L371,257

Product Name: L371,257
CAS No.: 162042-44-6
Chemical Name: L371,257
Synonyms: 257;L-371;L371,257;L371,257,L 371,257;1-[1-[4-(1-acetylpiperidin-4-yl)oxy-2-methoxybenzoyl]piperidin-4-yl]-4H-3,1-benzoxazin-2-one;1-[4-[(1-Acetyl-4-piperidinyl)oxy]-2-methoxybenzoyl]-4-(2-oxo-2H-3,1-benzoxazin-1(4H)-yl)piperidine;2H-3,1-Benzoxazin-2-one, 1-[1-[4-[(1-acetyl-4-piperidinyl)oxy]-2-methoxybenzoyl]-4-piperidinyl]-1,4-dihydro-
CBNumber: CB8850593
Molecular Formula: C28H33N3O6
Formula Weight: 507.58
MOL File: 162042-44-6.mol

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L371,257 Property

Boiling point:: 728.9±60.0 °C(Predicted)
Density: 1.282±0.06 g/cm3(Predicted)
storage temp.: Store at RT
solubility: Soluble to 10 mM in DMSO with gentle warming
form: Powder
pka: 0.73±0.20(Predicted)
color: White to off-white

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Tocris

Product number: 2410
Product name: L-371,257
Purity: ≥99%(HPLC)
Packaging: 10
Price: $269
Updated: 2021/12/16

Usbiological

Product number: 255632
Product name: L-371,257
Packaging: 10mg
Price: $516
Updated: 2021/12/16

TRC

Product number: L352940
Product name: L-371,257
Packaging: 1mg
Price: $160
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: API0009977
Product name: L-371,257
Purity: 95.00%
Packaging: 25MG
Price: $4025
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: API0009977
Product name: L-371,257
Purity: 95.00%
Packaging: 50MG
Price: $7650
Updated: 2021/12/16

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L371,257 Chemical Properties,Usage,Production

Uses

L-371,257 is a potent antagonist of oxytocin-induced contractions of the rat uterus in vitro and in vivo and has significant oral bioavailability in rats.

Biological Activity

Potent, high affinity human oxytocin (OT) receptor antagonist (K i = 4.6 nM) that displays > 800-fold selectivity over human arginine vasopressin receptors V 1a and V 2 . Antagonizes oxytocin-induced contractions in isolated rat uterine tissue (pA 2 = 8.44) and in anesthetised rats following intravenous and intraduodenal administration. Orally active.

storage

Store at RT

L371,257 Preparation Products And Raw materials

Raw materials

Preparation Products

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L371,257 Suppliers

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162042-44-6, L371,257Related Search:

4-Cbz-Aminopiperidine 1-Acetyl-4-(methylamino)piperidine 4-Methoxysalicylamide 4-(4-METHYLPHENOXY)PIPERIDINE HYDROCHLORIDE 4-PHENOXYPIPERIDINE 4-[3-(Dimethylamino)propoxy]benzaldehyde 1-(4-ISOPROPOXYPHENYL)METHANAMINE 2,4-Dihydroxybenzamide 4-ANILINO-1-BENZYLPIPERIDINE 4-(3-METHOXYPHENOXY)PIPERIDINE 1-Acetylpiperidin-4-amine 4-(PIPERIDIN-4-YLOXY)BENZAMIDE (4-AMINO-PIPERIDIN-1-YL)-PHENYL-METHANONE Benzamide, N-(3-dimethylaminopropyl)-p-propoxy- 4-ETHOXY-N,N-DIETHYLBENZAMIDE CHEMBRDG-BB 9072047 4-AMINOCARBETHOXYPIPERIDINE 1-ACETYLPIPERIDIN-4-OL

L371,257

1-[4-[(1-Acetyl-4-piperidinyl)oxy]-2-methoxybenzoyl]-4-(2-oxo-2H-3,1-benzoxazin-1(4H)-yl)piperidine

1-[1-[4-(1-acetylpiperidin-4-yl)oxy-2-methoxybenzoyl]piperidin-4-yl]-4H-3,1-benzoxazin-2-one

2H-3,1-Benzoxazin-2-one, 1-[1-[4-[(1-acetyl-4-piperidinyl)oxy]-2-methoxybenzoyl]-4-piperidinyl]-1,4-dihydro-

257

L-371

L371,257,L 371,257

162042-44-6

C28H33N3O6