hexafluronium bromide
- Product Name
- hexafluronium bromide
- CAS No.
- 317-52-2
- Chemical Name
- hexafluronium bromide
- Synonyms
- Milaxen;Mylaxen;Hexafluorenium;Esafluronio bromuro;HexafluoreniumBromide;hexafluronium bromide;Hexafluorenium dibromide
- CBNumber
- CB8898197
- Molecular Formula
- C36H42Br2N2
- Formula Weight
- 662.54008
- MOL File
- 317-52-2.mol
hexafluronium bromide Property
- Melting point:
- 188-189°
- Density
- 1.1954 (rough estimate)
- refractive index
- 1.6800 (estimate)
N-Bromosuccinimide Price
- Product number
- H294415
- Product name
- HexafluoreniumBromide
- Packaging
- 10g
- Price
- $1320
- Updated
- 2021/12/16
- Product number
- API0002908
- Product name
- HEXAFLUORENIUM BROMIDE
- Purity
- 95.00%
- Packaging
- 5MG
- Price
- $500.43
- Updated
- 2021/12/16
hexafluronium bromide Chemical Properties,Usage,Production
Originator
Mylaxen,Mallinckrodt
Uses
Relaxant (skeletal muscle); synergist (succinylcholine).
Uses
Hexafluorenium Bromide is a cholinesterase inhibitor.
Manufacturing Process
2 Methods of producing of hexamethylene bis(2-fluorenyldimethylammonium)
dibromide:
1. To a solution of 13.2 g (0.054 mole) of 9-bromofluorene in 200 ml of
acetonitrile was added 3.1 g (0.018 mole) of 1,6-bis(dimethylamino)hexane.
Heat was evolved and solid began to precipitate immediately. After the initial
reaction had subsided the mixture was refluxed for 3.5 h on a steam bath.
The solid was collected and recrystallized three times from propanol to give
10.66 g (89% of the theoretical yield based on alkylenediamine) of
hexamethylene bis(9-fluorenyldimethylammonium) dibromide, as white
crystals melting at 188°-189°C.
2. A mixture of 4.18 g (0.02 mole) of 2-dimethylaminofluorene and 1.22 g
(0.005 mole) of 1,6-dibromohexane was heated at 115°C for 24 h, after
which time 10 ml of dry dioxane was added and the mixture refluxed for an
additional 37 h. The solid was filtered off washed with hot acetonitrile and
twice recrystallized from propanol to give 0.45 g of hexamethylene bis(2-
fluorenyldimethylammonium) dibromide, melting at 220°-222°C.
brand name
Mylaxen (Medpointe).
Therapeutic Function
Muscle relaxant
hexafluronium bromide Preparation Products And Raw materials
Raw materials
Preparation Products
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