3-Iodopyridine-2-carboxylic acid
- Product Name
- 3-Iodopyridine-2-carboxylic acid
- CAS No.
- 73841-32-4
- Chemical Name
- 3-Iodopyridine-2-carboxylic acid
- Synonyms
- 3-Iodopicolinicaci;3-Iodopicolinic acid;3-Iodopyridine-2-carboxylic acid;2-Pyridinecarboxylic acid, 3-iodo-;3-Iodopyridine-2-carboxylic acid ISO 9001：2015 REACH
- CBNumber
- CB8967433
- Molecular Formula
- C6H4INO2
- Formula Weight
- 249.01
- MOL File
- 73841-32-4.mol
3-Iodopyridine-2-carboxylic acid Property
- storage temp.
- under inert gas (nitrogen or Argon) at 2–8 °C
- Appearance
- White to yellow Solid
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Danger
- Hazard statements
-
H340May cause genetic defects
H351Suspected of causing cancer
H360May damage fertility or the unborn child
- Precautionary statements
-
P201Obtain special instructions before use.
P202Do not handle until all safety precautions have been read and understood.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P308+P313IF exposed or concerned: Get medical advice/attention.
P405Store locked up.
P501Dispose of contents/container to..…
N-Bromosuccinimide Price
- Product number
- I718815
- Product name
- 3-IodopicolinicAcid
- Packaging
- 50mg
- Price
- $100
- Updated
- 2021/12/16
- Product number
- W8180
- Product name
- 3-Iodopicolinicacid
- Packaging
- 250mg
- Price
- $114
- Updated
- 2021/12/16
- Product number
- 076246
- Product name
- 3-Iodopicolinic acid
- Purity
- 95+%
- Packaging
- 250mg
- Price
- $297
- Updated
- 2021/12/16
- Product number
- W8180
- Product name
- 3-Iodopicolinicacid
- Packaging
- 5g
- Price
- $467
- Updated
- 2021/12/16
- Product number
- 076246
- Product name
- 3-Iodopicolinic acid
- Purity
- 95+%
- Packaging
- 1g
- Price
- $639
- Updated
- 2021/12/16
3-Iodopyridine-2-carboxylic acid Chemical Properties,Usage,Production
Synthesis
98-98-6
73841-32-4
General procedure for the synthesis of 3-iodopyridine-2-carboxylic acid from 2-pyridinecarboxylic acid: 2,2,6,6-tetramethylpiperidine (8.48 g, 60 mmol) was dissolved in tetrahydrofuran (100 mL), cooled to -78 °C, and N-butyllithium (2.5 mol/L, 16 mL, 40 mmol) was added slowly dropwise. After the dropwise addition, it was slowly warmed up to room temperature and kept for 30 minutes. Cooled again to -78 °C, the solution was added dropwise to a tetrahydrofuran suspension of pyridine-2-carboxylic acid (2.46 g, 20 mmol). After completion of the dropwise addition, the reaction mixture was allowed to react at room temperature for 30 minutes. Subsequently cooled to -30°C, a tetrahydrofuran solution of iodine (15.23 g, 60 mmol) was added dropwise to the reaction flask. The mixture was stirred at room temperature for 1 h. Water was added and left overnight to precipitate the solid. Filtration gave 3-iodopyridine-2-carboxylic acid (3.3 g, 66% yield).
References
[1] Patent: CN106317027, 2017, A. Location in patent: Paragraph 0246; 0247; 0248
[2] Patent: US2008/312209, 2008, A1. Location in patent: Page/Page column 13
[3] Patent: WO2007/7018, 2007, A1. Location in patent: Page/Page column 38-39
[4] Tetrahedron, 2002, vol. 58, # 33, p. 6723 - 6728
[5] Patent: WO2006/25783, 2006, A1. Location in patent: Page/Page column 120-121
3-Iodopyridine-2-carboxylic acid Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from 3-Iodopyridine-2-carboxylic acid manufacturers
- Product
- 3-Iodopyridine-2-carboxylic acid 73841-32-4
- Price
- US $1.10/g
- Min. Order
- 1g
- Purity
- 99.00%
- Supply Ability
- 100 Tons min
- Release date
- 2021-09-01
- Product
- 3-Iodopyridine-2-carboxylic acid 73841-32-4
- Price
- US $15.00-10.00/KG
- Min. Order
- 1KG
- Purity
- 99%+ HPLC
- Supply Ability
- Monthly supply of 1 ton
- Release date
- 2021-07-11
- Product
- 3-Iodopyridine-2-carboxylic acid 73841-32-4
- Price
- US $15.00-10.00/KG
- Min. Order
- 1KG
- Purity
- 99%+ HPLC
- Supply Ability
- Monthly supply of 1 ton
- Release date
- 2021-07-09