ChemicalBook > CAS DataBase List > 4-o-Tolyl-thiazol-2-ylamine

4-o-Tolyl-thiazol-2-ylamine

Product Name
4-o-Tolyl-thiazol-2-ylamine
CAS No.
5330-79-0
Chemical Name
4-o-Tolyl-thiazol-2-ylamine
Synonyms
2-AMino-4-o-tolylthiazol;2-AMino-4-o-tolylthiazole;4-(o-Tolyl)thiazol-2-aMine;2-Amino-4-(2-tollyl)thiazole;2-Amino-4-(2-Methylphenyl)Thiazole;2-Thiazolamine, 4-(2-methylphenyl)-;[4-(2-methylphenyl)thiazol-2-yl]amine;4-(2-methylphenyl)-1,3-thiazol-2-amine;4-methyl-1,3-[thiazol-14C1]benzothiazol-2-amine;[Phenyl-U-14C6]4-methyl-1,3-benzothiazol-2-amine
CBNumber
CB8947169
Molecular Formula
C10H10N2S
Formula Weight
190.26
MOL File
5330-79-0.mol
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4-o-Tolyl-thiazol-2-ylamine Property

Melting point:
81-82 °C
Boiling point:
349.7±11.0 °C(Predicted)
Density 
1.219±0.06 g/cm3(Predicted)
storage temp. 
under inert gas (nitrogen or Argon) at 2–8 °C
pka
4.34±0.10(Predicted)
Appearance
Light yellow to yellow Solid
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Safety

HS Code 
2934999090
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P337+P313IF eye irritation persists: Get medical advice/attention.

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N-Bromosuccinimide Price

TRC
Product number
T536855
Product name
4-(o-Tolyl)thiazol-2-amine
Packaging
500mg
Price
$155
Updated
2021/12/16
AK Scientific
Product number
5947AJ
Product name
4-(2-Methylphenyl)-1,3-thiazol-2-amine
Packaging
1g
Price
$112
Updated
2021/12/16
SynQuest Laboratories
Product number
7H70-1-50
Product name
4-(o-Tolyl)thiazol-2-amine
Packaging
1g
Price
$228
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
CHM0012217
Product name
4-O-TOLYL-THIAZOL-2-YLAMINE
Purity
95.00%
Packaging
1G
Price
$968.97
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
CHM0012217
Product name
4-O-TOLYL-THIAZOL-2-YLAMINE
Purity
95.00%
Packaging
2.5G
Price
$1445.42
Updated
2021/12/16
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4-o-Tolyl-thiazol-2-ylamine Chemical Properties,Usage,Production

Synthesis

17356-08-0

577-16-2

5330-79-0

GENERAL STEPS: At room temperature, o-methylacetophenone (0.5 mmol), thiourea (0.5 mmol) and triethylamine (0.5 mmol) were dissolved in acetonitrile (3 mL) in a round bottom flask. Subsequently, carbon tetrabromide (0.5 mmol) was added to the reaction system and the reaction was initiated with stirring. The reaction lasted from 2 to 6 hours, during which the progress of the reaction was monitored by thin layer chromatography (TLC). Upon completion of the reaction, water (5 mL) was added to the mixture and extracted with ethyl acetate (3 x 5 mL). The organic phases were combined, dried with anhydrous magnesium sulfate, filtered and concentrated under reduced pressure to obtain the crude product. Finally, the crude product was purified by silica gel column chromatography using a gradient mixture of hexane/ethyl acetate as eluent to obtain analytically pure 2-amino-4-o-tolylthiazole.

References

[1] Tetrahedron Letters, 2015, vol. 56, # 41, p. 5623 - 5627
[2] European Journal of Medicinal Chemistry, 2013, vol. 66, p. 305 - 313
[3] Journal of the American Chemical Society, 1950, vol. 72, p. 3722
[4] Bioorganic and Medicinal Chemistry Letters, 2014, vol. 24, # 23, p. 5428 - 5431
[5] Chemical Biology and Drug Design, 2017, vol. 90, # 5, p. 778 - 790

4-o-Tolyl-thiazol-2-ylamine Preparation Products And Raw materials

Raw materials

Preparation Products

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4-o-Tolyl-thiazol-2-ylamine Suppliers

