5,6,7,8-tetrahydroquinazoline-2,4-diamine

5,6,7,8-tetrahydroquinazoline-2,4-diamine Property

Melting point:

240-242 °C

Boiling point:

445.2±55.0 °C(Predicted)

Density 

1.290±0.06 g/cm3(Predicted)

pka

8.08±0.20(Predicted)

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

5,6,7,8-tetrahydroquinazoline-2,4-diamine Chemical Properties,Usage,Production

Uses

5,6,7,8-Tetrahydroquinazoline-2,4-diamine-15N3 is an isotopically labelled analog of 5,6,7,8-Tetrahydroquinazoline-2,4-diamine (CAS# 1899-40-7), which is a potent inhibitor of dihydrofolate reductase (DHFR).