1-(1-METHYL-1H-IMIDAZOL-2-YL)-ETHANONE
- Product Name
- 1-(1-METHYL-1H-IMIDAZOL-2-YL)-ETHANONE
- CAS No.
- 85692-37-1
- Chemical Name
- 1-(1-METHYL-1H-IMIDAZOL-2-YL)-ETHANONE
- Synonyms
- 1-Methyl-2-acetylimidazole;2-Acetyl-1-MethyliMidazole;2-Acetyl-1-MethyliMidazol...;1-(1-Methyl-1H-imidazol-2-yl);1-(1-methylimidazol-2-yl)ethanone;1-(1-methyl-2-imidazolyl)ethanone;1-(1-METHYL-1H-IMIDAZOL-2-YL)-ETHANONE;1-(1-Methyl-1H-iMidazol-2-yl)ethan-1-one;ethanone, 1-(1-methyl-1H-imidazol-2-yl)-;Ethanone, 1-(1-methyl-1H-imidazol-2-yl)- (9CI)
- CBNumber
- CB8841986
- Molecular Formula
- C6H8N2O
- Formula Weight
- 124.14
- MOL File
- 85692-37-1.mol
1-(1-METHYL-1H-IMIDAZOL-2-YL)-ETHANONE Property
- Boiling point:
- 105℃ (15 Torr)
- Density
- 1.11±0.1 g/cm3(Predicted)
- storage temp.
- Sealed in dry,Room Temperature
- solubility
- Chloroform (Slightly), Methanol (Slightly)
- form
- Oil
- pka
- 3.92±0.25(Predicted)
- color
- Brown
Safety
- HazardClass
- IRRITANT
- HS Code
- 2933299090
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P280Wear protective gloves/protective clothing/eye protection/face protection.
P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- M313573
- Product name
- 1-(1-Methyl-1H-imidazol-2-yl)ethanone
- Packaging
- 100mg
- Price
- $70
- Updated
- 2021/12/16
- Product number
- 4H56-1-NW
- Product name
- 2-Acetyl-1-methylimidazole
- Packaging
- 250mg
- Price
- $100
- Updated
- 2021/12/16
- Product number
- 3329AC
- Product name
- 1-(1-Methyl-1H-imidazol-2-yl)ethanone
- Packaging
- 100mg
- Price
- $132
- Updated
- 2021/12/16
- Product number
- OR928251
- Product name
- 1-(1-Methyl-1H-imidazol-2-yl)ethan-1-one
- Purity
- 95%
- Packaging
- 250mg
- Price
- $150
- Updated
- 2021/12/16
- Product number
- 3329AC
- Product name
- 1-(1-Methyl-1H-imidazol-2-yl)ethanone
- Packaging
- 250mg
- Price
- $165
- Updated
- 2021/12/16
1-(1-METHYL-1H-IMIDAZOL-2-YL)-ETHANONE Chemical Properties,Usage,Production
Uses
1-(1-Methyl-1H-imidazol-2-yl)ethanone can be used for extensive ligand screening and mechanistic studies.
Synthesis
To a mixture of 1-(1-imidazol-2-yl)ethan-1-one 13 (75 mg, 0.68 mmol, 1.0 eq.) and potassium carbonate (235 mg, 1.7 mmol, 2.5 eq.) was added methyl iodide (47 L, 0.7 mmol, 1.1 eq.) and anhydrous acetonitrile (1.0 mL) under nitrogen. The reaction mixture was stirred at room temperature overnight and monitored by TLC (1.0% methanol/DCM). Acetonitrile was removed on a rotary evaporator and the residue was treated with water (5.0 mL) and extracted with DCM (3 x 5.0 mL). The combined organic extracts were dried with anhydrous sodium sulfate and concentrated on a rotary evaporator to give a brown oil. This was chromatographically separated on silica gel in 0.5-1 methanol/DCM to give 1-(1-methyl-1H-imidazol-2-yl)ethanone as a clarified oil (22 mg, 26%).
1-(1-METHYL-1H-IMIDAZOL-2-YL)-ETHANONE Preparation Products And Raw materials
Raw materials
Preparation Products
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