4-THUJANOL Property

Melting point:

58-62 °C

Boiling point:

201.7±8.0 °C(Predicted)

Density 

1.030±0.06 g/cm3(Predicted)

FEMA 

3239 | 4-THUJANOL

storage temp. 

-20°C

solubility 

Chloroform, Ethanol (Slightly), Hexanes (Slightly)

pka

15.22±0.40(Predicted)

color 

Off-White

Odor

at 1.00 % in dipropylene glycol. minty eucalyptus green terpene

Odor Type

herbal

optical activity

[α]20/D +31.5±2°, c = 1% in ethanol

JECFA Number

441

LogP

2.53

EPA Substance Registry System

Bicyclo[3.1.0]hexan-2-ol, 2-methyl-5-(1-methylethyl)- (546-79-2)

Safety

WGK Germany 

3

F 

8-10-23

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H226Flammable liquid and vapour

4-THUJANOL Chemical Properties,Usage,Production

Chemical Properties

Thujan-4-ol has an odor reminiscent of terpineol.

Occurrence

Reported found in peppermint oil (trans-form), lemon juice, mandarin peel oil, mandarin, nutmeg, peppermint, rosemary, scotch spearmint, tarragon, thyme, black currant (buds), Vitis vinifera L., ginger, spearmint oil, other Mentha oils, pepper, sweet marjoram, cardamom, origanum, dill herb, Oscimum basilicum varieties and laurel.

Uses

Sabinene Hydrate is a monoterpene and an essential oil component, found to have antifungal activity.

Uses

cis-4-Thujanol is a related compound of (+)-Sabinene (S080750), a component of juniper berry oil having antibacterial and antifungal activity.

Definition

ChEBI: Sabinene hydrate is a p-menthane monoterpenoid.

Aroma threshold values

Aroma characteristics at 1.0%: earthy camphoreous pine and turpentine-like with citrus grapefruit nuances.

Taste threshold values

Taste characteristics at 5 ppm: woody, citrus orange and grapefruit-like.

Synthesis

The Grignard reaction with sabina ketone yields two isomers, of which one is identical to an alcohol isolated from American peppermint oil; synthetic routes for the preparation of both the cis- and trans-form are also available.