ChemicalBook > CAS DataBase List > nifurfoline
nifurfoline
- Product Name
- nifurfoline
- CAS No.
- 3363-58-4
- Chemical Name
- nifurfoline
- Synonyms
- nifurfoline;3-[(Morpholino)methyl]-1-[(5-nitrofurfurylidene)amino]hydantoin;2,4-Imidazolidinedione, 3-(4-morpholinylmethyl)-1-[[(5-nitro-2-furanyl)methylene]amino]-;3-(morpholin-4-ylmethyl)-1-[(E)-(5-nitrofuran-2-yl)methylideneamino]imidazolidine-2,4-dione
- CBNumber
- CB8911340
- Molecular Formula
- C13H15N5O6
- Formula Weight
- 337.29
- MOL File
- 3363-58-4.mol
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nifurfoline Property
- Melting point:
- 206°; also reported as mp 194-196°
- Boiling point:
- 486.5±55.0 °C(Predicted)
- Density
- 1.63±0.1 g/cm3(Predicted)
- pka
- 5.39±0.10(Predicted)
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nifurfoline Chemical Properties,Usage,Production
Originator
Furobactil,Carrion,France,1974
Definition
ChEBI: Nifurfoline is an imidazolidine-2,4-dione.
Manufacturing Process
20 g of nitrofurantoin are placed in 100 cc of dimethylformamide and the solution is heated to 75°C to 80°C. This temperature is maintained and 100 cc of 40% formaldehyde are added, followed by 10 g of freshly distilled morpholine. The heating is continued for one hour, the mixture cooled and filtered and the precipitate obtained is washed with 95% alcohol. 20 g of the desired product are obtained as yellow crystals which melt at 206°C.
Therapeutic Function
Antibacterial
nifurfoline Preparation Products And Raw materials
Raw materials
Preparation Products
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nifurfoline Suppliers
- Tel
- 17691182729 18161915376
- 1046@dideu.com
- Country
- China
- ProdList
- 10008
- Advantage
- 58
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