ChemicalBook > CAS DataBase List > 2-TRIFLUOROMETHYL-PYRIMIDINE-5-CARBALDEHYDE

2-TRIFLUOROMETHYL-PYRIMIDINE-5-CARBALDEHYDE

Product Name
2-TRIFLUOROMETHYL-PYRIMIDINE-5-CARBALDEHYDE
CAS No.
304693-66-1
Chemical Name
2-TRIFLUOROMETHYL-PYRIMIDINE-5-CARBALDEHYDE
Synonyms
2-Trifluoromethyl-5-formylpyrimidine;2-（trifluromethyl）pyridine-5-carbaldehyde;2-TRIFLUOROMETHYL-PYRIMIDINE-5-CARBALDEHYDE;2-Trifluoromethyl-5-pyrimidinecarboxaldehyde;2-(Trifluoromethyl)pyrimidine-5-carbaldehydec;5-Pyrimidinecarboxaldehyde,2-(trifluoromethyl)-;2-TRIFLUOROMETHYL-PYRIMIDINE-5-CARBALDEHYDE ISO 9001：2015 REACH
CBNumber
CB8844523
Molecular Formula
C6H3F3N2O
Formula Weight
176.1
MOL File
304693-66-1.mol
More
Less

2-TRIFLUOROMETHYL-PYRIMIDINE-5-CARBALDEHYDE Property

Boiling point:
153℃
Density 
1.454
Flash point:
47℃
storage temp. 
under inert gas (nitrogen or Argon) at 2-8°C
pka
-3.47±0.22(Predicted)
Appearance
White to light yellow Solid
InChI
InChI=1S/C6H3F3N2O/c7-6(8,9)5-10-1-4(3-12)2-11-5/h1-3H
InChIKey
GAUDQBASERVUGM-UHFFFAOYSA-N
SMILES
C1(C(F)(F)F)=NC=C(C=O)C=N1
More
Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H332Harmful if inhaled

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

More
Less

N-Bromosuccinimide Price

TRC
Product number
T899055
Product name
2-(Trifluoromethyl)pyrimidine-5-carbaldehyde
Packaging
100mg
Price
$65
Updated
2021/12/16
TRC
Product number
T899055
Product name
2-(Trifluoromethyl)pyrimidine-5-carbaldehyde
Packaging
500mg
Price
$220
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
NUC0001597
Product name
2-(TRIFLUOROMETHYL)PYRIMIDINE-5-CARBALDEHYDE
Purity
95.00%
Packaging
250MG
Price
$347.55
Updated
2021/12/16
AK Scientific
Product number
W5289
Product name
2-(Trifluoromethyl)pyrimidine-5-carbaldehyde
Packaging
5g
Price
$611
Updated
2021/12/16
Matrix Scientific
Product number
090160
Product name
2-(Trifluoromethyl)pyrimidine-5-carbaldehyde
Purity
95+%
Packaging
1g
Price
$425
Updated
2021/12/16
More
Less

2-TRIFLUOROMETHYL-PYRIMIDINE-5-CARBALDEHYDE Chemical Properties,Usage,Production

Synthesis

304693-64-9

304693-66-1

Step B: Synthesis of 2-(trifluoromethyl)pyrimidine-5-carbaldehyde To a solution of ethyl 2-(trifluoromethyl)pyrimidine-5-carboxylate (25.5 g, 116.0 mmol) in dichloromethane (580 mL) was slowly added diisobutylaluminum hydride (1.0 M, 130.0 mL, 130.0 mmol) at -78 °C. The reaction mixture was kept stirred at -78 °C for 2 hours. Subsequently, the reaction was quenched by slow addition of hydrochloric acid (2.0 M). The mixture was gradually warmed up to ambient temperature. The mixture was extracted with ether (3 times). The organic phases were combined, dried over anhydrous sodium sulfate, filtered and concentrated to give the target product 2-(trifluoromethyl)pyrimidine-5-carbaldehyde (28.2 g).

References

[1] Patent: US2004/167142, 2004, A1. Location in patent: Page/Page column 23;24
[2] Patent: TW2016/5858, 2016, A. Location in patent: Page/Page column 133; 134
[3] Patent: US2014/107335, 2014, A1. Location in patent: Paragraph 0091; 0092
[4] Bioorganic and Medicinal Chemistry Letters, 2002, vol. 12, # 1, p. 51 - 55
[5] Patent: WO2010/111058, 2010, A1. Location in patent: Page/Page column 69

2-TRIFLUOROMETHYL-PYRIMIDINE-5-CARBALDEHYDE Preparation Products And Raw materials

Raw materials

Sodium hydride Silica gel Ethanol Manganese dioxide Tetrahydrofuran Diethyl ether Ethyl acetate Lithium Aluminum Hydride Dichloromethane Ethyl 3,3-Diethoxypropionate Trifluoroacetamidine

