PYRROLIDINYL DIAMINOPYRIMIDINE OXIDE
- Product Name
- PYRROLIDINYL DIAMINOPYRIMIDINE OXIDE
- CAS No.
- 55921-65-8
- Chemical Name
- PYRROLIDINYL DIAMINOPYRIMIDINE OXIDE
- Synonyms
- 2,6-diamino-4-(pyrrolidin-1-yl)pyrimidine 1-oxide;Kopyrrol;Pyrrolidinyl Diaminopyrimide oxide;PYRROLIDINYL DIAMINOPYRIMIDINE OXIDE;2,4-Diamino-6-pyrrolidinopyrimidine 3-oxide;3-oxy-6-pyrrolidin-1-yl-pyrimidine-2,4-diamine;6-(1-Pyrrolidinyl)-2,4-pyrimidinediamine 3-oxide;6-(pyrrolidin-1-yl)pyrimidine-2,4-diamine 3-oxide;2,4-PyriMidinediaMine,6-(1-pyrrolidinyl)-, 3-oxide;TIANFU-CHEM - PYRROLIDINYL DIAMINOPYRIMIDINE OXIDE
- CBNumber
- CB8964098
- Molecular Formula
- C8H13N5O
- Formula Weight
- 195.22
- MOL File
- 55921-65-8.mol
PYRROLIDINYL DIAMINOPYRIMIDINE OXIDE Property
- Melting point:
- 278℃ (DEC.)
- Boiling point:
- 549.3±60.0 °C(Predicted)
- Density
- 1.60
- storage temp.
- 2-8°C(protect from light)
- pka
- 4.89±0.10(Predicted)
- InChI
- InChI=1S/C8H13N5O/c9-6-5-7(11-8(10)13(6)14)12-3-1-2-4-12/h5H,1-4,9H2,(H2,10,11)
- InChIKey
- FMVJDYVWXJHAFZ-UHFFFAOYSA-N
- SMILES
- C1(N)=NC(N2CCCC2)=CC(N)=[N+]1[O-]
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Danger
- Hazard statements
-
H314Causes severe skin burns and eye damage
- Precautionary statements
-
P280Wear protective gloves/protective clothing/eye protection/face protection.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P310Immediately call a POISON CENTER or doctor/physician.
N-Bromosuccinimide Price
- Product number
- 153401
- Product name
- 2,6-Diamino-4-(pyrrolidin-1-yl)pyrimidine 1-oxide
- Purity
- 95%
- Packaging
- 5g
- Price
- $583
- Updated
- 2021/12/16
- Product number
- 153401
- Product name
- 2,6-Diamino-4-(pyrrolidin-1-yl)pyrimidine 1-oxide
- Purity
- 95%
- Packaging
- 10g
- Price
- $972
- Updated
- 2021/12/16
- Product number
- CM167546
- Product name
- 2,6-Diamino-4-(pyrrolidin-1-yl)pyrimidine1-oxide
- Purity
- 97%
- Packaging
- 5g
- Price
- $316
- Updated
- 2021/12/16
- Product number
- CD11104344
- Product name
- 2,6-Diamino-4-(pyrrolidin-1-yl)pyrimidine1-oxide
- Purity
- 97%
- Packaging
- 5g
- Price
- $338
- Updated
- 2021/12/16
PYRROLIDINYL DIAMINOPYRIMIDINE OXIDE Chemical Properties,Usage,Production
Uses
Pyrrolidinyl Diaminopyrimidine Oxide is a hair growth stimulant that can be used to treat hair loss. It can also be used in cosmetics to invent a dermocosmetic composition having a whitening or dark circle removal or anti-glare effect by containing a pyrrolidinyl diaminopyrimidine oxide compound as an active ingredient.
Synthesis
Pyrrolidinyl Diaminopyrimidine Oxide is prepared by the reaction of pyrrolidine and 2,6-diamino-4-chloro-pyrimidine N-oxide. The steps are as follows:
Pyrrolidine (7.47 g, 0.105 mol) and 2,6-diamino-4-chloropyrimidine N-oxide (16 g, 0.1 mol) were added to 100 mL ethanol solution, 10% NaOH (0.11 mol) was added dropwise under stirring, and then the reaction was carried out at 80 °C for 120 min. The progress of the reaction was monitored by high performance liquid chromatography. After the reaction is completed, it is cooled to below 5°C, the solvent is removed by filtration, the obtained solid product is washed with water, and recrystallized with hot water to obtain 2,6-diamino-4-pyrrolidinopyrimidine N-oxide as a colorless crystalline solid. Yield 92% (17.96 g), white crystalline powder, mp 276-278°C. IR spectrum (neat), νmax, cm-1: 1195 (C-N), 1346 (C-C), 1463 (N-O), 1613 (C=N), 1651 (C=C), 2856 (C-H), 3265 (C-H), 3298 (O-H), 3428 (N-H). 1H NMR spectrum (500 MHz, DMSO), δ, ppm: 1.87 s (4H, CH2), 3.25 s (4H, N-CH2), 5.08 s (1H, Ar-H), 6.78 s (4H, NH2). 13C NMR spectrum (101 MHz, DMSO), δC, ppm: 26.81, 48.05, 74.81, 153.85, 154.47, 154.60.
PYRROLIDINYL DIAMINOPYRIMIDINE OXIDE Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from PYRROLIDINYL DIAMINOPYRIMIDINE OXIDE manufacturers
- Product
- Pyrrolidinyl Diaminopyrimidine Oxide 55921-65-8
- Price
- US $0.00/Kg/Bag
- Min. Order
- 1KG
- Purity
- 99%min HPLC
- Supply Ability
- 500KG
- Release date
- 2021-07-17
- Product
- PYRROLIDINYL DIAMINOPYRIMIDINE OXIDE 55921-65-8
- Price
- US $6.00/kg
- Min. Order
- 1kg
- Purity
- 99%
- Supply Ability
- 2000KG/Month
- Release date
- 2024-08-02
- Product
- Pyrrolidinyl Diaminopyrimidine Oxide 55921-65-8
- Price
- US $35.00/kg
- Min. Order
- 1kg
- Purity
- 99%
- Supply Ability
- 5000kg/Week
- Release date
- 2024-05-07