4-Hydroxy-2-methyl-2H-1,2-benzothiazine-3-carboxylic acid isopropyl ester 1,1-dioxide

Product Name: 4-Hydroxy-2-methyl-2H-1,2-benzothiazine-3-carboxylic acid isopropyl ester 1,1-dioxide
CAS No.: 118854-48-1
Chemical Name: 4-Hydroxy-2-methyl-2H-1,2-benzothiazine-3-carboxylic acid isopropyl ester 1,1-dioxide
Synonyms: Piroxicam EP IMP L;PiroxicaM iMpurity L;MeloxicaM IMpurity F;Meloxicam Impurity F(EP);Meloxicam EP Impurity F(EP);Isopropyl 4-Hydroxy-2-methyl-;Meloxicam USP Related Compound C;1-Methylethyl 4-Hydroxy-2-methyl-2H;Meloxicam EP Impurity F (Piroxicam EP Impurity L);Piroxicam EP Impurity L (Meloxicam EP Impurity F)
CBNumber: CB8854915
Molecular Formula: C13H15NO5S
Formula Weight: 297.33
MOL File: 118854-48-1.mol

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4-Hydroxy-2-methyl-2H-1,2-benzothiazine-3-carboxylic acid isopropyl ester 1,1-dioxide Property

Melting point:: 200 °C
Boiling point:: 450.5±55.0 °C(Predicted)
Density: 1.408
storage temp.: -20°C Freezer, Under inert atmosphere
solubility: Chloroform (Slightly), Methanol (Slightly)
pka: 4.50±1.00(Predicted)
color: White to Off-White

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Safety

Hazard Codes: Xi
Risk Statements: 36/37/38
Safety Statements: 26
HS Code: 2934990002

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Danger

Hazard statements

H301Toxic if swalloed

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P301+P310IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.

P405Store locked up.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 1379434
Product name: Meloxicam Related Compound C
Packaging: 30mg
Price: $1580
Updated: 2024/03/01

TRC

Product number: I824600
Product name: Isopropyl4-Hydroxy-2-methyl-2H-1,2-benzothiazine-3-carboxylate1,1-Dioxide(PiroxicamImpurityL)
Packaging: 10mg
Price: $180
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: API0027977
Product name: ISOPROPYL-4-HYDROXY-2-METHYL-2H-1,2-BENZOTHIAZINE-3-CARBOXYLATE-1,1-DIOXIDE
Purity: 95.00%
Packaging: 5MG
Price: $497.95
Updated: 2021/12/16

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4-Hydroxy-2-methyl-2H-1,2-benzothiazine-3-carboxylic acid isopropyl ester 1,1-dioxide Chemical Properties,Usage,Production

Uses

Piroxicam Impurity L. Also an impurity found in meloxicam (M216100). Meloxicam USP Related Compound C.

4-Hydroxy-2-methyl-2H-1,2-benzothiazine-3-carboxylic acid isopropyl ester 1,1-dioxide Preparation Products And Raw materials

Raw materials

Preparation Products

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4-Hydroxy-2-methyl-2H-1,2-benzothiazine-3-carboxylic acid isopropyl ester 1,1-dioxide Suppliers

Canada 1 China 71 India 14 Ukraine 1 United Kingdom 1 United States 10 Global 98

Toronto Research Chemicals

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118854-48-1, 4-Hydroxy-2-methyl-2H-1,2-benzothiazine-3-carboxylic acid isopropyl ester 1,1-dioxideRelated Search:

2-METHYL-4-HYDROXY-2H-1,2-BENZOTHIAZINE-3-CARBOXYLIC METHYL ESTER-1,1-DIOXIDE 2-[(5-Methyl-2-thiazolyl)amino]-2-oxoacetic Acid 5Carboxy Meloxicam Meloxicam EP Impurity D 2H-1,2-Benzothiazine-3-carboxaMide, 4-Methoxy-2-Methyl-N-(5-Methyl-2-thiazolyl)-, 1,1-dioxide Benzoic acid, 2-[(methylamino)sulfonyl]- Meloxicam Impurity 1 HCl 5Hydroxy Meloxicam 5-(2-Aminopropyl)-1-[3-(benzoyloxy)propyl]-2,3-dihydro-1H-indole-7-carbonitrile Piroxicam Formic acid isopropyl ester 4-Hydroxy-2-methyl-2H-1,2-benzothiazine-3-carboxylic acid isopropyl ester 1,1-dioxide 2-Methyl-4-hydroxy-2H-1,2-benzothiazine-3-carboxylic acid ethyl ester 1,1-dioxide Methyl 4-hydroxy-2H-1,2-benzothiazine-3-carboxylate 1,1-dioxide

