in patent: Page/Page column 292; 293
[4] Patent: WO2016/174073, 2016, A1. Location in patent: Page/Page column 44
[5] Patent: WO2010/130970, 2010, A1. Location in patent: Page/Page column 39-40
3-METHYLPYRAZINE-2-CARBOXYLIC ACID METHYL ESTER Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from 3-METHYLPYRAZINE-2-CARBOXYLIC ACID METHYL ESTER manufacturers
- Product
- 3-METHYLPYRAZINE-2-CARBOXYLIC ACID METHYL ESTER 41110-29-6
- Price
- US $1.00/KG
- Min. Order
- 1KG
- Purity
- 95-99%
- Supply Ability
- 500kg/month
- Release date
- 2019-08-01