Preparation Products

More
Less

2-TRIFLUOROMETHYL-PYRIMIDINE-5-CARBALDEHYDE Suppliers

China 80 India 2 Ukraine 1 United States 8 Global 91
Weifang Yuda Pharmaceutical Technology Co., Ltd.
Tel
17663603912
Fax
+86-536- 8637276
Email
2710256076@qq.com
Country
China
ProdList
196
Advantage
56
PharmaBlock Sciences (Nanjing),Inc.
Tel
025-86918202 4000255188
Fax
86-025-86918232
Email
sales@pharmablock.com
Country
China
ProdList
5000
Advantage
55
Jia Xing Isenchem Co.,Ltd
Tel
0573-85285100 18627885956
Fax
0573-85285100
Email
isenchem@163.com
Country
China
ProdList
9310
Advantage
66
Shanghai Hanhong Scientific Co.,Ltd.
Tel
021-54306202 13764082696
Email
info@hanhongsci.com
Country
China
ProdList
42934
Advantage
64
Nanjing Vital Chemical Co., Ltd.
Tel
Please Send Email 18652950785
Fax
025-87193546
Email
chemweiao@163.com
Country
China
ProdList
4378
Advantage
65
Shanghai Topbiochem Technology Co., Ltd
Tel
021-58170097
Email
info@topbiochem.com
Country
China
ProdList
9510
Advantage
58
Shanghai T&W Pharmaceutical Co., Ltd.
Tel
+86 21 61551611
Fax
+86 21 50676805
Country
China
ProdList
9891
Advantage
58
Jiangsu Aikon Biopharmaceutical R&D co.,Ltd.
Tel
025-66113011 17798518460
Fax
(1)02557626880
Email
cfzhang@aikonchem.com
Country
China
ProdList
19913
Advantage
55
SynAsst Chemical.
Tel
021-60343070
Fax
021-35122006
Country
China
ProdList
12740
Advantage
55
Shanghai Raise Chemical Technology Co.,Ltd
Tel
+86-021-50935922
Fax
+86-021-33847795
Country
China
ProdList
7865
Advantage
55
Shanghai Chainpharm Bio-medical Technology Co., Ltd.
Tel
+86-021-61727342 13611721451
Fax
021-61294107
Email
chainpharm@163.com
Country
China
ProdList
980
Advantage
58
Shanghai JONLN Reagent Co., Ltd.
Tel
400-0066400 13621662912
Fax
021-55660885
Email
422131432@qq.com
Country
China
ProdList
9979
Advantage
55
Bide Pharmatech Ltd.
Tel
400-164-7117 13681763483
Fax
+86-21-61629029
Email
product02@bidepharm.com
Country
China
ProdList
39966
Advantage
60
Shanghai Worldyang Chemical Co.,Ltd.
Tel
021-021-56795766
Fax
+86-21-56795266
Email
sales@worldyachem.com
Country
China
ProdList
9476
Advantage
58
Shanghai YuYuan Pharmaceutical Co., Ltd.
Tel
13052276172
Fax
13052276172
Email
product@yuyuanpharm.com
Country
China
ProdList
493
Advantage
55
Shanghai Aspire Biological Technology Co., Ltd.
Tel
021-61317773
Fax
021-61486878
Email
sales@aspirebio.com
Country
China
ProdList
2880
Advantage
58
Hangzhou J&H Chemical Co., Ltd.
Tel
0571-87396432
Fax
0571-87396431
Email
sales@jhechem.com
Country
China
ProdList
14912
Advantage
59
Hangzhou Milestone Pharmtech Co., Ltd.
Tel
0571-82896630 18969958410
Email
sales_hz@milestonepharmtech.com
Country
China
ProdList
4895
Advantage
55
Zhengzhou Alfachem Co., Ltd.
Tel
0371-53765687 18937137882
Fax
QQ:2885373884
Email
2853979813@qq.com
Country
China
ProdList
7991
Advantage
55
Nanjing Vital Chemical Co., Ltd.
Tel
025-87193546 18652950785
Fax
025-87193546
Email
chemweiao@163.com
Country
China
ProdList
9021
Advantage
60
Changzhou Hopschain Chemical Co.,Ltd.
Tel
0519-85528066 13775048983
Fax
0519-85528066
Email
sales@hopschem.com
Country
China
ProdList
31553
Advantage
55
parabiochem
Tel
025-83453382-8005
Fax
025-83453382
Email
sale@parabiochem.com
Country
China
ProdList
9595
Advantage
55
Amadis Chemical Company Limited
Tel
571-89925085
Fax
0086-571-89925065
Email
sales@amadischem.com
Country
China
ProdList
131957
Advantage
58
Hangzhou Molcore Biopharmatech Co.,Ltd
Tel
400-711-5280 86-571-81025280
Fax
86-571-85806285
Email
sales@molcore.com
Country
China
ProdList
9967
Advantage
58
Shanghai Haohong Pharmaceutical Co., Ltd.
Tel
400-8210725 400821072
Fax
021-58955996
Email
malulu@leyan.com
Country
China
