ChemicalBook > CAS DataBase List > 1,3-Benzodioxole-5-acetic acid methyl ester

1,3-Benzodioxole-5-acetic acid methyl ester

Product Name
1,3-Benzodioxole-5-acetic acid methyl ester
CAS No.
326-59-0
Chemical Name
1,3-Benzodioxole-5-acetic acid methyl ester
Synonyms
NSC 105308;ASISCHEM D13375;Methyl 1,3-Benzodioxole-5-acetate;Methyl 1,3-benzodioxol-5-ylacetate;methyl2-(1,3-benzodioxol-5-yl)acetate;Methyl 2-(1,3-dioxaindan-5-yl)acetate;Methyl 4,5-(Methylenedioxy)phenylacetate;Methyl (3,4-Methylenedioxyphenyl)acetate;Methyl 2-(2H-1,3-benzodioxol-5-yl)acetate;Methyl 2-(benzo[d][1,3]dioxol-5-yl)acetate
CBNumber
CB8847625
Molecular Formula
C10H10O4
Formula Weight
194.18
MOL File
326-59-0.mol
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1,3-Benzodioxole-5-acetic acid methyl ester Property

Boiling point:
278.3℃
Density 
1.265
refractive index 
1.5430 (estimate)
Flash point:
120.0℃
InChI
InChI=1S/C10H10O4/c1-12-10(11)5-7-2-3-8-9(4-7)14-6-13-8/h2-4H,5-6H2,1H3
InChIKey
HEMYXNDMAAOTCK-UHFFFAOYSA-N
SMILES
O1C2=CC=C(CC(OC)=O)C=C2OC1
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Safety

HazardClass 
IRRITANT
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P321Specific treatment (see … on this label).

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P362Take off contaminated clothing and wash before reuse.

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N-Bromosuccinimide Price

TRC
Product number
B203480
Product name
1,3-Benzodioxole-5-aceticAcidMethylEster
Packaging
2g
Price
$155
Updated
2021/12/16
Biosynth Carbosynth
Product number
FB18215
Product name
1,3-Benzodioxole-5-acetic acid methyl ester
Packaging
1g
Price
$170
Updated
2021/12/16
Biosynth Carbosynth
Product number
FB18215
Product name
1,3-Benzodioxole-5-acetic acid methyl ester
Packaging
2g
Price
$300
Updated
2021/12/16
Biosynth Carbosynth
Product number
FB18215
Product name
1,3-Benzodioxole-5-acetic acid methyl ester
Packaging
250mg
Price
$75
Updated
2021/12/16
Matrix Scientific
Product number
058248
Product name
Methyl 2-(2H-1,3-benzodioxol-5-yl)acetate
Purity
>95%
Packaging
500mg
Price
$77
Updated
2021/12/16
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1,3-Benzodioxole-5-acetic acid methyl ester Chemical Properties,Usage,Production

Uses

Methyl 1,3-benzodioxol-5-ylacetate is a reagent used to prepare pharmaceutically active Benzodioxole derivatives.

Preparation

1,3-Benzodioxole-5-acetic acid methyl ester is a lignan synthesized by the condensation of podophyllotoxin with acetone in the presence of an acid catalyst.

Mode of action

1,3-Benzodioxole-5-acetic acid methyl ester is a regioselective inhibitor of 5α→5β conversion. This inhibition leads to a decrease in the production of diene metabolites that may be carcinogenic, as well as a decrease in the production of podophyllotoxin and its derivatives (podophyllum alkaloids). It has been shown to have anti-inflammatory properties and to inhibit prostaglandin synthesis.

1,3-Benzodioxole-5-acetic acid methyl ester Preparation Products And Raw materials

Raw materials

Preparation Products

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1,3-Benzodioxole-5-acetic acid methyl ester Suppliers

Canada 1 China 32 India 2 United Kingdom 1 United States 5 Global 41
Carbosynth
Tel
--
Fax
--
Email
sales@carbosynth.com
Country
United Kingdom
ProdList
6005
Advantage
58
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View Lastest Price from 1,3-Benzodioxole-5-acetic acid methyl ester manufacturers

Anhui Yiao New Material Technology Co., Ltd
Product
methyl 1,3-benzodioxol-5-ylacetate 326-59-0
Price
US $0.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
1 ton
Release date
2023-08-14
Anhui Yiao New Material Technology Co., Ltd
Product
methyl 1,3-benzodioxol-5-ylacetate 326-59-0
Price
US $0.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
1 ton
Release date
2023-08-14
Wuhan Boyuan Import & Export Co., LTD
Product
methyl 1,3-benzodioxol-5-ylacetate 326-59-0
Price
US $25.00/kg
Min. Order
1kg
Purity
99.96%
Supply Ability
500kg
Release date
2023-04-28

326-59-0, 1,3-Benzodioxole-5-acetic acid methyl esterRelated Search:

Ethyl Benzo[1,3]dioxol-5-yl-difluoroacetate 1,3-Benzodioxole-5-acetic acid methyl ester CI 1020 2-(2,2-DIFLUOROBENZODIOXOL-5-YL)-MALONIC ACID DIMETHYL ESTER ETHYL 3,4-METHYLENEDIOXYBENZOYLFORMATE 3-AMINO-2-BENZO[1,3]DIOXOL-5-YL-PROPIONIC ACID ETHYL ESTER RARECHEM AK ML 0122 2-BENZO[1,3]DIOXOL-5-YL-PROPIONIC ACID METHYL ESTER

  • BENZO[1,3]DIOXOL-5-YL-ACETIC ACID METHYL ESTER
  • ASISCHEM D13375
  • 1,3-Benzodioxole-5-acetic Acid Methyl Ester
  • Methyl 2-(2H-1,3-benzodioxol-5-yl)acetate
  • [3,4-(Methylenedioxy)phenyl]acetic Acid Methyl Ester
  • Methyl (3,4-Methylenedioxyphenyl)acetate
  • Methyl 1,3-Benzodioxole-5-acetate
  • Methyl 4,5-(Methylenedioxy)phenylacetate
  • NSC 105308
  • Methyl 1,3-benzodioxol-5-ylacetate
  • methyl2-(1,3-benzodioxol-5-yl)acetate
  • METHYL 1,3-BENZODIOXOL-5-YLACETATE ISO 9001：2015 REACH
  • Methyl 2-(1,3-dioxaindan-5-yl)acetate
  • Methyl 2-(benzo[d][1,3]dioxol-5-yl)acetate
  • 326-59-0
  • Aromatics
  • Heterocycles
  • Intermediates & Fine Chemicals
  • Pharmaceuticals
  • intermediate