4-(2,2,2-TRIFLUOROETHOXY)PHENYLBORONIC ACID
- Product Name
- 4-(2,2,2-TRIFLUOROETHOXY)PHENYLBORONIC ACID
- CAS No.
- 886536-37-4
- Chemical Name
- 4-(2,2,2-TRIFLUOROETHOXY)PHENYLBORONIC ACID
- Synonyms
- (4-(2,2,2-Trifluoroethoxy);4-(2,2,2-trifluoroethoxy)phenyboronic acid;4-(2,2,2-TRIFLUOROETHOXY)PHENYLBORONIC ACID;4-(2,2,2-Trifluoroethoxy)benzeneboronic acid;4-(2,2,2-Trifluoroethoxy)benzeneboronicacid98%;4-(2,2,2-Trifluoroethoxy)benzeneboronic acid 98%;Boronic acid, B-[4-(2,2,2-trifluoroethoxy)phenyl]-;4-(2,2,2-Trifluoroethoxy)benzeneboronic acid, [4-(2,2,2-Trifluoroethoxy)phenyl]boronic acid
- CBNumber
- CB8837293
- Molecular Formula
- C8H8BF3O3
- Formula Weight
- 219.95
- MOL File
- 886536-37-4.mol
4-(2,2,2-TRIFLUOROETHOXY)PHENYLBORONIC ACID Property
- Melting point:
- 191-194℃
- Boiling point:
- 297.1±50.0 °C(Predicted)
- Density
- 1.35±0.1 g/cm3(Predicted)
- storage temp.
- under inert gas (nitrogen or Argon) at 2-8°C
- form
- solid
- pka
- 8.58±0.16(Predicted)
- color
- White
Safety
- Hazard Codes
- Xi
- Hazard Note
- Irritant
- HS Code
- 2931900090
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P405Store locked up.
N-Bromosuccinimide Price
- Product number
- H52889
- Product name
- 4-(2,2,2-Trifluoroethoxy)benzeneboronic acid, 98%
- Packaging
- 250mg
- Price
- $115
- Updated
- 2021/12/16
- Product number
- H52889
- Product name
- 4-(2,2,2-Trifluoroethoxy)benzeneboronic acid, 98%
- Packaging
- 1g
- Price
- $370
- Updated
- 2021/12/16
- Product number
- T795593
- Product name
- 4-(2,2,2-Trifluoroethoxy)phenylboronicAcid
- Packaging
- 50mg
- Price
- $45
- Updated
- 2021/12/16
- Product number
- 6660-3-P7
- Product name
- 4-(2,2,2-Trifluoroethoxy)benzeneboronic acid
- Purity
- 98%
- Packaging
- 250mg
- Price
- $75
- Updated
- 2021/12/16
- Product number
- PC7094
- Product name
- 4-(2,2,2-Trifluoroethoxy)benzeneboronicacid
- Purity
- 98%
- Packaging
- 1g
- Price
- $125
- Updated
- 2021/12/16
4-(2,2,2-TRIFLUOROETHOXY)PHENYLBORONIC ACID Chemical Properties,Usage,Production
Uses
4-(2,2,2-Trifluoroethoxy)phenylboronic acid can be used as organic synthesis intermediate and pharmaceutical intermediate, mainly used in laboratory research and development process and chemical production process.
Synthesis
2- (2,2,2-trifluoroethoxy) bromobenzene 2558, isopropyl borate 2448 and methylTetrahydrofuran 1.5L was added to the reaction flask, and the reaction system was cooled to -15 ° C. 500 mL of isopropylmagnesium chloride in tetrahydrofuran (2.0 M) was added dropwise to the above reaction system and the internal temperature was controlled to not more than -10 ° C, and the reaction was kept at a low temperature for 1 hour. After completion of the reaction, 500 mL of 6M aqueous hydrochloric acid solution was added to terminate the reaction and the ρH- = 2 ~ 3 was added, and the mixture was thoroughly stirred and the aqueous phase was extracted with methyltetrahydrofuran (1.5 LX 1). The combined organic layers were washed with saturated brine (1.5 LX 2), and the combined organic layers were dried over anhydrous sodium sulfate and concentrated to give the crude product of 2- (2,2,2-trifluoroethoxy) phenylboronic acid. The crude product was recrystallized from 770 mL of isopropanol and water (10: 1 by volume) to give 187 g of 2- (2,2,2-trifluoroethoxy) phenylboronic acid in a molar yield of 85%.
4-(2,2,2-TRIFLUOROETHOXY)PHENYLBORONIC ACID Preparation Products And Raw materials
Raw materials
Preparation Products
4-(2,2,2-TRIFLUOROETHOXY)PHENYLBORONIC ACID Suppliers
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- Product
- 4-(2,2,2-TRIFLUOROETHOXY)PHENYLBORONIC ACID 886536-37-4
- Price
- US $34.00-1.20/kg
- Min. Order
- 1kg
- Purity
- 99%
- Supply Ability
- g-kg-tons, free sample is available
- Release date
- 2024-04-08
- Product
- 4-(2,2,2-TRIFLUOROETHOXY)PHENYLBORONIC ACID 886536-37-4
- Price
- US $0.00/kg
- Min. Order
- 1kg
- Purity
- 99.50%
- Supply Ability
- 20tons
- Release date
- 2023-09-14
- Product
- 4-(2,2,2-TRIFLUOROETHOXY)PHENYLBORONIC ACID 886536-37-4
- Price
- US $0.00-0.00/Kg
- Min. Order
- 1Kg
- Purity
- 98%
- Supply Ability
- 2000 Kg
- Release date
- 2023-11-27