ProdList
25000
Advantage
58
Zhengzhou Acme Chemical Co., Ltd.
Tel
0371-037163312495,13303845143 13303845143
Fax
QQ3001379618
Email
3001379618@qq.com
Country
China
ProdList
10267
Advantage
58
Shanghai Jizhi Biochemical Technology Co. Ltd.
Tel
4009004166/18616739031 18616739031
Email
3007523370@qq.com
Country
China
ProdList
52687
Advantage
58
Cool Pharm, Ltd
Tel
021-58581007 18019463053
Fax
021-50966098
Email
sales@coolpharm.com
Country
China
ProdList
12878
Advantage
58
Guangdong wengjiang Chemical Reagent Co., Ltd.
Tel
0751-2815688 13927872512
Fax
0751-8963795
Email
3007421951@qq.com
Country
China
ProdList
9939
Advantage
58
Chengdu Feibai Pharmaceutical Co., Ltd.
Tel
028-84641798 18782128315
Email
3302391190@qq.com
Country
China
ProdList
9800
Advantage
55
Allfluoro pharmaceutical co. ltd.
Tel
+86-400-0216110 +86-15958047586
Fax
0086-21-33275002
Email
sales@allfluoro.com
Country
China
ProdList
11385
Advantage
58
Shanghai UCHEM Inc.
Tel
+862156762820 +86-13564624040
Email
sales@myuchem.com
Country
China
ProdList
8460
Advantage
58
Shandong Believe Chemical PTE.LTD
Tel
+86-18553607090 +8618553607090
Email
1093908296@qq.com
Country
China
ProdList
1663
Advantage
58
Hefei TNJ Chemical Industry Co.,Ltd.
Tel
+86-0551-65418684 +8618949823763
Fax
0086-551-65418684
Email
sales@tnjchem.com
Country
China
ProdList
25356
Advantage
58
Dideu Industries Group Limited
Tel
+86-29-89586680 +86-15129568250
Email
1026@dideu.com
Country
China
ProdList
20284
Advantage
58
Unipharm pharmaceutical industry Co., Ltd
Tel
536-8266195 +8613953676784
Email
lee@unipharm-sd.com
Country
China
ProdList
1202
Advantage
58
Dayang Chem (Hangzhou) Co.,Ltd.
Tel
+86-0571-88938639 +8617705817739
Fax
+86-571-88938652，+86-571- 88492614
Email
info@dycnchem.com
Country
China
ProdList
52846
Advantage
58
Hubei Jusheng Technology Co.,Ltd.
Tel
18871490254
Fax
027-59599243
Email
linda@hubeijusheng.com
Country
CHINA
ProdList
28172
Advantage
58
Xi'an Minze Pharmaceutical Technology Co., Ltd
Tel
13981836672
Email
2560370848@qq.com
Country
China
ProdList
2807
Advantage
58
Zhejiang Lianshuo Biotechnology Co., Ltd.
Tel
18616526224
Email
lianshuo@vip.126.com
Country
China
ProdList
9607
Advantage
58
Zhengzhou Edward Biology Co.,Ltd
Tel
0371-63682289 15538176268
Fax
QQ：1875164801
Email
jacschem@163.com
Country
China
ProdList
9926
Advantage
58
Shanghai Longyu Biotechnology Co., Ltd.
Tel
+8619521488211
Fax
+86 15821988213
Email
info@longyupharma.com
Country
China
ProdList
2541
Advantage
58
Qi Qi hang Biotechnology Co., Ltd.
Tel
18151111370
Email
1046215251@qq.com
Country
China
ProdList
5999
Advantage
58
career henan chemical co
Tel
+86-0371-86658258 +8613203830695
Fax
0086-371-86658258
Email
factory@coreychem.com
Country
China
ProdList
29798
Advantage
58
Guangzhou Yuheng Pharmaceutical Technology Co., Ltd
Tel
+8613580539051
Email
joe@yuhengpharm.com
Country
CHINA
ProdList
21142
Advantage
58
Changzhou Kechem Bio-Scientific Co., LTD.
Tel
0519-68985668 13685222090
Fax
qq735434464
Email
sales@kechem.cn
Country
China
ProdList
26028
Advantage
58
Zhende Chemical Technology (Shanghai) Co., Ltd.
Tel
15601952568
Fax
3004479441
Email
sales4@myuchem.com
Country
China
ProdList
2994
Advantage
58
Energy Chemical
Tel
021-58432009 400-005-6266
Fax
021-58436166
Email
marketing1@energy-chemical.com
Country
China
ProdList
44894
Advantage
58
Shanghai Sunway Pharmaceutical Technology Co.,Ltd.
Tel
021-51816796-820 13611835272
Fax
021-5161 3951
Email
sales2@sunwaypharm.com
Country
China
ProdList
44119
Advantage
58
Hubei Wande Chemical Co., Ltd
Tel
027-027-59210159 15377098680
Fax
027-59210159
Email
1148280011@qq.com
Country
China
ProdList
9835
Advantage
58
More
Less

