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nifurfoline

Product Name
nifurfoline
CAS No.
3363-58-4
Chemical Name
nifurfoline
Synonyms
nifurfoline;3-[(Morpholino)methyl]-1-[(5-nitrofurfurylidene)amino]hydantoin;2,4-Imidazolidinedione, 3-(4-morpholinylmethyl)-1-[[(5-nitro-2-furanyl)methylene]amino]-;3-(morpholin-4-ylmethyl)-1-[(E)-(5-nitrofuran-2-yl)methylideneamino]imidazolidine-2,4-dione
CBNumber
CB8911340
Molecular Formula
C13H15N5O6
Formula Weight
337.29
MOL File
3363-58-4.mol
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nifurfoline Property

Melting point:
206°; also reported as mp 194-196°
Boiling point:
486.5±55.0 °C(Predicted)
Density 
1.63±0.1 g/cm3(Predicted)
pka
5.39±0.10(Predicted)
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Hazard and Precautionary Statements (GHS)

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nifurfoline Chemical Properties,Usage,Production

Originator

Furobactil,Carrion,France,1974

Definition

ChEBI: Nifurfoline is an imidazolidine-2,4-dione.

Manufacturing Process

20 g of nitrofurantoin are placed in 100 cc of dimethylformamide and the solution is heated to 75°C to 80°C. This temperature is maintained and 100 cc of 40% formaldehyde are added, followed by 10 g of freshly distilled morpholine. The heating is continued for one hour, the mixture cooled and filtered and the precipitate obtained is washed with 95% alcohol. 20 g of the desired product are obtained as yellow crystals which melt at 206°C.

Therapeutic Function

Antibacterial

nifurfoline Preparation Products And Raw materials

Raw materials

Preparation Products

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nifurfoline Suppliers

Shaanxi DIDU pharmaceutical and Chemical Co., Ltd
Tel
17691182729 18161915376
Email
1046@dideu.com
Country
China
ProdList
10007
Advantage
58

3363-58-4, nifurfolineRelated Search:


  • nifurfoline
  • 3-[(Morpholino)methyl]-1-[(5-nitrofurfurylidene)amino]hydantoin
  • 3-(morpholin-4-ylmethyl)-1-[(E)-(5-nitrofuran-2-yl)methylideneamino]imidazolidine-2,4-dione
  • 2,4-Imidazolidinedione, 3-(4-morpholinylmethyl)-1-[[(5-nitro-2-furanyl)methylene]amino]-
  • 3363-58-4