(3R,4S)-1-Benzoyl-3-(1-ethoxyethoxy)-4-phenyl-2-azetidinone

Product Name: (3R,4S)-1-Benzoyl-3-(1-ethoxyethoxy)-4-phenyl-2-azetidinone
CAS No.: 201856-53-3
Chemical Name: (3R,4S)-1-Benzoyl-3-(1-ethoxyethoxy)-4-phenyl-2-azetidinone
Synonyms: Paclitaxel side chains;SIDE CHAINS OF PACLITAXEL--1;(3R,4S)-1-Benzoyl-3-(2-Ethoxye;1-benzoyl-3-(1-ethoxyethoxy)-4-phenyl-2-azetidinone;(3R,4S)-3-(1-ethoxyethoxy)-4-phenyl-N-benzoyl-2-azetidinone;(3R,4S)-1-Benzoyl-3-(1-ethoxyethoxy)-4-phenyl-2-azetidinone;(3R,4S)-1-benzoyl-3-(1-ethoxyethoxy)-4-phenylazetidin-2-one;(3R,4S)-1-BENZOYL-3-(2-ETHOXYETHOXYL)-4-PHENYL-2-AZETIDINONE;2-Azetidinone,1-benzoyl-3-(1-ethoxyethoxy)-4-phenyl-, (3R,4S)-;(3R,4S)-1-Benzoyl-3-(1-Ethoxyethoxy)-4-Phenyl-2-AzetidinoneCasNo.
CBNumber: CB8854814
Molecular Formula: C20H21NO4
Formula Weight: 339.39
MOL File: 201856-53-3.mol

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(3R,4S)-1-Benzoyl-3-(1-ethoxyethoxy)-4-phenyl-2-azetidinone Property

Boiling point:: 464.8±55.0 °C(Predicted)
Density: 1.22
storage temp.: 2-8°C
pka: -4.83±0.60(Predicted)
CAS DataBase Reference: 201856-53-3(CAS DataBase Reference)

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P321Specific treatment (see … on this label).

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P362Take off contaminated clothing and wash before reuse.

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N-Bromosuccinimide Price

Biosynth Carbosynth

Product number: FB148182
Product name: (3R,4S)-1-Benzoyl-3-(1-ethoxyethoxy)-4-phenyl-2-azetidinone
Packaging: 50mg
Price: $63
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FB148182
Product name: (3R,4S)-1-Benzoyl-3-(1-ethoxyethoxy)-4-phenyl-2-azetidinone
Packaging: 100mg
Price: $110
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FB148182
Product name: (3R,4S)-1-Benzoyl-3-(1-ethoxyethoxy)-4-phenyl-2-azetidinone
Packaging: 250mg
Price: $220
Updated: 2021/12/16

AK Scientific

Product number: Q749
Product name: (3R,4S)-1-Benzoyl-3-(1-ethoxyethoxy)-4-phenyl-2-azetidinone
Packaging: 250mg
Price: $347
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FB148182
Product name: (3R,4S)-1-Benzoyl-3-(1-ethoxyethoxy)-4-phenyl-2-azetidinone
Packaging: 500mg
Price: $380
Updated: 2021/12/16

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(3R,4S)-1-Benzoyl-3-(1-ethoxyethoxy)-4-phenyl-2-azetidinone Chemical Properties,Usage,Production

Uses

(3R,4S)-1-Benzoyl-3-(1-ethoxyethoxy)-4-phenyl-2-azetidinone is an investigational intermediate chemical for Paclitaxel and Docetaxel.

Synthesis

To a solution of 2.35 g (10 mmol) of cis-3-(1-ethoxyethoxy)-4-phenylazetidin-2-one in 40 mL of THF at -78° C, was added 6.1 mL (10.07 mmol) of a 1.65M solution of n-butyllithium in hexane. The mixture was stirred for 10 min at -78° C and a solution of 1.42 g (10.1 mmol) of benzoyl chloride in 10 mL of THF was added. The mixture was stirred at -78° C for 1 h diluted with 70 mL of saturated aqueous sodium bicarbonate and extracted with three 50 mL portions of ethyl acetate. The combined ethyl acetate extracts were dried over sodium sulfate and concentrated to give 3.45 g of oil. Chromatography of the oil on silica gel eluted with ethyl acetate/hexane gave 3.22 g (95%) of (3R,4S)-1-Benzoyl-3-(1-ethoxyethoxy)-4-phenyl-2-azetidinone as a colorless oil.

