(9R)-6'-methoxycinchonan-9-ol
- Product Name
- (9R)-6'-methoxycinchonan-9-ol
- CAS No.
- 572-59-8
- Chemical Name
- (9R)-6'-methoxycinchonan-9-ol
- Synonyms
- (9R)-;Epiquindine;Epiquinidine;9-Epiquinidine;(9R)-6'-methoxycinchonan-9-ol;(8R,9R)-6'-Methoxycinchonan-9-ol;Cinchonan-9-ol, 6'-methoxy-, (9R)-;(R)-(6-methoxy-4-quinolyl)-[(2R,4S,5R)-5-vinylquinuclidin-2-yl]methanol;(R)-[(4S,5R,7R)-5-ethenyl-1-azabicyclo[2.2.2]octan-7-yl]-(6-methoxyquinolin-4-yl)methanol
- CBNumber
- CB8939382
- Molecular Formula
- C20H24N2O2
- Formula Weight
- 324.42
- MOL File
- 572-59-8.mol
(9R)-6'-methoxycinchonan-9-ol Property
- Melting point:
- 111-113°
- alpha
- D25 +107.8° (c = 1.02 in ethanol)
- Boiling point:
- 462.75°C (rough estimate)
- Density
- 1.1294 (rough estimate)
- refractive index
- 1.5700 (estimate)
- storage temp.
- 2-8°C
- form
- Solid-Liquid Mixture
- pka
- 12.80±0.20(Predicted)
- color
- White to off-white
Safety
- Hazard Codes
- Xn
- Risk Statements
- 22-42/43
- Safety Statements
- 22-36/37-45
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Danger
- Hazard statements
-
H302Harmful if swallowed
H317May cause an allergic skin reaction
H334May cause allergy or asthma symptoms or breathing difficulties if inhaled
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P342+P311IF experiencing respiratory symptoms: call a POISON CENTER or doctor/physician.
N-Bromosuccinimide Price
- Product number
- Q685005
- Product name
- 9-epi-Quinidine
- Packaging
- 100mg
- Price
- $155
- Updated
- 2021/12/16
- Product number
- PXT0002529
- Product name
- EPIQUINIDINE
- Purity
- 95.00%
- Packaging
- 5MG
- Price
- $500.05
- Updated
- 2021/12/16
(9R)-6'-methoxycinchonan-9-ol Chemical Properties,Usage,Production
Description
This alkaloid is stereoisomeric with epiQuinine and occurs in 'Quinoidine', the mixture of amorphous bases left after extraction of the four primary alkaloids of Cinchona bark. It crystallizes in colourless leaflets from Et20 and is fluorescent in dilute H2S04, It is dextrorotatory with [α]19D + 102.4° (c 0.8648, EtOH) and furnishes a dihydrochloride, m.p. 195-6°C (dec.); [α]20D + 45.5° (c 0.8012, EtOH); a hydrobromide, m.p. 240°C; thiocyanate, m.p. 193°C; [α]20D + 44.5° (H20) and the dibenzoyl-(+)-tartrate, m.p. 167°C; [α]201D + 3.7° (c 0.8068, EtOH-CHCI 3 ). Catalytic hydrogenation with Pd gives the dihydro derivative, m.p. 122°C; [α]22D + 73.1° (c 0.766, EtOH).
Uses
The 9-epimer of Quinidine (Q685000). Antimalarial.
References
Thron, Dirscherl., Annalen, 521,48 (1935)
(9R)-6'-methoxycinchonan-9-ol Preparation Products And Raw materials
Raw materials
Preparation Products
(9R)-6'-methoxycinchonan-9-ol Suppliers
- Tel
- --
- Fax
- --
- info@trc-canada.com
- Country
- Canada
- ProdList
- 6038
- Advantage
- 71