4-(4-FLUOROPHENYL)-1H-IMIDAZOLE
Uses- Product Name
- 4-(4-FLUOROPHENYL)-1H-IMIDAZOLE
- CAS No.
- 65020-70-4
- Chemical Name
- 4-(4-FLUOROPHENYL)-1H-IMIDAZOLE
- Synonyms
- 4-(4-Fluorophenyl)imidazole;5-(4-Fluorophenyl)-3H-imidazole;4-(4-FLUOROPHENYL)-1H-IMIDAZOLE;4-(4-Fluorophenyl)iMidazole, 97%;4-(4-Fluorophenyl)imidazole, 97%,;1H-Imidazole, 5-(4-fluorophenyl)-;4-(4-Fluorophenyl)-1H-imidazole;JR-9093, 4-(4-Fluorophenyl)-1H-imidazole, 97%
- CBNumber
- CB8972587
- Molecular Formula
- C9H7FN2
- Formula Weight
- 162.16
- MOL File
- 65020-70-4.mol
4-(4-FLUOROPHENYL)-1H-IMIDAZOLE Property
- Melting point:
- 124-129 °C
- form
- solid
- InChI
- 1S/C9H7FN2/c10-8-3-1-7(2-4-8)9-5-11-6-12-9/h1-6H,(H,11,12)
- InChIKey
- QYDAFWKRBZYBOB-UHFFFAOYSA-N
- SMILES
- Fc1ccc(cc1)-c2c[nH]cn2
N-Bromosuccinimide Price
- Product number
- 687065
- Product name
- 4-(4-Fluorophenyl)-1H-imidazole
- Purity
- 97%
- Packaging
- 5g
- Price
- $97.6
- Updated
- 2025/07/31
- Product number
- F621558
- Product name
- 4-(4-Fluorophenyl)-1h-imidazole
- Packaging
- 500mg
- Price
- $65
- Updated
- 2021/12/16
- Product number
- F621558
- Product name
- 4-(4-Fluorophenyl)-1h-imidazole
- Packaging
- 100mg
- Price
- $45
- Updated
- 2021/12/16
- Product number
- PC904946
- Product name
- 4-(4-Fluorophenyl)-1H-imidazole
- Purity
- 98%
- Packaging
- 10g
- Price
- $130
- Updated
- 2021/12/16
- Product number
- 3H31-3-8M
- Product name
- 4-(4-Fluorophenyl)-1H-imidazole
- Purity
- 98%
- Packaging
- 10g
- Price
- $208
- Updated
- 2021/12/16
4-(4-FLUOROPHENYL)-1H-IMIDAZOLE Chemical Properties,Usage,Production
Uses
4-(4-Fluorophenyl)-1H-imidazolium is an imidazolium heterocyclic derivative that can be used as an intermediate in pharmaceutical and chemical synthesis.
Synthesis
A mixture of 2-bromo-1-(4-fluorophenyl)ethanone (10.9 g, 50 mmol) and formamide (14 mL, 350 mmol) was stirred at 170 ??C and under nitrogen for 4 hours. The reaction mixture was cooled and mixed with ethyl acetate (40 mL). Saturated aqueous sodium bicarbonate (50 mL) was carefully added while the mixture was cooled in an ice water bath. The aqueous layer was separated and extracted with ethyl acetate (2 x 40mL). The combined organic solutions were washed with water (30 mL) and brine (30 mL), dried (Na2SO 4) and concentrated. Rapid chromatography on silica gel (10-100% hexane solution of ethyl acetate) yielded 4-(4-fluorophenyl)-1H-imidazole (3.46 g, 21 mmol, 43% yield) as a solid.
4-(4-FLUOROPHENYL)-1H-IMIDAZOLE Preparation Products And Raw materials
Raw materials
Preparation Products
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