(3R,4S)-1-Benzoyl-3-(1-ethoxyethoxy)-4-phenyl-2-azetidinone Preparation Products And Raw materials

Raw materials

Preparation Products

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(3R,4S)-1-Benzoyl-3-(1-ethoxyethoxy)-4-phenyl-2-azetidinone Suppliers

China 63 Europe 2 Germany 1 United Kingdom 3 United States 7 Global 76

XiaoGan ShenYuan ChemPharm co,ltd

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View Lastest Price from (3R,4S)-1-Benzoyl-3-(1-ethoxyethoxy)-4-phenyl-2-azetidinone manufacturers

Sinoway Industrial co., ltd.

Product: (3R,4S)-1-Benzoyl-3-(1-ethoxyethoxy)-4-phenyl-2-azetidinone 201856-53-3
Price: US $0.00/Kg/Bag
Min. Order: 2Kg/Bag
Purity: 99% up, High Density
Supply Ability: 20 tons
Release date: 2021-08-12

Longyan Tianhua Biological Technology Co., Ltd

Product: (3R,4S)-1-Benzoyl-3-(1-ethoxyethoxy)-4-phenyl-2-azetidinone 201856-53-3
Price: US $63.00/KG
Min. Order: 1KG
Purity: 99
Supply Ability: 1000KG
Release date: 2020-11-17

Career Henan Chemical Co

Product: (3R,4S)-1-Benzoyl-3-(1-ethoxyethoxy)-4-phenyl-2-azetidinone 201856-53-3
Price: US $7.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 100KG
Release date: 2020-02-13

201856-53-3, (3R,4S)-1-Benzoyl-3-(1-ethoxyethoxy)-4-phenyl-2-azetidinoneRelated Search:

PHENYL VALERATE 2-Ethoxyethanol Ethoxyethyne Diethoxymethyl acetate Benzoyl peroxide Benzoyl chloride Ethyl vinyl ether Ethoxyquin DIETHOXYMETHANE PHENYL RESIN Phenylacetic acid (3R,4S)-3-Hydroxy-4-phenyl-2-azetidinone Docetaxel Cyclobutanone 2-Azetidinone Docetaxel PACLITAXEL SIDE CHAIN NO 1 Paclitaxel

(3R,4S)-1-Benzoyl-3-(1-ethoxyethoxy)-4-phenyl-2-azetidinone

(3R,4S)-1-Benzoyl-3-(1-Ethoxyethoxy)-4-Phenyl-2-AzetidinoneCasNo.

(3R,4S)-1-BENZOYL-3-(2-ETHOXYETHOXYL)-4-PHENYL-2-AZETIDINONE

1-benzoyl-3-(1-ethoxyethoxy)-4-phenyl-2-azetidinone

Paclitaxel side chains

(3R,4S)-3-(1-ethoxyethoxy)-4-phenyl-N-benzoyl-2-azetidinone

2-Azetidinone,1-benzoyl-3-(1-ethoxyethoxy)-4-phenyl-, (3R,4S)-

(3R,4S)-1-Benzoyl-3-(2-Ethoxye

DOCETAXEL SIDE CHAIN / (3R,4S)-1-BENZOYL-3-(2-ETHOXYETHOXY)-4-PHENYL-2-PHENYL-AZETIDIONE

(3R,4S)-1-BENZOYL-3-(2-ETHOXYETHOXYL) -4-PHENYL-2-AZETIDINONE 97%

SIDE CHAINS OF PACLITAXEL--1

(3R,4S)-1-benzoyl-3-(1-ethoxyethoxy)-4-phenylazetidin-2-one

Paclitaxel Side Chain (Azelidinone) 1-Benzoyl-3-(1-Ethoxyethoxy)-4-Phenyl-2-Azetidinone

(3R, 4S) -1-Benzoyl-3- (1-ethoxyethoxy) -4-phenyl-2-azacyclobutanone

201856-53-3

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