4-HYDRAZINO-BENZOIC ACID ETHYL ESTER HCL
- Product Name
- 4-HYDRAZINO-BENZOIC ACID ETHYL ESTER HCL
- CAS No.
- 40566-85-6
- Chemical Name
- 4-HYDRAZINO-BENZOIC ACID ETHYL ESTER HCL
- Synonyms
- ethyl 4-hydrazineylbenzoate;ETHYL-4-HYDRAZINYL BENZOATE HCl;Ethyl 4-hydrazinylbenzoate hydrochloride;Ethyl 4-hydrazinobenzoate hydrochloride (1:1);4-ethoxycarbonylphenylhydrazine hydrochloride;4-Hydrazino-benzoic acid ethyl ester hydrochloride;Benzoic acid, 4-hydrazino-, ethyl ester, Monohydrochloride
- CBNumber
- CB91010647
- Molecular Formula
- C9H13ClN2O2
- Formula Weight
- 216.67
- MOL File
- 40566-85-6.mol
4-HYDRAZINO-BENZOIC ACID ETHYL ESTER HCL Property
- storage temp.
- Inert atmosphere,Room Temperature
- Appearance
- Off-white to yellow Solid
N-Bromosuccinimide Price
- Product number
- E940630
- Product name
- Ethyl4-HydrazinylbenzoateHydrochloride
- Packaging
- 50mg
- Price
- $45
- Updated
- 2021/12/16
- Product number
- E940630
- Product name
- Ethyl4-HydrazinylbenzoateHydrochloride
- Packaging
- 100mg
- Price
- $90
- Updated
- 2021/12/16
- Product number
- P000641957
- Product name
- Ethyl 4-hydrazinylbenzoate hydrochloride
- Purity
- 97%
- Packaging
- 250mg
- Price
- $36
- Updated
- 2021/12/16
- Product number
- P000641957
- Product name
- Ethyl 4-hydrazinylbenzoate hydrochloride
- Purity
- 97%
- Packaging
- 1g
- Price
- $89
- Updated
- 2021/12/16
- Product number
- 2824AJ
- Product name
- 4-Hydrazino-benzoicacidethylesterhydrochloride
- Packaging
- 1g
- Price
- $176
- Updated
- 2021/12/16
4-HYDRAZINO-BENZOIC ACID ETHYL ESTER HCL Chemical Properties,Usage,Production
Synthesis
94-09-7
40566-85-6
Step 1: Synthesis of ethyl 4-hydrazinobenzoate hydrochloride. A concentrated hydrochloric acid solution of ethyl 4-aminobenzoate (2 g, 12.181 mmol) was stirred and cooled at -20 °C. To this solution was slowly added aqueous sodium nitrite (925 mg, 13.40 mmol) in 22 mL of concentrated hydrochloric acid. The above mixture was slowly added dropwise to a pre-cooled (-10°C) solution of tin chloride (13.8 g, 60.905 mmol) in hydrochloric acid (15 mL). Stirring of the reaction mixture was continued at the same temperature for 30 minutes. Upon completion of the reaction, the precipitate was collected by filtration and washed with ether (2 x 20 mL) to afford 2.2 g of the target product ethyl 4-hydrazinylbenzoate hydrochloride as an off-white solid. The product was characterized by 1H NMR (300 MHz, DMSO-d6): δ1.29 (t, J=7.2 Hz, 3H), 4.26 (q, J=7.5 Hz, 2H), 6.99 (d, J=7.8 Hz, 2H), 7.87 (d, J=8.4 Hz, 2H), 8.95 (br s, 1H), 10.48 (br s, 2H) ; APCI-MS (m/z) 181 (M+H)+.
References
[1] Journal of Medicinal Chemistry, 1993, vol. 36, # 11, p. 1529 - 1538
[2] Patent: WO2015/87234, 2015, A1. Location in patent: Page/Page column 39
4-HYDRAZINO-BENZOIC ACID ETHYL ESTER HCL Preparation Products And Raw materials
Raw materials
Preparation Products
4-HYDRAZINO-BENZOIC ACID ETHYL ESTER HCL Suppliers
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