4-acetylpiperidinium chloride

Product Name: 4-acetylpiperidinium chloride
CAS No.: 89895-06-7
Chemical Name: 4-acetylpiperidinium chloride
Synonyms: 4-Acetyl-piperidine HCl;4-acetylpiperidinium chloride;1-(4-Piperidinyl)ethanone HCl;1-(Piperidin-4-yl)ethanone, HCl;4-Acetylpiperidine hydrochloride;4-Acetylpiperidine hydrochloride,98%;1-(4-Piperidyl)ethanone Hydrochloride;1-(piperidin-4-yl)ethan-1-one HCL form;1-(4-Piperidinyl)ethanone hydrochloride;1-(Piperidin-4-yl)ethanone hydrochloride
CBNumber: CB8919902
Molecular Formula: C7H14ClNO
Formula Weight: 163.65
MOL File: 89895-06-7.mol

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4-acetylpiperidinium chloride Property

Melting point:: 151-158°C
storage temp.: under inert gas (nitrogen or Argon) at 2-8°C
solubility: DMSO (Slightly), Methanol (Slightly)
form: Solid
color: White to Off-White

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Safety

HS Code: 2933399990

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P321Specific treatment (see … on this label).

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P362Take off contaminated clothing and wash before reuse.

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N-Bromosuccinimide Price

TRC

Product number: P482030
Product name: 1-(4-Piperidinyl)ethanoneHydrochloride
Packaging: 5g
Price: $475
Updated: 2021/12/16

TRC

Product number: P482030
Product name: 1-(4-Piperidinyl)ethanoneHydrochloride
Packaging: 10g
Price: $875
Updated: 2021/12/16

AK Scientific

Product number: W9267
Product name: 1-(Piperidin-4-yl)ethanonehydrochloride
Packaging: 1g
Price: $155
Updated: 2021/12/16

Matrix Scientific

Product number: 076339
Product name: 1-(Piperidin-4-yl)ethanone hydrochloride
Purity: 95+%
Packaging: 250mg
Price: $278
Updated: 2021/12/16

AK Scientific

Product number: W9267
Product name: 1-(Piperidin-4-yl)ethanonehydrochloride
Packaging: 5g
Price: $424
Updated: 2021/12/16

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4-acetylpiperidinium chloride Chemical Properties,Usage,Production

Uses

1-(4-Piperidinyl)ethanone is used in the synthesis of oral antagonists for the treatment of rheumatoid arthritis. Also used in the synthesis of p38 mitogen activated protein kinase.

Synthesis

206989-61-9

89895-06-7

General procedure for the synthesis of 1-(4-piperidinyl)ethanone hydrochloride from 1-N-BOC-4-acetylpiperidine: To an anhydrous dichloromethane (5 mL) solution of 1-N-BOC-4-acetylpiperidine (350 mg, 1.54 mmol) was slowly added a dioxane solution (2 mL) of 4 M HCl at 0 °C. The reaction mixture was stirred continuously at 0°C for 2 hours. Upon completion of the reaction, the mixture was concentrated by rotary evaporator to afford 1-(4-piperidinyl)ethanone hydrochloride (260 mg, 100% yield) as a white solid, which could be used directly in the subsequent reaction without further purification.

References

[1] Patent: WO2013/96744, 2013, A1. Location in patent: Page/Page column 192
[2] Patent: EP3255042, 2017, A2. Location in patent: Paragraph 0209; 0213

4-acetylpiperidinium chloride Preparation Products And Raw materials

Raw materials

Preparation Products

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4-acetylpiperidinium chloride Suppliers

China 65 India 2 United States 3 Global 70

Nanjing Chemlin Chemical Co., Ltd

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89895-06-7, 4-acetylpiperidinium chlorideRelated Search:

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89895-06-7