View Lastest Price from 2-TRIFLUOROMETHYL-PYRIMIDINE-5-CARBALDEHYDE manufacturers

Dideu Industries Group Limited
Product
2-TRIFLUOROMETHYL-PYRIMIDINE-5-CARBALDEHYDE 304693-66-1
Price
US $1.10/g
Min. Order
1g
Purity
99.00%
Supply Ability
100 Tons Min
Release date
2021-12-07
Career Henan Chemical Co
Product
2-TRIFLUOROMETHYL-PYRIMIDINE-5-CARBALDEHYDE 304693-66-1
Price
US $2.00/KG
Min. Order
1g
Purity
98%min
Supply Ability
ask
Release date
2020-01-08

304693-66-1, 2-TRIFLUOROMETHYL-PYRIMIDINE-5-CARBALDEHYDERelated Search:

ETHYL 4-HYDROXY-2-(TRIFLUOROMETHYL)PYRIMIDINE-5-CARBOXYLATE Ethyl 4-chloro-2-(trifluoromethyl)pyrimidine-5-carboxylate ETHYL-2-TRIFLUOROMETHYL-4-METHYL-5-PYRIMIDINE CARBOXYLATE ETHYL 4-AMINO-2-(TRIFLUOROMETHYL)PYRIMIDINE-5-CARBOXYLATE ETHYL-2-TRIFLUOROMETHYL-4-CYCLOPROPYL-5-PYRIMIDINE CARBOXYLATE ETHYL-2-TRIFLUOROMETHYL-4-TRIFLUOROMETHYL-5-PYRIMIDINE CARBOXYLATE ETHYL-2-TRIFLUOROMETHYL-4-PHENYL-5-PYRIMIDINE CARBOXYLATE ETHYL-2-TRIFLUOROMETHYL-4-(2-METHOXYPHENYL)-5-PYRIMIDINE CARBOXYLATE ETHYL-2-TRIFLUOROMETHYL-4-PROPYL-5-PYRIMIDINE CARBOXYLATE ETHYL-2-TRIFLUOROMETHYL-4-(2-BROMOPHENYL)-5-PYRIMIDINE CARBOXYLATE ETHYL-2-TRIFLUOROMETHYL-4-(2-METHYLPHENYL)-5-PYRIMIDINE CARBOXYLATE ETHYL-2-TRIFLUOROMETHYL-4-ISOPROPYL-5-PYRIMIDINE CARBOXYLATE ETHYL-2-TRIFLUOROMETHYL-4-ETHYL-5-PYRIMIDINE CARBOXYLATE ETHYL-2-TRIFLUOROMETHYL-4-(2-IODOPHENYL)-5-PYRIMIDINE CARBOXYLATE SODIUM 5-(ETHOXYCARBONYL)-2-(TRIFLUOROMETHYL)PYRIMIDIN-4-OLATE ETHYL 4-(2-[(2,6-DICHLORO-4-PYRIDYL)CARBONYL]HYDRAZINO)-2-(TRIFLUOROMETHYL)PYRIMIDINE-5-CARBOXYLATE ETHYL 4-HYDRAZINO-2-(TRIFLUOROMETHYL)PYRIMIDINE-5-CARBOXYLATE ETHYL-2-TRIFLUOROMETHYL-4-(2-CHLOROPHENYL)-5-PYRIMIDINE CARBOXYLATE

  • 2-TRIFLUOROMETHYL-PYRIMIDINE-5-CARBALDEHYDE
  • 2-(Trifluoromethyl)pyrimidine-5-carbaldehydec
  • 2-Trifluoromethyl-5-formylpyrimidine
  • 2-Trifluoromethyl-5-pyrimidinecarboxaldehyde
  • 2-（trifluromethyl）pyridine-5-carbaldehyde
  • 5-Pyrimidinecarboxaldehyde,2-(trifluoromethyl)-
  • 2-TRIFLUOROMETHYL-PYRIMIDINE-5-CARBALDEHYDE ISO 9001：2015 REACH
  • 304693-66-1
  • C6H3F3N2O
  • Fluorine series