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thenalidine

Product Name
thenalidine
CAS No.
86-12-4
Chemical Name
thenalidine
Synonyms
Thenalidin;Sandostene;Thenaldine;thenalidine;Thenophenopiperidine;thenalidine USP/EP/BP;1-Methyl-4-[phenyl(2-thienylmethyl)amino]piperidine;4-Piperidinamine, 1-methyl-N-phenyl-N-(2-thienylmethyl)-
CBNumber
CB8914477
Molecular Formula
C17H22N2S
Formula Weight
286.43
MOL File
86-12-4.mol
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thenalidine Property

Melting point:
95-97°
Boiling point:
bp0.02 158-160°
Density 
1.140±0.06 g/cm3(Predicted)
pka
pKa 3.36±0.06(H2O t undefined I = 0.30 (NaCl)) (Uncertain);8.39±0.07(H2O t undefined I = 0.30 (NaCl)) (Uncertain)
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Usbiological
Product number
467467
Product name
Thenalidine
Packaging
10mg
Price
$460
Updated
2021/12/16
TRC
Product number
T343000
Product name
Thenalidine
Packaging
100mg
Price
$1320
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
API0012611
Product name
THENALIDINE
Purity
95.00%
Packaging
5MG
Price
$497.83
Updated
2021/12/16
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thenalidine Chemical Properties,Usage,Production

Uses

Thenalidine is an antihistamine that has anticholinergic properties which is used as an antipruritic drugs.

Definition

ChEBI: Thenalidine is a dialkylarylamine and a tertiary amino compound.

brand name

Sanbosten.

World Health Organization (WHO)

Thenalidine, a piperidine antihistamine, was introduced in 1953 for the management of dermatologic and allergic conditions. By 1958 its use had been associated with cases of severe neutropenia, two of them fatal, which led to its withdrawal in the United States of America and subsequently in the United Kingdom. Over the next fifteen years, continued reports of its association with cases of neutropenia resulted in further withdrawals in many countries. It is apparently still available, however, in some combination products.

Synthesis

Thenalidine is synthesized by alkylation of 1-methyl-4-phenylaminopiperidine with 2-chloromethyl thiophene .

thenalidine Preparation Products And Raw materials

Raw materials

Preparation Products

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thenalidine Suppliers

Dideu Industries Group Limited
Tel
+86-29-89586680 +86-15129568250
Email
1026@dideu.com
Country
China
ProdList
28965
Advantage
58
Hubei Jusheng Technology Co.,Ltd.
Tel
18871490254
Fax
027-59599243
Email
linda@hubeijusheng.com
Country
CHINA
ProdList
28180
Advantage
58
Shaanxi Didu New Materials Co. Ltd
Tel
+86-89586680 +86-13289823923
Email
1026@dideu.com
Country
China
ProdList
9069
Advantage
58
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View Lastest Price from thenalidine manufacturers

Dideu Industries Group Limited
Product
thenalidine 86-12-4
Price
US $1.10/g
Min. Order
1g
Purity
99.9%
Supply Ability
100 Tons Min
Release date
2021-06-16