Isopropyl-4-hydroxy-2-methyl-2H-1,2-benzothiazine-3-carboxylate-1,1-dioxide

4-HYDROXY-2-METHYL-1H-1,2-BENZOTHIAZINE-3-CARBOXYLICACIDISOPROPYLESTER-1,1-DIOXIDE

4-hydroxy-2-methyl-2H-1,2-benzothiazine-3-carboxylic acid isopropylester-1,1-dioxide (intermediate of piroxicam)

Isopropyl 2-methyl-4-hydroxy-2H-1,2-benzothiazine-3-carboxylater 1,1-dioxide

Isopropyl 4-Hydroxy-2-methyl-2H-1,2-benzothiazine-3-carboxylate 1,1-Dioxide (Piroxicam Impurity L)

Isopropyl 4-Hydroxy-2-methyl-

Meloxicam Related Compound C (30 mg) (Isopropyl 4-hydroxy-2-methyl-2H-1,2-benzothiazine-3-carboxylate-1,1-dioxide)

MeloxicaM IMpurity F

Isopropyl 4-Hydroxy-2-methyl- (Piroxicam Impurity L)

PiroxicaM iMpurity L

isopropyl 4-hydroxy-2-methyl-2H-benzo[e][1,2]thiazine-3-carboxylate 1,1-dioxide

Meloxicam Impurity F(EP)

4-Hydroxy-2-methyl-2H-1,2-benzothiazine-3-carboxylic acid isopropyl ester 1,1-dioxide

Imp. F (EP): Isopropyl4-Hydroxy-2-methyl-2H-1,2-benzothiazine-3-carboxylate1,1-Dioxide(1-Methylethyl4-Hydroxy-2-methyl-2H-1,2-benzothiazine-3-carboxylate 1,1-Dioxide)

propan-2-yl 4-hydroxy-2-methyl-1,1-dioxo-1λ<sup>6</sup>,2-benzothiazine-3-carboxylate

Meloxicam EP Impurity F (Piroxicam EP Impurity L)

Piroxicam EP Impurity L (Meloxicam EP Impurity F)

1-Methylethyl 4-Hydroxy-2-methyl-2H

2H-1,2-Benzothiazine-3-carboxylic acid, 4-hydroxy-2-methyl-, 1-methylethyl ester, 1,1-dioxide

Piroxicam EP Impurity L (Meloxicam EP Impurity F/ Meloxicam Related Compund C)

Meloxicam EP Impurity F/ Meloxicam Related Compund C (Piroxicam EP Impurity L)

4-Hydroxy-2-methyl-2H-1,2-benzothiazine-3-carboxylic acid is...

Meloxicam EP Impurity F(EP)

Meloxicam USP Related Compound C

Isopropyl 4-hydroxy-2-methyl-2H-benzo[e][1,2]thiazine-3-carboxylate 1,1-dioxide (Meloxicam Impurity)

Meloxicam EP Impurity F Meloxicam USP Related Compound C

Isopropyl 4-hydroxy-2-methyl-2H-1,2-benzothiazole-1, 1-Dioxide-3-Carboxylic Acid Ester

Piroxicam EP IMP L

Piroxicam EP Impurity L (Meloxicam EP Impurity F, Meloxicam USP Related Compound C)

Piroxicam EP Impurity L 1-methylethyl 4-hydroxy-2-methyl-2H-1,2-benzothiazine-3- carboxylate 1,1-dioxide

118854-48-1

Aromatics

Impurities

Intermediates & Fine Chemicals

Pharmaceuticals

Sulfur & Selenium Compounds

Organic acids

(intermediate of piroxicam)