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Protirelin acetate

Product Name
Protirelin acetate
CAS No.
120876-23-5
Chemical Name
Protirelin acetate
Synonyms
TRH Acetate;TRF Acetate;TSH-RF Acetate;Protirelin acetate;Protirelin Acetate,TRF Acetate,TRH Acetate,TSH-RF Acetate, >99%
CBNumber
CB8947811
Molecular Formula
C38H56N12O14
Formula Weight
904.92324
MOL File
120876-23-5.mol
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Protirelin acetate Property

storage temp. 
Store at -20°C
form 
Solid
color 
White to off-white
Water Solubility 
Water : 50 mg/mL (110.51 mM)
Sequence
{pGlu}-His-Pro-NH2
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Crysdot
Product number
CD31004277
Product name
ProtirelinAcetate
Purity
98+%
Packaging
50mg
Price
$76
Updated
2021/12/16
Crysdot
Product number
CD31004277
Product name
ProtirelinAcetate
Purity
98+%
Packaging
100mg
Price
$125
Updated
2021/12/16
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Protirelin acetate Chemical Properties,Usage,Production

Uses

Protirelin Acetate is a highly conserved neuropeptide that exerts the hormonal control of thyroid-stimulating hormone (TSH) levels as well as neuromodulatory functions.

in vivo

Protirelin (TRH) is an evolutionarily ancient neuropeptide, having its origin before the divergence of protostomes and deuterostomes, and may ancestrally have been involved in the control of postembryonic growth and reproduction[1]. The effect of the thyrotropin-releasing hormone (Protirelin, TRH), one of the hypothalamic releasing hormones, on body temperature is investigated in the rat. Protirelin, in doses of 1, 5, 10 and 20 mg/kg, is injected intraperitoneally to male Wistar rats weighing 200-250 g. Protirelin causes a temporary rise in body temperature dose-dependently. The thyroidectomized rats injected 20 mg/kg of Protirelin which induces a significant hyperthermia in the sham-operated animals, fail to show a rise in body temperature. The present results suggest that a release of thyroid hormone might participate in the hyperthermic action of Protirelin[2].

References

[1] Van Sinay E, et al. Evolutionarily conserved TRH neuropeptide pathway regulates growth in Caenorhabditis elegans. Proc Natl Acad Sci U S A. 2017 May 16;114(20):E4065-E4074. DOI:10.1073/pnas.1617392114
[2] Noda Y, et al. Hyperthermia induced by thyrotropin-releasing hormone (TRH, Protirelin) in the rat. Kurume Med J. 1979;26(2):107-12. DOI:10.2739/kurumemedj.26.107

Protirelin acetate Preparation Products And Raw materials

Raw materials

Preparation Products

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Protirelin acetate Suppliers

MedChemexpress LLC
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021-58955995
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609-228-5909
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sales@medchemexpress.cn
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United States
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4861
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58
ShangHai Caerulum Pharma Discovery Co., Ltd.
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18149758185
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sales-cpd@caerulumpharma.com
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China
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3506
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58
Creative Peptides
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info@creative-peptides.com
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United States
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6083
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Shanghai YuanYe Biotechnology Co., Ltd.
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021-61312847; 18021002903
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QQ:3008007432
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3008007409@qq.com
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China
ProdList
71826
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60
ShangHai Biochempartner Co.,Ltd
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177-54423994 17754423994
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QQ:2853530913
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2853530910@QQ.com
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China
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8000
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Beijing Solarbio Science & Tecnology Co., Ltd.
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010-50973130 18101056239
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3193328036@qq.com
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China
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29760
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Musechem
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+1-800-259-7612
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info@musechem.com
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United States
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4660
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Hangzhou Peptidego Biotech Co.,Ltd.
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0571-87213919
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Eric@peptidego.com
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China
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7408
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Career Henan Chemica Co
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+86-0371-86658258 +8613203830695
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0371-86658258
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laboratory@coreychem.com
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China
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30229
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BOC Sciences
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+1-631-485-4226
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1-631-614-7828
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inquiry@bocsci.com
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United States
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19552
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View Lastest Price from Protirelin acetate manufacturers

Dingwang Technology (Wuhan) Co., Ltd.
Product
Protirelin Acetate 120876-23-5
Price
US $0.00/gram
Min. Order
1gram
Purity
99%
Supply Ability
20 tons
Release date
2022-11-04

120876-23-5, Protirelin acetateRelated Search:


  • Protirelin acetate
  • Protirelin Acetate,TRF Acetate,TRH Acetate,TSH-RF Acetate, >99%
  • TRF Acetate
  • TRH Acetate
  • TSH-RF Acetate
  • 120876-23-5
  • 24305-35-4