China 49 Europe 2 Germany 1 India 1 Ukraine 1 United Kingdom 2 United States 7 Global 63
J & K SCIENTIFIC LTD.
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18210857532; 18210857532
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86-10-82849933
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jkinfo@jkchemical.com
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China
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Shanghai Topbiochem Technology Co., Ltd
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021-58170097
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info@topbiochem.com
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China
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Shanghai Topbiochem Technology Co., Ltd
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+86-21-60341587
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+86-21-61294319
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sales@topbiochem.com
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China
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Shanghai Yolne Chemical Co., Ltd.
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021-62960152
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021-52212593
Email
934678158@qq.com
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China
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Nanjing Credit Trading Co.,Ltd
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025-52164950
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025-86800069
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Googlexu_0114@sina.com
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China
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Bide Pharmatech Ltd.
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400-164-7117 13681763483
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+86-21-61629029
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product02@bidepharm.com
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Shanghai ShiXian Chemical Technology Co., Ltd.
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18681884732
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021-51632502
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2245256225@qq.com
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China
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ShangHai AmK Pharmaceutical Technology Co., Ltd.
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微信 17321281695 18019252918
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17321281695
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sale@amkchem.com
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China
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Accela ChemBio Inc.
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+1(858) 699-3322
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+1(858) 876-1948
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marketing@accelachem.com
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United States
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Shanghai Boyners Pharm-Tech Co., Ltd.
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13817873692
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021-31329586
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mkt@boynerspharm.com
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China
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1707
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View Lastest Price from 4-o-Tolyl-thiazol-2-ylamine manufacturers

Career Henan Chemical Co
Product
4-o-Tolyl-thiazol-2-ylamine 5330-79-0
Price
US $1.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
200kg
Release date
2020-01-09

5330-79-0, 4-o-Tolyl-thiazol-2-ylamine Related Search:

2-(2-ANILINO-1,3-THIAZOL-4-YL)BENZENECARBOXYLIC ACID 4-(2,4-DIMETHYL-PHENYL)-THIAZOL-2-YLAMINE ETHYL 2-(2-AMINO-1,3-THIAZOL-4-YL)BENZENECARBOXYLATE 7-METHOXY-4,5-DIHYDRONAPHTHO[1,2-D][1,3]THIAZOL-2-AMINE HYDROBROMIDE ETHYL 2-(2-([3-(TRIFLUOROMETHYL)BENZOYL]AMINO)-1,3-THIAZOL-4-YL)BENZENECARBOXYLATE ETHYL 2-(2-[(([(2-CHLORO-6-FLUOROBENZYL)OXY]IMINO)METHYL)AMINO]-1,3-THIAZOL-4-YL)BENZENECARBOXYLATE (4-(2,4-DIMETHYLPHENYL)(2,5-THIAZOLYL))PHENYLAMINE ETHYL 2-(2-ANILINO-1,3-THIAZOL-4-YL)BENZENECARBOXYLATE ETHYL 2-(2-[(2-FURYLCARBONYL)AMINO]-1,3-THIAZOL-4-YL)BENZENECARBOXYLATE ETHYL 2-(2-[(([(4-NITROBENZYL)OXY]IMINO)METHYL)AMINO]-1,3-THIAZOL-4-YL)BENZENECARBOXYLATE ETHYL 2-(2-[(2-THIENYLCARBONYL)AMINO]-1,3-THIAZOL-4-YL)BENZENECARBOXYLATE ETHYL 2-(2-([(4-CHLOROPHENYL)SULFONYL]AMINO)-1,3-THIAZOL-4-YL)BENZENECARBOXYLATE ETHYL 2-[2-(([3-(TRIFLUOROMETHYL)ANILINO]CARBONYL)AMINO)-1,3-THIAZOL-4-YL]BENZENECARBOXYLATE ETHYL 2-[2-(3,4-DICHLOROANILINO)-1,3-THIAZOL-4-YL]BENZENECARBOXYLATE ETHYL 2-[2-(([3-(2-CHLORO-6-FLUOROPHENYL)-5-METHYL-4-ISOXAZOLYL]CARBONYL)AMINO)-1,3-THIAZOL-4-YL]BENZENECARBOXYLATE ETHYL 2-(2-([(3-CHLOROANILINO)CARBONYL]ANILINO)-1,3-THIAZOL-4-YL)BENZENECARBOXYLATE ETHYL 2-(2-[(4-METHOXYBENZOYL)AMINO]-1,3-THIAZOL-4-YL)BENZENECARBOXYLATE ETHYL 2-(2-[(([(3-CHLOROBENZYL)OXY]IMINO)METHYL)AMINO]-1,3-THIAZOL-4-YL)BENZENECARBOXYLATE

  • 4-(2-methylphenyl)-1,3-thiazol-2-amine
  • [4-(2-methylphenyl)thiazol-2-yl]amine
  • 2-AMino-4-o-tolylthiazole
  • 2-AMino-4-o-tolylthiazol
  • (E)-3-[3-[(E)-2-carboxyethenyl]phenyl]-2-propenoic acid
  • 2-Amino-4-(2-tollyl)thiazole
  • 4-(o-Tolyl)thiazol-2-aMine
  • [Phenyl-U-14C6]4-methyl-1,3-benzothiazol-2-amine
  • 4-methyl-1,3-[thiazol-14C1]benzothiazol-2-amine
  • 2-Thiazolamine, 4-(2-methylphenyl)-
  • 2-Amino-4-(2-Methylphenyl)Thiazole
  • 5330-79-0