RAC-TRANS-5-HYDROXY-1,3-OXATHIOLANE-2-CARBOXYLIC ACID Property

Melting point:

>87°C (dec.)

Boiling point:

434.9±45.0 °C(Predicted)

Density 

1.697±0.06 g/cm3(Predicted)

storage temp. 

Refrigerator

solubility 

DMSO (Slightly), Methanol (Slightly)

pka

2.13±0.40(Predicted)

form 

Solid

color 

Off-White to Light Brown

Stability:

Epimerize in solution

Safety

Hazard Codes 

Xn

Risk Statements 

22-38-41-43

Safety Statements 

22-24-26-37/39

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Danger

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H317May cause an allergic skin reaction

H318Causes serious eye damage

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P272Contaminated work clothing should not be allowed out of the workplace.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P310Immediately call a POISON CENTER or doctor/physician.

P321Specific treatment (see … on this label).

P330Rinse mouth.

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P333+P313IF SKIN irritation or rash occurs: Get medical advice/attention.

P362Take off contaminated clothing and wash before reuse.

P363Wash contaminated clothing before reuse.

P501Dispose of contents/container to..…

RAC-TRANS-5-HYDROXY-1,3-OXATHIOLANE-2-CARBOXYLIC ACID Chemical Properties,Usage,Production

Uses

5-Hydroxy-1,3-oxathiolane-2-carboxylic Acid is used in the synthesis of potent antiviral agent (-)-2’-Deoxy-3’-thiacytidine and its enantiomer.