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2-amino-6-methylpyridin-3-ol

Product Name
2-amino-6-methylpyridin-3-ol
CAS No.
20348-16-7
Chemical Name
2-amino-6-methylpyridin-3-ol
Synonyms
Einecs 243-752-7;2-Amino-3-Hydroxy-6-Picoline;2-amino-6-methylpyridin-3-ol;3-Pyridinol, 2-amino-6-methyl-;2-Amino-3-hydroxy-6-methylpyridine;2-amino-6-methylpyridin-3-ol ISO 9001:2015 REACH;N1,N4-bis(2-chloroethyl)cyclohexane-1,4-dicarboxamide
CBNumber
CB8931508
Molecular Formula
C6H8N2O
Formula Weight
124.14
MOL File
20348-16-7.mol
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2-amino-6-methylpyridin-3-ol Property

Melting point:
153-154.5 °C
Boiling point:
342.7±42.0 °C(Predicted)
Density 
1.245±0.06 g/cm3(Predicted)
storage temp. 
under inert gas (nitrogen or Argon) at 2–8 °C
pka
5.46±0.23(Predicted)
Appearance
Yellow to brown Solid
InChI
InChI=1S/C6H8N2O/c1-4-2-3-5(9)6(7)8-4/h2-3,9H,1H3,(H2,7,8)
InChIKey
WJRVHFJZHFWCMS-UHFFFAOYSA-N
SMILES
C1(N)=NC(C)=CC=C1O
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Safety

HazardClass 
IRRITANT
HS Code 
2933399990
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

TRC
Product number
A618070
Product name
2-amino-6-methylpyridin-3-ol
Packaging
100mg
Price
$65
Updated
2021/12/16
Matrix Scientific
Product number
064029
Product name
2-Amino-6-methylpyridin-3-ol
Packaging
500mg
Price
$52
Updated
2021/12/16
Biosynth Carbosynth
Product number
FA123519
Product name
2-Amino-6-methylpyridin-3-ol
Packaging
250mg
Price
$57.5
Updated
2021/12/16
Matrix Scientific
Product number
064029
Product name
2-Amino-6-methylpyridin-3-ol
Packaging
1g
Price
$80
Updated
2021/12/16
Biosynth Carbosynth
Product number
FA123519
Product name
2-Amino-6-methylpyridin-3-ol
Packaging
500mg
Price
$100
Updated
2021/12/16
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2-amino-6-methylpyridin-3-ol Chemical Properties,Usage,Production

Synthesis

15128-90-2

20348-16-7

General procedure for the synthesis of 2-amino-3-hydroxy-6-methylpyridine from 3-hydroxy-6-methyl-2-nitropyridine: 3-hydroxy-6-methyl-2-nitropyridine (30 g, 194.6 mmol) was dissolved in ethanol and the hydrogenation reaction was carried out for 1 hr at 50 °C using hydrogen (5 psi) and 20% Pd(OH)2/C catalyst. Upon completion of the reaction, the catalyst was removed by filtration and the filtrate was concentrated under reduced pressure to afford the target product 2-amino-3-hydroxy-6-methylpyridine as a brown solid (23.68 g, 98% yield). The NMR data of the product was consistent with the expected structure.

References

[1] Bioorganic and Medicinal Chemistry Letters, 2005, vol. 15, # 10, p. 2679 - 2684
[2] Patent: US2002/169200, 2002, A1
[3] Patent: US2004/92538, 2004, A1. Location in patent: Page 41-42
[4] Patent: WO2006/51410, 2006, A1. Location in patent: Page/Page column 40
[5] Patent: WO2008/51533, 2008, A2. Location in patent: Page/Page column 81-82

2-amino-6-methylpyridin-3-ol Preparation Products And Raw materials

Raw materials

Preparation Products

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2-amino-6-methylpyridin-3-ol Suppliers

Jinan Kewei Biotechnology Co., LTD
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15315592897
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China
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PharmaBlock Sciences (Nanjing),Inc.
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Capot Chemical Co., Ltd
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View Lastest Price from 2-amino-6-methylpyridin-3-ol manufacturers

Career Henan Chemica Co
Product
2-amino-6-methylpyridin-3-ol 20348-16-7
Price
US $9.20/ASSAYS
Min. Order
1KG
Purity
99%
Supply Ability
Customized
Release date
2020-10-27
Dideu Industries Group Limited
Product
2-amino-6-methylpyridin-3-ol 20348-16-7
Price
US $1.10/g
Min. Order
1g
Purity
99.00%
Supply Ability
100 Tons Min
Release date
2021-09-27