ChemicalBook > CAS DataBase List > 4-Methoxy-1H-quinolin-2-one

4-Methoxy-1H-quinolin-2-one

Product Name
4-Methoxy-1H-quinolin-2-one
CAS No.
27667-34-1
Chemical Name
4-Methoxy-1H-quinolin-2-one
Synonyms
4-Methoxy-quinolin-2-ol;4-Methoxy-1H-quinolin-2-one;2(1H)-Quinolinone, 4-methoxy-
CBNumber
CB8958437
Molecular Formula
C10H9NO2
Formula Weight
175.18
MOL File
27667-34-1.mol
More
Less

4-Methoxy-1H-quinolin-2-one Property

Melting point:
271 °C
Boiling point:
124 °C(Press: 8 Torr)
Density 
1.24±0.1 g/cm3(Predicted)
storage temp. 
2-8°C
form 
solid
pka
10.86±0.70(Predicted)
Appearance
White to yellow Solid
More
Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P337+P313IF eye irritation persists: Get medical advice/attention.

More
Less

N-Bromosuccinimide Price

Sigma-Aldrich
Product number
PH018693
Product name
4-Methoxy-2(1H)-quinolinone
Purity
AldrichCPR
Packaging
1g
Price
$201
Updated
2023/06/20
AK Scientific
Product number
2647AB
Product name
4-Methoxyquinolin-2(1H)-one
Packaging
250mg
Price
$108
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
CHM0237528
Product name
4-METHOXYQUINOLIN-2(1H)-ONE
Purity
95.00%
Packaging
5MG
Price
$498.65
Updated
2021/12/16
Chemenu
Product number
CM143044
Product name
4-methoxyquinolin-2(1H)-one
Purity
95%
Packaging
5g
Price
$701
Updated
2021/12/16
Crysdot
Product number
CD11154768
Product name
4-Methoxyquinolin-2(1H)-one
Purity
95+%
Packaging
5g
Price
$743
Updated
2021/12/16
More
Less

4-Methoxy-1H-quinolin-2-one Chemical Properties,Usage,Production

Synthesis

70254-44-3

27667-34-1

General procedure for the synthesis of 4-methoxy-2-quinolinone from 2-hydroxyquinolin-4(1H)-one: to a suspension of 2,4-dihydroxyquinoline (3.00 g, 18.6 mmol) and potassium carbonate (5.14 g, 37.2 mmol) in acetone (500 mL) was added dropwise dimethyl sulfate (2.1 mL). The reaction mixture was heated to reflux for 5 hours. Upon completion of the reaction, the solvent was removed by vacuum distillation and the residue was ground with an appropriate amount of water. The crude product was collected by filtration, washed with water and subsequently purified by grinding with methanol to afford 4-methoxy-2-quinolinone (1.76 g, 54% yield) as a white solid. The 1H NMR data of the product were in agreement with literature reports (Reisch et al., Arch. Pharm., 1980, 313, 751-755).

References

[1] Patent: US2003/207868, 2003, A1
[2] Patent: US2002/99208, 2002, A1

4-Methoxy-1H-quinolin-2-one Preparation Products And Raw materials

Raw materials

Preparation Products

More
Less

4-Methoxy-1H-quinolin-2-one Suppliers

A.J Chemicals
Tel
--
Fax
--
Email
sales@ajchem.in
Country
India
ProdList
6100
Advantage
58